ID   KISHA_XENTR             Reviewed;          72 AA.
AC   Q28FL7; A4QND4;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Protein kish-A;
DE   AltName: Full=Transmembrane protein 167;
DE   AltName: Full=Transmembrane protein 167A;
DE   Flags: Precursor;
GN   Name=tmem167a; Synonyms=tmem167; ORFNames=TNeu030j15.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the early part of the secretory pathway.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC       pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KISH family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAJ82352.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR761906; CAJ82352.1; ALT_INIT; mRNA.
DR   EMBL; BC135460; AAI35461.1; -; mRNA.
DR   RefSeq; NP_001016167.1; NM_001016167.2.
DR   AlphaFoldDB; Q28FL7; -.
DR   STRING; 8364.ENSXETP00000011296; -.
DR   PaxDb; Q28FL7; -.
DR   DNASU; 548921; -.
DR   GeneID; 548921; -.
DR   KEGG; xtr:548921; -.
DR   CTD; 153339; -.
DR   Xenbase; XB-GENE-943966; tmem167a.
DR   eggNOG; KOG3808; Eukaryota.
DR   HOGENOM; CLU_152663_1_1_1; -.
DR   InParanoid; Q28FL7; -.
DR   OMA; VGCFMMG; -.
DR   OrthoDB; 1596132at2759; -.
DR   PhylomeDB; Q28FL7; -.
DR   TreeFam; TF300138; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027813; Expressed in embryo and 16 other tissues.
DR   ExpressionAtlas; Q28FL7; baseline.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046907; P:intracellular transport; IBA:GO_Central.
DR   GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR   InterPro; IPR009653; Ksh1.
DR   Pfam; PF06842; DUF1242; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..72
FT                   /note="Protein kish-A"
FT                   /id="PRO_0000247773"
FT   TOPO_DOM        27..53
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        72
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        35
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   72 AA;  8087 MW;  F1EAFDCF02FB07CB CRC64;
     MSAIFNFQSL LIVILLLICT CAYLRALVPN LLDKNKTGIL GIFWKCARIG ERKSPYVAVC
     CVVMAFSILF MQ