KISHA_TAEGU
ID KISHA_TAEGU Reviewed; 72 AA.
AC B5G2S6;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Protein kish-A;
DE AltName: Full=Transmembrane protein 167A;
DE Flags: Precursor;
GN Name=TMEM167A;
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=17018643; DOI=10.1073/pnas.0607098103;
RA Wada K., Howard J.T., McConnell P., Whitney O., Lints T., Rivas M.V.,
RA Horita H., Patterson M.A., White S.A., Scharff C., Haesler S., Zhao S.,
RA Sakaguchi H., Hagiwara M., Shiraki T., Hirozane-Kishikawa T., Skene P.,
RA Hayashizaki Y., Carninci P., Jarvis E.D.;
RT "A molecular neuroethological approach for identifying and characterizing a
RT cascade of behaviorally regulated genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15212-15217(2006).
CC -!- FUNCTION: Involved in the early part of the secretory pathway.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type I membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KISH family. {ECO:0000305}.
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DR EMBL; DQ216283; ACH45587.1; -; mRNA.
DR RefSeq; NP_001232051.1; NM_001245122.1.
DR AlphaFoldDB; B5G2S6; -.
DR STRING; 59729.ENSTGUP00000037480; -.
DR Ensembl; ENSTGUT00000035391; ENSTGUP00000037480; ENSTGUG00000019292.
DR GeneID; 100190468; -.
DR KEGG; tgu:100190468; -.
DR CTD; 153339; -.
DR GeneTree; ENSGT00940000155186; -.
DR InParanoid; B5G2S6; -.
DR OrthoDB; 1596132at2759; -.
DR Proteomes; UP000007754; Chromosome Z.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0045054; P:constitutive secretory pathway; IEA:Ensembl.
DR InterPro; IPR009653; Ksh1.
DR Pfam; PF06842; DUF1242; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..72
FT /note="Protein kish-A"
FT /id="PRO_0000367273"
FT TOPO_DOM 27..53
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 72
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 72 AA; 8022 MW; 46DFB7ECB5B88A5B CRC64;
MSAIFNFQSL LTVILLLICT CAYIRSLAPS LLDKNKSGLL GIFWKCARIG ERKSPYVAVC
CVVMAFSILF MQ