ID   KIF3C_BOVIN             Reviewed;         792 AA.
AC   A0JN40;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Kinesin-like protein KIF3C;
GN   Name=KIF3C;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Microtubule-based anterograde translocator for membranous
CC       organelles. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of KIF3A and KIF3C. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. Kinesin II subfamily.
CC       {ECO:0000255|PROSITE-ProRule:PRU00283}.
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DR   EMBL; BC126505; AAI26506.1; -; mRNA.
DR   RefSeq; NP_001071623.1; NM_001078155.1.
DR   AlphaFoldDB; A0JN40; -.
DR   SMR; A0JN40; -.
DR   STRING; 9913.ENSBTAP00000025475; -.
DR   PaxDb; A0JN40; -.
DR   PRIDE; A0JN40; -.
DR   Ensembl; ENSBTAT00000025475; ENSBTAP00000025475; ENSBTAG00000019138.
DR   GeneID; 777770; -.
DR   KEGG; bta:777770; -.
DR   CTD; 3797; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019138; -.
DR   VGNC; VGNC:30604; KIF3C.
DR   eggNOG; KOG4280; Eukaryota.
DR   GeneTree; ENSGT00940000153739; -.
DR   HOGENOM; CLU_001485_22_4_1; -.
DR   InParanoid; A0JN40; -.
DR   OrthoDB; 862274at2759; -.
DR   TreeFam; TF105223; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000019138; Expressed in prefrontal cortex and 104 other tissues.
DR   ExpressionAtlas; A0JN40; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072686; C:mitotic spindle; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005876; C:spindle microtubule; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IBA:GO_Central.
DR   GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR   GO; GO:0051231; P:spindle elongation; IBA:GO_Central.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24115; PTHR24115; 1.
DR   Pfam; PF00225; Kinesin; 2.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Coiled coil; Cytoplasm; Cytoskeleton; Microtubule;
KW   Motor protein; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..792
FT                   /note="Kinesin-like protein KIF3C"
FT                   /id="PRO_0000284074"
FT   DOMAIN          10..363
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          249..287
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          628..792
FT                   /note="Globular"
FT                   /evidence="ECO:0000255"
FT   REGION          749..792
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          374..627
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        253..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         97..104
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   792 AA;  89487 MW;  786FE3FEB3F36098 CRC64;
     MASKTKASEA LKVVARCRPL SRKEEAAGHE QILTMDVKLG QVTLRNPRAA LGELPKTFTF
     DAVYDASSKQ ADLYDETVRP LVDSVLQGFN GTVFAYGQTG TGKTYTMQGT WVEPEQRGVI
     PNAFEHIFTH ISRSQNQQYL VRASYLEIYQ EEIRDLVSKE PGKRLELKEN PETGVYIKDL
     SSFVTKNVKE IEHVMNLGNQ TRAVGSTHMN EVSSRSHAIF VITVECSERG SDGQDHIRVG
     KLNLVDLAGS ERQNKAGPNT TGGTATQPTG GGGGGGGGGG GGERPKEASK INLSLSALGN
     VIAALSGNRS THIPYRDSKL TRLLQDSLGG NAKTIMVATL GPASHSYDES LSTLRFANRA
     KNIKNKPRVN EDPKDTLLRE FQEEIARLKA QLEKKGMLGK RLRRKSSRRK KAVSAPAGYP
     EGPVIEAWVA EEEDDNNNNH RPPQPILETA LDKNMENYLQ EQKERLEEEK AAIQDDRSLV
     SEEKKKLLEE KEKMLEDLRR EQEATELLAA KYKAMESKLL IGGRNIMDHT NEQQKMLELK
     RQEIAEQKRR EREMQQEMML RDEETMELRG TYTSLQQEVE VKTKKLKKLY AKLQAVKAEI
     QDQHDEYIRV RQDLEEAQNE QTRELKLKYL IIENFIPPEE KNKIMNRLFL DCEEEQWKFQ
     PLVPSGANSS QMKKRPTSAV GYKRPISQYA RVAMAMGSHP RYRAENIMFL ELDVSPPAVF
     EMEFSHDQDQ DPRALHMERL MRLDSFLERP STSKVRKSRS WCQSPQRPPP PTAHASLAAS
     AALRPTTVLD HE