KINB3_ARATH
ID KINB3_ARATH Reviewed; 114 AA.
AC Q9ZUU8;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=SNF1-related protein kinase regulatory subunit beta-3;
DE Short=AKIN subunit beta-3;
DE Short=AKINB3;
DE Short=AKINbeta3;
GN Name=KINB3; OrderedLocusNames=At2g28060; ORFNames=F24D13.15, T1E2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INTERACTION WITH KIN10;
RP KIN11 AND SNF4.
RX PubMed=15803412; DOI=10.1007/s11103-004-5111-1;
RA Gissot L., Polge C., Bouly J.P., Lemaitre T., Kreis M., Thomas M.;
RT "AKINbeta3, a plant specific SnRK1 protein, is lacking domains present in
RT yeast and mammals non-catalytic beta-subunits.";
RL Plant Mol. Biol. 56:747-759(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP INTERACTION WITH SNF4, COMPONENT OF A HETEROTRIMERIC COMPLEX, AND SUBUNIT.
RX PubMed=17028154; DOI=10.1104/pp.106.087718;
RA Gissot L., Polge C., Jossier M., Girin T., Bouly J.-P., Kreis M.,
RA Thomas M.;
RT "AKINbetagamma contributes to SnRK1 heterotrimeric complexes and interacts
RT with two proteins implicated in plant pathogen resistance through its
RT KIS/GBD sequence.";
RL Plant Physiol. 142:931-944(2006).
RN [8]
RP REVIEW.
RX PubMed=17166759; DOI=10.1016/j.tplants.2006.11.005;
RA Polge C., Thomas M.;
RT "SNF1/AMPK/SnRK1 kinases, global regulators at the heart of energy
RT control?";
RL Trends Plant Sci. 12:20-28(2007).
RN [9]
RP COMPONENT OF A HETEROTRIMERIC COMPLEX, AND SUBUNIT.
RX PubMed=25736509; DOI=10.1111/tpj.12813;
RA Emanuelle S., Hossain M.I., Moller I.E., Pedersen H.L., van de Meene A.M.,
RA Doblin M.S., Koay A., Oakhill J.S., Scott J.W., Willats W.G., Kemp B.E.,
RA Bacic A., Gooley P.R., Stapleton D.I.;
RT "SnRK1 from Arabidopsis thaliana is an atypical AMPK.";
RL Plant J. 82:183-192(2015).
RN [10]
RP REVIEW.
RX PubMed=27812990; DOI=10.1007/978-3-319-43589-3_17;
RA Margalha L., Valerio C., Baena-Gonzalez E.;
RT "Plant SnRK1 kinases: structure, regulation, and function.";
RL EXS 107:403-438(2016).
RN [11]
RP INTERACTION WITH FLZ PROTEINS.
RX PubMed=29945970; DOI=10.1074/jbc.ra118.002073;
RA Jamsheer K M., Shukla B.N., Jindal S., Gopan N., Mannully C.T., Laxmi A.;
RT "The FCS-like zinc finger scaffold of the kinase SnRK1 is formed by the
RT coordinated actions of the FLZ domain and intrinsically disordered
RT regions.";
RL J. Biol. Chem. 293:13134-13150(2018).
CC -!- FUNCTION: Regulatory subunit of the probable trimeric SNF1-related
CC protein kinase (SnRK) complex, which may play a role in a signal
CC transduction cascade regulating gene expression and carbohydrate
CC metabolism in higher plants.
CC -!- SUBUNIT: Subunit of a probable heterotrimeric complex consisting of an
CC alpha catalytic (KIN10 or KIN11) subunit, and a beta (KINB) and a gamma
CC (KING or SNF4) non-catalytic regulatory subunits (PubMed:17028154,
CC PubMed:25736509). Interacts with KIN10, KIN11 and SNF4. Interacts with
CC FLZ1, FLZ2, FLZ3, FLZ4, FLZ5, FLZ7, FLZ8, FLZ10, FLZ13, FLZ14, FLZ15
CC and FLZ16 (PubMed:29945970). {ECO:0000269|PubMed:15803412,
CC ECO:0000269|PubMed:17028154, ECO:0000269|PubMed:25736509,
CC ECO:0000269|PubMed:29945970}.
CC -!- TISSUE SPECIFICITY: Expressed in rosette (at the protein level).
CC Expressed in the whole plant and at the different developmental stage
CC with a higher level in stems. {ECO:0000269|PubMed:15803412}.
CC -!- DOMAIN: Kinase-interacting sequence (KIS) is specific for the alpha
CC catalytic subunit interaction and Association with SNF1 Complex (ASC)
CC is specific for the gamma non-catalytic regulatory subunit interaction.
