ID   KIFA3_STRPU             Reviewed;         828 AA.
AC   Q26626;
DT   10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Kinesin-associated protein 3;
DE   AltName: Full=SpKAP115;
GN   Name=KAP115;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 801-811 AND 815-828, AND
RP   SUBUNIT.
RC   TISSUE=Egg;
RX   PubMed=8636215; DOI=10.1083/jcb.132.3.371;
RA   Wedaman K.P., Meyer D.W., Rashid D.J., Cole D.G., Scholey J.M.;
RT   "Sequence and submolecular localization of the 115-kD accessory subunit of
RT   the heterotrimeric kinesin-II (KRP85/95) complex.";
RL   J. Cell Biol. 132:371-380(1996).
CC   -!- FUNCTION: Binds to the tail domain of the KRP85/KRP95 heterodimer to
CC       form a heterotrimeric kinesin-II complex and may regulate the spindle
CC       vesicle targeting of this complex.
CC   -!- SUBUNIT: Heterotrimer of a 115 kDa subunit (KAP115) and two kinesin-
CC       like subunits of 95 kDa (KRP95) and 85 kDa (KRP85).
CC       {ECO:0000269|PubMed:8636215}.
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DR   EMBL; U38655; AAC46997.1; -; mRNA.
DR   RefSeq; NP_999823.1; NM_214658.1.
DR   AlphaFoldDB; Q26626; -.
DR   SMR; Q26626; -.
DR   STRING; 7668.SPU_010954-tr; -.
DR   EnsemblMetazoa; NM_214658; NP_999823; GeneID_373539.
DR   EnsemblMetazoa; XM_030997530; XP_030853390; LOC105436387.
DR   GeneID; 373539; -.
DR   KEGG; spu:373539; -.
DR   CTD; 373539; -.
DR   eggNOG; KOG1222; Eukaryota.
DR   InParanoid; Q26626; -.
DR   OrthoDB; 535512at2759; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0035869; C:ciliary transition zone; IBA:GO_Central.
DR   GO; GO:0016939; C:kinesin II complex; IDA:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IEA:InterPro.
DR   GO; GO:0044782; P:cilium organization; IBA:GO_Central.
DR   GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR   GO; GO:0007017; P:microtubule-based process; IC:UniProtKB.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR008658; KAP3.
DR   PANTHER; PTHR15605; PTHR15605; 1.
DR   SMART; SM00185; ARM; 3.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Repeat.
FT   CHAIN           1..828
FT                   /note="Kinesin-associated protein 3"
FT                   /id="PRO_0000084304"
FT   REPEAT          332..372
FT                   /note="ARM 1"
FT   REPEAT          373..411
FT                   /note="ARM 2"
FT   REPEAT          577..611
FT                   /note="ARM 3"
SQ   SEQUENCE   828 AA;  94743 MW;  245DB749A41C6AFA CRC64;
     MQAEDARYLK RKVKGGSIDV HPTEKALVVN YELEATILGE MGDPMLGERK ECQKIIRLRS
     LNSTTDIAAL AREVVEKCKL IHPSKLPEVE QLLYYLQNRK ETTQKAGAKK GELTGKLKDP
     PPYEGTELNE VANINDIEDY IELLYEDNPE KVRGTALILQ LARNPDNLEE LQSNETVLGA
     LARVLREEWK HSVELATNIV YIFFCFSSFS QFHSIVAHFK IGALVMGVVE HELKKHLSWN
     EELLKKKKTA EENPASKRDF EKSTKKYHGL LKKQEQLLRV SFYLLLNLSE DPKVELKMKN
     KNIIRLLIKT LERDNAELLI LVVSFLKKLG IYVENKNEMA EQQIIERLAK LVPCDHEDLL
     NITLRLLLNL SFDTDLRGKM IKLGMLPKFV ELLANDNHRL VVLCVLYHVS QDDKAKSMFT
     YTDCIPMIMK MMLESPTERL EIELVALGIN LACNKHNAQL ICEGNGLRLL MRRALKFRDP
     LLLKMIRNIS QHDGPSKAQF IEYISDVARI IKESNDEELV VEALGIMANL TIPDLDYEMI
     INEFGLVPWI KEKLEPGAAE DDLVLEVVML VGTVATDDSC AAMLAKSGII QSLIELLNAK
     QEDDEIVCQI VYVFYQMVFH EATREVIIKL TQAPAYLIDL MHDKNSEIRK VCDNTLDIIS
     EFDEEWARKI KLEKFRWHNS QWLEMVESQQ IDDGEGGLMY GDESYSPYIQ ESDILDRPDL
     FYGQTGYEDG EMYDGQVTPE YVDEYGNVQN GEYLGRPASA MYGNRYQSEY ESLRPGSRVA
     YLTEDGQPLD EYGNPIEVYA ESVDQYGRPV TPTYQYGSQA QQGPGYPY