ID   KIL_BPMU                Reviewed;          74 AA.
AC   P03046; Q9T1Y0;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 3.
DT   12-AUG-2020, entry version 65.
DE   RecName: Full=Protein kil;
DE   AltName: Full=Gene product 5;
DE            Short=gp5;
DE   AltName: Full=Protein cim;
GN   Name=kil; Synonyms=cim; OrderedLocusNames=Mup05;
OS   Escherichia phage Mu (Bacteriophage Mu).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Muvirus.
OX   NCBI_TaxID=10677;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Priess H., Brauer B., Schmidt C., Kamp D.;
RT   "Sequence of the left end of Mu.";
RL   (In) Symonds N., Toussaint A., van de Putte P., Howe M.M. (eds.);
RL   Phage Mu, pp.277-296, Cold Spring Harbor Laboratory Press, New York (1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11922669; DOI=10.1006/jmbi.2002.5437;
RA   Morgan G.J., Hatfull G.F., Casjens S., Hendrix R.W.;
RT   "Bacteriophage Mu genome sequence: analysis and comparison with Mu-like
RT   prophages in Haemophilus, Neisseria and Deinococcus.";
RL   J. Mol. Biol. 317:337-359(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-47.
RX   PubMed=6269958; DOI=10.1016/0378-1119(81)90111-6;
RA   Engler J.A., van Bree M.P.;
RT   "The nucleotide sequence and protein-coding capability of the transposable
RT   element IS5.";
RL   Gene 14:155-163(1981).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=2531953; DOI=10.1016/0042-6822(89)90550-3;
RA   Waggoner B.T., Sultana K., Symonds N., Karlok M.A., Pato M.L.;
RT   "Identification of the bacteriophage Mu kil gene.";
RL   Virology 173:378-389(1989).
RN   [5]
RP   FUNCTION.
RX   PubMed=6234699; DOI=10.1016/0042-6822(84)90257-5;
RA   Waggoner B.T., Marrs C.F., Howe M.M., Pato M.L.;
RT   "Multiple factors and processes involved in host cell killing by
RT   bacteriophage Mu: characterization and mapping.";
RL   Virology 136:168-185(1984).
RN   [6]
RP   FUNCTION.
RX   PubMed=6237246; DOI=10.1007/bf00334111;
RA   Goosen N., van de Putte P.;
RT   "Hek: an Escherichia coli function involved in functional expression of the
RT   kil gene of bacteriophage Mu.";
RL   Mol. Gen. Genet. 196:170-172(1984).
RN   [7]
RP   INDUCTION.
RX   PubMed=2524470; DOI=10.1128/jb.171.6.3440-3448.1989;
RA   Stoddard S.F., Howe M.M.;
RT   "Localization and regulation of bacteriophage Mu promoters.";
RL   J. Bacteriol. 171:3440-3448(1989).
CC   -!- FUNCTION: Expression of the kil gene induces dramatic morphological
CC       changes in the host cell, which becomes enlarged and predominantly
CC       spherical and possibly dies. These changes might involved a direct or
CC       indirect interaction with host actin-like protein MreB.
CC       {ECO:0000269|PubMed:6234699, ECO:0000269|PubMed:6237246}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       Expression of early genes is repressed by viral Repc (latency) and
CC       favored by viral Ner protein. {ECO:0000269|PubMed:2524470}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA32387.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; M64097; AAA32387.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AF083977; AAF01084.1; -; Genomic_DNA.
DR   PIR; A03582; IUBPU.
DR   RefSeq; NP_050609.1; NC_000929.1.
DR   GeneID; 2636299; -.
DR   KEGG; vg:2636299; -.
DR   Proteomes; UP000002611; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Early protein; Host cytoplasm; Reference proteome.
FT   CHAIN           1..74
FT                   /note="Protein kil"
FT                   /id="PRO_0000077563"
SQ   SEQUENCE   74 AA;  8417 MW;  039C50DD897F3A70 CRC64;
     MARNIKMATD AQNWLQARGS HVNESYLGVA RPILEITYPP VELVKNAVRI MEHKSGVARS
     VWTARLNGCQ IIWR