KIP_ARATH
ID KIP_ARATH Reviewed; 2587 AA.
AC Q6IMT0; Q9LTA4; Q9LTA5;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Protein KINKY POLLEN {ECO:0000303|PubMed:14675453};
DE Flags: Precursor;
GN Name=KIP {ECO:0000303|PubMed:14675453};
GN OrderedLocusNames=At5g49680 {ECO:0000312|Araport:AT5G49680};
GN ORFNames=K2I5.3 {ECO:0000312|EMBL:BAA98155.1},
GN K2I5.4 {ECO:0000312|EMBL:BAA98156.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:DAA00366.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE
RP SPECIFICITY.
RX PubMed=14675453; DOI=10.1046/j.1365-313x.2003.01933.x;
RA Procissi A., Guyon A., Pierson E.S., Giritch A., Knuiman B., Grandjean O.,
RA Tonelli C., Derksen J., Pelletier G., Bonhomme S.;
RT "KINKY POLLEN encodes a SABRE-like protein required for tip growth in
RT Arabidopsis and conserved among eukaryotes.";
RL Plant J. 36:894-904(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May be involved in membrane trafficking (By similarity).
CC Required for tip growth in pollen tubes and root hairs.
CC {ECO:0000250|UniProtKB:K7VLR4, ECO:0000269|PubMed:14675453}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:14675453}. Golgi
CC apparatus {ECO:0000250|UniProtKB:K7VLR4}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in pollen and roots, especially in
CC tip-growing cells, but also present in seedlings, stems, leaves, buds,
CC flowers, siliques and seeds. {ECO:0000269|PubMed:14675453}.
CC -!- DISRUPTION PHENOTYPE: Kinky-shaped pollen tubes due to periodic growth
CC arrests alternated with phases of tube axis reorientation of pollen
CC tube tip, as well as shorter and thicker root hairs. Lack of callose
CC plugs in pollen tubes. Reduced seed set. {ECO:0000269|PubMed:14675453}.
CC -!- SIMILARITY: Belongs to the SABRE family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA98155.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAA98156.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; BK000518; DAA00366.1; -; mRNA.
DR EMBL; AB025613; BAA98155.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AB025613; BAA98156.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95844.1; -; Genomic_DNA.
DR RefSeq; NP_001078738.1; NM_001085269.2.
DR AlphaFoldDB; Q6IMT0; -.
DR SMR; Q6IMT0; -.
DR STRING; 3702.AT5G49680.2; -.
DR iPTMnet; Q6IMT0; -.
DR PaxDb; Q6IMT0; -.
DR PRIDE; Q6IMT0; -.
DR ProteomicsDB; 237089; -.
DR EnsemblPlants; AT5G49680.2; AT5G49680.2; AT5G49680.
DR GeneID; 835031; -.
DR Gramene; AT5G49680.2; AT5G49680.2; AT5G49680.
DR KEGG; ath:AT5G49680; -.
DR Araport; AT5G49680; -.
DR TAIR; locus:2157052; AT5G49680.
DR eggNOG; KOG1910; Eukaryota.
DR HOGENOM; CLU_000876_0_0_1; -.
DR InParanoid; Q6IMT0; -.
DR OMA; CYVDGYV; -.
DR OrthoDB; 9668at2759; -.
DR PhylomeDB; Q6IMT0; -.
DR PRO; PR:Q6IMT0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6IMT0; baseline and differential.
DR Genevisible; Q6IMT0; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0090404; C:pollen tube tip; IDA:UniProtKB.
DR GO; GO:0035619; C:root hair tip; IDA:UniProtKB.
DR GO; GO:0009860; P:pollen tube growth; IMP:UniProtKB.
DR GO; GO:0048768; P:root hair cell tip growth; IMP:UniProtKB.
DR InterPro; IPR045167; FMP27.
DR InterPro; IPR019443; FMP27_C.
DR InterPro; IPR019441; FMP27_GFWDK_dom.
DR PANTHER; PTHR15678; PTHR15678; 1.
