KISHA_DANRE
ID KISHA_DANRE Reviewed; 72 AA.
AC Q5BJC2;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Protein kish-A;
DE AltName: Full=Transmembrane protein 167;
DE AltName: Full=Transmembrane protein 167A;
DE Flags: Precursor;
GN Name=tmem167a; Synonyms=tmem167; ORFNames=zgc:112458;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the early part of the secretory pathway.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type I membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KISH family. {ECO:0000305}.
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DR EMBL; BC091541; AAH91541.1; -; mRNA.
DR RefSeq; NP_001018875.2; NM_001023581.2.
DR AlphaFoldDB; Q5BJC2; -.
DR STRING; 7955.ENSDARP00000118932; -.
DR PaxDb; Q5BJC2; -.
DR GeneID; 541340; -.
DR KEGG; dre:541340; -.
DR CTD; 153339; -.
DR ZFIN; ZDB-GENE-050320-29; tmem167a.
DR eggNOG; KOG3808; Eukaryota.
DR InParanoid; Q5BJC2; -.
DR OrthoDB; 1596132at2759; -.
DR PhylomeDB; Q5BJC2; -.
DR PRO; PR:Q5BJC2; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046907; P:intracellular transport; IBA:GO_Central.
DR GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR InterPro; IPR009653; Ksh1.
DR Pfam; PF06842; DUF1242; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..72
FT /note="Protein kish-A"
FT /id="PRO_0000247772"
FT TOPO_DOM 27..53
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 72
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 72 AA; 8099 MW; 5B0281AB15EDD4AA CRC64;
MSAIFNFQSL LTVILLLICT CAYIRSLTPS LLDKNKTGFL GIFWKCARIG ERKSPYVAFC
CIVMALTILF SE