ID   ARAB_STAEQ              Reviewed;         536 AA.
AC   Q5HLQ6;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Ribulokinase {ECO:0000255|HAMAP-Rule:MF_00520};
DE            EC=2.7.1.16 {ECO:0000255|HAMAP-Rule:MF_00520};
GN   Name=araB {ECO:0000255|HAMAP-Rule:MF_00520}; OrderedLocusNames=SERP1927;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribulose = ADP + D-ribulose 5-phosphate + H(+);
CC         Xref=Rhea:RHEA:17601, ChEBI:CHEBI:15378, ChEBI:CHEBI:17173,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58121, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC         Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC       ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC       step 2/3. {ECO:0000255|HAMAP-Rule:MF_00520}.
CC   -!- SIMILARITY: Belongs to the ribulokinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00520}.
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DR   EMBL; CP000029; AAW55269.1; -; Genomic_DNA.
DR   RefSeq; WP_002438418.1; NC_002976.3.
DR   AlphaFoldDB; Q5HLQ6; -.
DR   SMR; Q5HLQ6; -.
DR   STRING; 176279.SERP1927; -.
DR   EnsemblBacteria; AAW55269; AAW55269; SERP1927.
DR   KEGG; ser:SERP1927; -.
DR   eggNOG; COG1069; Bacteria.
DR   HOGENOM; CLU_009281_9_1_9; -.
DR   OMA; RPRENHA; -.
DR   OrthoDB; 1619686at2; -.
DR   UniPathway; UPA00145; UER00566.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019150; F:D-ribulokinase activity; IEA:RHEA.
DR   GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniRule.
DR   CDD; cd07781; FGGY_RBK; 1.
DR   HAMAP; MF_00520; Ribulokinase; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005929; Ribulokinase.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Arabinose catabolism; ATP-binding; Carbohydrate metabolism; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..536
FT                   /note="Ribulokinase"
FT                   /id="PRO_0000198373"
SQ   SEQUENCE   536 AA;  60092 MW;  30C27F7C381AF443 CRC64;
     MSYSIGIDFG TASGRVILAD TSNGHIISRY EEDYANGTYM NSLYDKPLPE NYFLQNADDY
     LQILEQGVQF VLEDSKVNKN DVVGIGVDFT SSTIIFLDEQ FEPLHRHEDL KTNPHAYVKL
     WKHHGAQDEA NYMIQMSKNK NWLDYYGSSV NSEWMIPKIL EVKHEAPEIL RRARYIMEAG
     DYITSILTNS NIRSNCGIGF KGFWDNEAGF NYDFFHSVDP DLPKIVKEKC EAPIISIGES
     AGRLCKDYQQ IWGLSQDVQV SPFIIDAHSG VLGVGAIEAG EFTAVIGTST CHLMLDSRQV
     PISSITGSVK NAIIPGLYAY EAGQPAVGDL FEYSKNQAPK HIVDQANEHH MHVLNYLEEL
     ASHIRIEEQH VVVLDWLNGN RSILSNSHLT GSIFGLTLQT PYEMIHRAYI EATAFGTKLI
     MKQFEDNHIP VHTVYASGGI PQKSKLLVEI YANVLNKRVV VIDSSNASAL GAAMLGANVG
     NAYSTLKEAA LSMKQPIAYI QEPEIQKVQA YKPLYHKYCE LHDLLGRQYP ELSYLI