KISHB_DANRE
ID KISHB_DANRE Reviewed; 74 AA.
AC Q6AZW1;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Protein kish-B;
DE AltName: Full=Transmembrane protein 167B;
DE Flags: Precursor;
GN Name=tmem167b; ORFNames=zgc:101127;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the early part of the secretory pathway.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type I membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KISH family. {ECO:0000305}.
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DR EMBL; BC077152; AAH77152.1; -; mRNA.
DR RefSeq; NP_001003761.1; NM_001003761.2.
DR AlphaFoldDB; Q6AZW1; -.
DR STRING; 7955.ENSDARP00000076947; -.
DR PaxDb; Q6AZW1; -.
DR Ensembl; ENSDART00000082512; ENSDARP00000076947; ENSDARG00000059400.
DR GeneID; 445304; -.
DR KEGG; dre:445304; -.
DR CTD; 56900; -.
DR ZFIN; ZDB-GENE-040808-17; tmem167b.
DR eggNOG; KOG3808; Eukaryota.
DR GeneTree; ENSGT00940000162196; -.
DR HOGENOM; CLU_152663_1_2_1; -.
DR InParanoid; Q6AZW1; -.
DR OMA; CTCAYMS; -.
DR OrthoDB; 1596132at2759; -.
DR PhylomeDB; Q6AZW1; -.
DR TreeFam; TF300138; -.
DR PRO; PR:Q6AZW1; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 11.
DR Bgee; ENSDARG00000059400; Expressed in caudal fin and 27 other tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR042863; Kish-B.
DR InterPro; IPR009653; Ksh1.
DR PANTHER; PTHR46815; PTHR46815; 1.
DR Pfam; PF06842; DUF1242; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..74
FT /note="Protein kish-B"
FT /id="PRO_0000265084"
FT TOPO_DOM 23..52
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 74 AA; 8342 MW; BF7C7B862DA58BC7 CRC64;
MTNVYSFDGI LVFGLLFICT CAYLKKVPRL NSWLLSEKKG VWGVFYKAAV IGTRLHVVVA
ASCLCMAFYL IFLK