DR Pfam; PF10351; Apt1; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Developmental protein; Glycoprotein; Golgi apparatus;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..2587
FT /note="Protein KINKY POLLEN"
FT /evidence="ECO:0000255"
FT /id="PRO_0000432481"
FT REGION 103..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..814
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1571..1608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1646..1673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1729..1797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2274..2299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2319..2360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2442..2469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2533..2587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 691..716
FT /evidence="ECO:0000255"
FT COILED 2006..2036
FT /evidence="ECO:0000255"
FT COMPBIAS 105..119
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1575..1600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1646..1667
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1742..1787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2274..2292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2325..2360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2442..2459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2542..2562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2570..2587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 262
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 281
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 485
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1155
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1250
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1281
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1486
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1595
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1861
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1951
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 1981
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2036
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2278
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2513
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 2544
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 2587 AA; 290411 MW; D362301642A4B4FB CRC64;
MAAFLVMFIF TIALFVALLW VFFKSLPWIL RHSAGITLSF QFDGWNCLKD VALQFKKGSI
ESIVIGEFKA NLSQSLVELC ATAFIQDPKV IFSICDLKIV TRPSHSSKGP RKPKTRKSSS
GGKGKLMLFA NIGRFFSVSM TNMVVQTPKA TAEIKELELD LSKDRGSGNF FMKLYLLPIF
VQIGEPHVTS THSPEMDSDI CLARQTPSKT AEGSSSSSFH CEKISLSCEF GPNRKSSPSI
KNVEVDLANA VLNLNEKLLL KNKSSTSAAS KGEVIDSSSG NTTSEKPPKQ PMNVLVAKHA
SKFPEKVLFD LTKLEIRFVH QEHDFSIANS IKGFQLRSAK SQSGEDGKED TCLDFAMELQ
EMHLFRESEV SVLEMTKFGV FTKVYCPIQE SLPVRAEVEI KLGGIMSNII MTRFEPLLRL
HFSRKKKMVL KEERPTIAKS ETTGFKAVVW KCATSAPDVT VVLYNPGGSP IYQCGLDSFQ
ATANNMSNRG TVVQMELNEL TLCMVDEHKG CLKESLFGLE SDPGSLINIR KVRSEWGKKE
VLPEGDGSKG KQTLVVDVSE IGLLFSFRSV EALTVNAISS QAYIKSLTGS SSKNKQEKGA
HRSKPPSGRG TQLLKLNVER FSLNFAGDSS LENTVIDDPK RVNYGSQGGR IIISVSADGS
PRTASVFSTL SEEHEKLKYI ISFEILKFGF TLNKEIQSTQ VELETAKAIY QEFLEEPHQV
SRVTLCDIQN AKFVRRIGGG KEVSICSLFS ASNIAVRWEP DVHISMVELG LRLKSLVLTQ
KLKQHGNRNP EEASTVTGDK QKEEPTTTPN SLDKKKKKES IFAVDVEMLS ITAEAGDGVE
AEVQIQSIFS ENVGIGVLLE GFMLGFCGCR IVKSSRVQIS RIPSMPSTSS SVTPATGGTP
WDWIVQGVDI HICMPFRLQL RAIDDAVEEM LRALKLVTNA KTKLIFPIKK ESSTPKKPGS
KKVGRIRFGI RKLIFDIEEE PLQGWLDEHY HLMRKEAYEL AIRSKFLDEL MSSGNQVPKT
GGDESDGEKK ISFEGEEIDP QDPAIIQMMN EKLYKQSFSS YYKSCQSLRL SDGSGACKEG
FQAGFKMSTS RTSLLSVSVT DLDLSLTAIG GGEAGMIEIV KKLDPVAEEK DIPFSRLYGS
NLRLNTGTLA VQIRNYTFPL LSTAFGKCEG CLVLAQQATA FQPQIIHDVY IGRWRKVQML
RSASGTTPAM KTYLDLPIKF QKGEISFGIG YEPVLADISY AFTVALRRAN LSLKGPGLLQ
PPKKEKSLPW WDEMRNYVHG NVTLSFSETK WIVLGSPDPY EKLDKLHMTS GSVEIQQYDG
RVHFSAEDIK IFFSSFEGLA RHYPNSPVCP SSYPFLEVPR FSLEVRMDWE CESGSPLNHY
LFALPIEGKA RDKIYDPFRS TSLSLRWDFT LRPENPSVSA VDQTKKVGSE CKPEKSSFSP
PTINIGAHDL AWLIRFWNMN YLPPYKLRTF SRWPRFGVPR IPRSGNLSLD RVMTEYNLRL
DVTPICIKHM TLDSNNPAKG LTFDMTKLKY EICFSRGNQD FTFECKRETL DPVYQGIDLH
LPKAFLRRDQ HCSKPAQMSR TSSLSGSTDR VTSDNGTSTS DGTEKHPDDG FLFSSDYFTI
RRQAPKADPE RLMVWKEEGK IYREKVDARS TKEKQSEPEE NSHSDPSDDD GYNVVIADNC
QRIFVYGLKL LWNIENRDAV LSFAGGMSKA FQPPKPSPSR QYAQRKLLEG NQKHSESEVS
QDEPTKQPST GSGNLASQSK EPAEVLSPSS EPIKTENFAS FPLGATKTGD SNDPEEEGTR
HFMVNVVEPQ FNLHSEDING RFLLAAASGR VLARSFHSVV HVAYDMIEKA AQNENDHNPE
NGTDMTWTRM EVSMMLEHVQ AHVAPTDVDP GAGVQWLPKI RRSSPKAKRT GALLERVFMP
CDMYFQYTRH KGVTPDLKVK PLKELTFNSR NITASMTSRQ FQVMTDVLSN LLFARLPKAH
NDSLKLSGEE DDEVEEEIDE VVPDGIEEVE LAKIELEAKE RDRMMLLDDI RKLTQNESNS
GNINLEKESD FWMISGGRPV LVERLRKAYL SVQQSRKTAY TALRTSVKNA AELRLLEKDK
NKRPSSAMRI SLQINKVIWS MVLDGKTFAE VEIDNMIYDF NRDYRDIGIA QFTTRYVVLR
NCLPNAKCDT VLSAWNPPPE WGKKVMLQVD ARQGAPKDGQ APYELFQVEI YPLKIHLTET
MYTMMWEYIF PGEEQHSQRR EEVWKVSTTS GSRRRKGSFA QEAAALLAAS DLGQGSKNQS
LKSSTIRGSG RELRRTSSFD RSWEETVAES VATELVLSSM EHQGESSKGK LKDSKTSKAG
GRSVHEEKKG EKSLEDKKSR PQKIMQFQTI KISQVELLIT YEGSRFVVND MKLCMDTFHR
VEFSGTWRRL FSRVKKHIIW GVLKSVTGMQ MKKFKDKAHV PKDDIGLRDK DESGRTDQES
GAWVKRPGDN AGDGFVTSIR GIFNTQRRKA KKFVLRTMRG EAEDNFPGEW SDNESDFSPF
ARQLTITKAK KLIRRHSKKF QNQNTTKGSK KTQLSPTLSP PKEEDQYESD SSSGSSAYEE
FLDQNQI