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase beta subunit
CC family. {ECO:0000305}.
CC -!- CAUTION: Presents a truncated kinase-interacting sequence (KIS).
CC {ECO:0000305}.
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DR EMBL; AC005851; AAC98460.1; -; Genomic_DNA.
DR EMBL; AC006929; AAM15325.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08074.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61369.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61370.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61371.1; -; Genomic_DNA.
DR EMBL; AF491295; AAN03809.1; -; mRNA.
DR EMBL; BT009702; AAP88336.1; -; mRNA.
DR EMBL; AK228157; BAF00113.1; -; mRNA.
DR EMBL; AY085681; AAM62900.1; -; mRNA.
DR PIR; C84680; C84680.
DR RefSeq; NP_001323590.1; NM_001336142.1.
DR RefSeq; NP_001323591.1; NM_001336141.1.
DR RefSeq; NP_001323592.1; NM_001336140.1.
DR RefSeq; NP_565664.1; NM_128365.4.
DR AlphaFoldDB; Q9ZUU8; -.
DR SMR; Q9ZUU8; -.
DR BioGRID; 2700; 30.
DR IntAct; Q9ZUU8; 1.
DR STRING; 3702.AT2G28060.1; -.
DR PaxDb; Q9ZUU8; -.
DR PRIDE; Q9ZUU8; -.
DR ProteomicsDB; 238199; -.
DR EnsemblPlants; AT2G28060.1; AT2G28060.1; AT2G28060.
DR EnsemblPlants; AT2G28060.2; AT2G28060.2; AT2G28060.
DR EnsemblPlants; AT2G28060.3; AT2G28060.3; AT2G28060.
DR EnsemblPlants; AT2G28060.4; AT2G28060.4; AT2G28060.
DR GeneID; 817350; -.
DR Gramene; AT2G28060.1; AT2G28060.1; AT2G28060.
DR Gramene; AT2G28060.2; AT2G28060.2; AT2G28060.
DR Gramene; AT2G28060.3; AT2G28060.3; AT2G28060.
DR Gramene; AT2G28060.4; AT2G28060.4; AT2G28060.
DR KEGG; ath:AT2G28060; -.
DR Araport; AT2G28060; -.
DR TAIR; locus:2046208; AT2G28060.
DR eggNOG; KOG1616; Eukaryota.
DR HOGENOM; CLU_070949_3_1_1; -.
DR InParanoid; Q9ZUU8; -.
DR OMA; HHTLLNH; -.
DR OrthoDB; 956412at2759; -.
DR PhylomeDB; Q9ZUU8; -.
DR PRO; PR:Q9ZUU8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUU8; baseline and differential.
DR Genevisible; Q9ZUU8; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009569; C:chloroplast starch grain; IDA:TAIR.
DR GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR GO; GO:0031588; C:nucleotide-activated protein kinase complex; IDA:TAIR.
DR GO; GO:1901982; F:maltose binding; IDA:TAIR.
DR GO; GO:0019887; F:protein kinase regulator activity; IDA:TAIR.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0043562; P:cellular response to nitrogen levels; IEA:InterPro.
DR GO; GO:0009744; P:response to sucrose; IEA:InterPro.
DR InterPro; IPR006828; ASC_dom.
DR InterPro; IPR037256; ASC_dom_sf.
DR InterPro; IPR043554; KINB.
DR InterPro; IPR030067; KINB3.
DR PANTHER; PTHR46316; PTHR46316; 1.
DR PANTHER; PTHR46316:SF5; PTHR46316:SF5; 1.
DR Pfam; PF04739; AMPKBI; 1.
DR SMART; SM01010; AMPKBI; 1.
DR SUPFAM; SSF160219; SSF160219; 1.
PE 1: Evidence at protein level;
KW Carbohydrate metabolism; Reference proteome.
FT CHAIN 1..114
FT /note="SNF1-related protein kinase regulatory subunit beta-
FT 3"
FT /id="PRO_0000412192"
FT REGION 26..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..114
FT /note="Association with SNF1 complex (ASC)"
FT /evidence="ECO:0000250"
SQ SEQUENCE 114 AA; 12705 MW; 16A1737BCB764343 CRC64;
MNSQNPDDHE DTTVVGFEVP VSPVSSYNNV YSSTEDETRD PPAVPPHLQH SLLGNQGSME
LAYAPQNVVL NHLYIENRDA PRSVVALGFS HRFRTKFVTV VIYKPVQRRG SANV
