ID   ARAB_GEOSE              Reviewed;         564 AA.
AC   Q9S468;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Ribulokinase {ECO:0000255|HAMAP-Rule:MF_00520};
DE            EC=2.7.1.16 {ECO:0000255|HAMAP-Rule:MF_00520};
GN   Name=araB {ECO:0000255|HAMAP-Rule:MF_00520};
OS   Geobacillus stearothermophilus (Bacillus stearothermophilus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=1422;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=T-6;
RA   Gilead-Gropper S., Shoham Y.;
RT   "The L-arabinose utilization gene cluster from Bacillus stearothermophilus
RT   T-6.";
RL   Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribulose = ADP + D-ribulose 5-phosphate + H(+);
CC         Xref=Rhea:RHEA:17601, ChEBI:CHEBI:15378, ChEBI:CHEBI:17173,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58121, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC         Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC       ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC       step 2/3. {ECO:0000255|HAMAP-Rule:MF_00520}.
CC   -!- SIMILARITY: Belongs to the ribulokinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00520}.
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DR   EMBL; AF160811; AAD45717.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9S468; -.
DR   SMR; Q9S468; -.
DR   UniPathway; UPA00145; UER00566.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019150; F:D-ribulokinase activity; IEA:RHEA.
DR   GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniRule.
DR   CDD; cd07781; FGGY_RBK; 1.
DR   HAMAP; MF_00520; Ribulokinase; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005929; Ribulokinase.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR01234; L-ribulokinase; 1.
PE   3: Inferred from homology;
KW   Arabinose catabolism; ATP-binding; Carbohydrate metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN           1..564
FT                   /note="Ribulokinase"
FT                   /id="PRO_0000198356"
SQ   SEQUENCE   564 AA;  62202 MW;  DBFFDBFFC56EDDB5 CRC64;
     MGKKYVIGID YGTESGRAVL VDLEGNEIAD HVTPYPHGVI DEVLPESNVQ LEPDWALQHP
     ADYIEVLATA VPTVLQKSGV NPADVIGVGI DFTSCTMLPV DASGEPLCLK PEFRNRPHSW
     VKLWKHHAAQ DEANLLNEIA AKRGEAFLPR YGGKISSEWM IAKIWQILNE DPEIYEQTDL
     FLEGTDWVIF KMTGNIVRNS CAAGYKSIWH KQDGYPSKEF FRALDPRLEH LTETKLRGPI
     VPLGTRAGVL TNEMAAMMGL LPGTAVAVGN VDAHAAVPGV GVVEPGKLVM AMGTSICHML
     LGTEEKYVEG MCGVVEDGII PGYFGYEAGQ SAVGDIFAWY VEQGVPAYVK EAAEKEGISV
     HEWLEKRAAA YRPGETGLLA LDWWNGNRSV LVDTDLTGLI VGYTLLTKPE EIYRALLEAT
     AFGTRKIIDA FVENGVKVDE LYACGGLPQK DKLLMQIYAD VTNREIKIAA SKQTPAVGAA
     MFAAVAAGKE NGGYESIVEA ARNMGKVREE TFKPIPENVA MYEQLYQEYT KLHDYFGRGE
     NDVMKRLKHW KETTRAAKEF MSLW