KISHA_CHICK
ID KISHA_CHICK Reviewed; 72 AA.
AC Q5ZII6;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Protein kish-A;
DE AltName: Full=Transmembrane protein 167;
DE AltName: Full=Transmembrane protein 167A;
DE Flags: Precursor;
GN Name=TMEM167A; Synonyms=TMEM167; ORFNames=RCJMB04_25n4;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Involved in the early part of the secretory pathway.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type I membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KISH family. {ECO:0000305}.
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DR EMBL; AJ720798; CAG32457.1; -; mRNA.
DR RefSeq; NP_001106925.1; NM_001113454.2.
DR AlphaFoldDB; Q5ZII6; -.
DR STRING; 9031.ENSGALP00000043412; -.
DR PaxDb; Q5ZII6; -.
DR GeneID; 770790; -.
DR KEGG; gga:770790; -.
DR CTD; 153339; -.
DR VEuPathDB; HostDB:geneid_770790; -.
DR eggNOG; KOG3808; Eukaryota.
DR HOGENOM; CLU_152663_1_1_1; -.
DR InParanoid; Q5ZII6; -.
DR OrthoDB; 1596132at2759; -.
DR PhylomeDB; Q5ZII6; -.
DR PRO; PR:Q5ZII6; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046907; P:intracellular transport; IBA:GO_Central.
DR GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR InterPro; IPR009653; Ksh1.
DR Pfam; PF06842; DUF1242; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..72
FT /note="Protein kish-A"
FT /id="PRO_0000247771"
FT TOPO_DOM 27..53
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 72
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 72 AA; 8004 MW; 46CBE7E8E4FD9A5B CRC64;
MSAIFNFQSL LTVILLLICT CAYIRSLAPS LLDKNKTGLL GIFWKCARIG ERKSPYVAVC
CVVMAFSILF VQ