KI26L_DROPS
ID KI26L_DROPS Reviewed; 1171 AA.
AC Q29MB2;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 3.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Kinesin-like protein GA13060;
GN ORFNames=GA13060;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIF26 subfamily. {ECO:0000255|PROSITE-
CC ProRule:PRU00283}.
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DR EMBL; CH379060; EAL33782.2; -; Genomic_DNA.
DR RefSeq; XP_001356717.2; XM_001356681.3.
DR AlphaFoldDB; Q29MB2; -.
DR SMR; Q29MB2; -.
DR STRING; 7237.FBpp0280610; -.
DR EnsemblMetazoa; FBtr0282172; FBpp0280610; FBgn0073098.
DR GeneID; 4817387; -.
DR KEGG; dpo:Dpse_GA13060; -.
DR eggNOG; KOG4280; Eukaryota.
DR HOGENOM; CLU_008498_0_0_1; -.
DR InParanoid; Q29MB2; -.
DR OMA; KQSDVCA; -.
DR Proteomes; UP000001819; Chromosome 4.
DR Bgee; FBgn0073098; Expressed in insect adult head and 1 other tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; PTHR24115; 2.
DR Pfam; PF00225; Kinesin; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Cytoskeleton; Microtubule; Motor protein;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1..1171
FT /note="Kinesin-like protein GA13060"
FT /id="PRO_0000307304"
FT DOMAIN 40..400
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1124..1143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1043..1063
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1097
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1127..1141
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1171 AA; 124349 MW; E55E675AA8D724A1 CRC64;
MASSISRNGG FCGALQRAPP PMPPGLARRL SSRECYGVGK VKVMLRVSDR APDKDSPLDP
EFMALDKKKR QVTLTDPRNV CPPPQAAQER GPMVAAPKMF AFDNLFTAED KQSDVCASAL
SEVIPAVLEG SDGCLLAMGY PSTGQPHTVL GGDVATGAGA GAATGTGTGT GSVAACSLGA
APCAIAWLYK GIQERRQKSG ARFSVRVSAV GVSATKPDAL STDLLISHAA ESDDSPGIYL
RDDFLGGPTE LRAPTAERAA LFLDSALAGR LKSSGSTSTP AGGGPAPLES ALIFTLHVYQ
YSLSRKGGVA GGRSRLHIID LGGCANRSGG LPLSGIGNIL LAILSGQRHP PHKDHPLTPL
LKDCLAPITC HVAIVAHVLH EQSYQDALST IQIASRIHRL RRRKHRVPMP LAVGLAQGLS
GGGGSSAGSG ADPSSSEISA DTVIYMGPND DATDGEHPPV YLPSLSAGDN RAIMSKALKG
SGLEKPPTQM KAGLSSPMMM KKAMAAAGEK VKKLPGNSPM GSLKRQAAAG ACSSPLVPHE
QQQQQQQIAH GSPIPIPRHM VSKGSNVPSP KGSPLRRAHA GAHPGAALEQ LEAGMRKITE
EQWIDGPRVS RAKVAEARHL MREVNHVKQC ETWVDGPKSL SCRSLTAGNL PAAGAQTQGY
GFMDSHKKTM IRQWVETQTS QVFQSPATVS ASNSPTALHW KLSQLKQKSL DLPERPAFPP
EQQSMDLPQQ CFESQPLLGQ DMSLPPDGDE DQDSGPSEVP PALPLFDDPL GSRDISHDSL
HRMLSRHVSR EQLHEADLVA SRASSSHHQH QHHRPSSQRS IDCGLQVTEE EIARTMAREQ
EHSMHPLSAL SHCDNLSFVS SFNMACESFS ECGERARHQF DQLARLHEIF TSQLAMAEVT
PSAALFRTDV SSVFSEPVFR FNVGQSSVCS EPAYRLTPSP PKQPSHSPSQ GSLPSLNGIM
EIAGMDDYAL LRQPDGASDP SLPKSEKRFA PQHDDICELD EKAMAAAVGK RNSLEDAQHK
LNEITNILPL AAQSRLPLLP LNTSSEAYDS GHDSNSTPRT SKHSGISRRA ESGYHSVATV
RDSDESSFAS GMSKGQRHRI TISGGGGGGC GAGGGGSATG NYQRHSHGVG GHKKHRHRHE
GNGGGNKGLC NWLLTPFSCT YPETEGEISD F
