ARAB_YERPE
ID ARAB_YERPE Reviewed; 563 AA.
AC P58543; Q0WER7;
DT 23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Ribulokinase {ECO:0000255|HAMAP-Rule:MF_00520};
DE EC=2.7.1.16 {ECO:0000255|HAMAP-Rule:MF_00520};
GN Name=araB {ECO:0000255|HAMAP-Rule:MF_00520};
GN OrderedLocusNames=YPO2254, y2095, YP_2050;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-ribulose = ADP + D-ribulose 5-phosphate + H(+);
CC Xref=Rhea:RHEA:17601, ChEBI:CHEBI:15378, ChEBI:CHEBI:17173,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58121, ChEBI:CHEBI:456216;
CC EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC step 2/3. {ECO:0000255|HAMAP-Rule:MF_00520}.
CC -!- SIMILARITY: Belongs to the ribulokinase family. {ECO:0000255|HAMAP-
CC Rule:MF_00520}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM85658.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAS62264.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAL20881.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL590842; CAL20881.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE009952; AAM85658.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE017042; AAS62264.1; ALT_INIT; Genomic_DNA.
DR PIR; AF0274; AF0274.
DR RefSeq; YP_002347221.1; NC_003143.1.
DR AlphaFoldDB; P58543; -.
DR SMR; P58543; -.
DR IntAct; P58543; 6.
DR STRING; 214092.YPO2254; -.
DR PaxDb; P58543; -.
DR DNASU; 1147042; -.
DR EnsemblBacteria; AAM85658; AAM85658; y2095.
DR EnsemblBacteria; AAS62264; AAS62264; YP_2050.
DR KEGG; ype:YPO2254; -.
DR KEGG; ypk:y2095; -.
DR KEGG; ypm:YP_2050; -.
DR PATRIC; fig|214092.21.peg.2650; -.
DR eggNOG; COG1069; Bacteria.
DR HOGENOM; CLU_009281_9_1_6; -.
DR UniPathway; UPA00145; UER00566.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019150; F:D-ribulokinase activity; IBA:GO_Central.
DR GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046835; P:carbohydrate phosphorylation; IBA:GO_Central.
DR GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniRule.
DR GO; GO:0019321; P:pentose metabolic process; IBA:GO_Central.
DR CDD; cd07781; FGGY_RBK; 1.
DR HAMAP; MF_00520; Ribulokinase; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018485; Carb_kinase_FGGY_C.
DR InterPro; IPR005929; Ribulokinase.
DR Pfam; PF02782; FGGY_C; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR TIGRFAMs; TIGR01234; L-ribulokinase; 1.
PE 3: Inferred from homology;
KW Arabinose catabolism; ATP-binding; Carbohydrate metabolism; Kinase;
KW Nucleotide-binding; Reference proteome; Transferase.
FT CHAIN 1..563
FT /note="Ribulokinase"
FT /id="PRO_0000198377"
SQ SEQUENCE 563 AA; 61833 MW; 88EF1E0B00A5414E CRC64;
MISADGAIAL GLDFGSDSVR VLAVDCQHGT EIDTEVVYYP RWKKGLYCQA AQNQFRHHPL
DYIEAMEQAI RQMVKRLSEE QRQHIVGIGV DSTGSTPAPI DEQGQVLALR PDFADNPNAM
FVLWKDHTAI EEAEEINRLC RSGEFADYSR YIGGVYSSEW FWAKILHVTR ADVAVREAAV
SWIELCDWVP ALLSGTTAPQ DIQRGRCSAG HKSLWHPSWG GLPPRAFLAA LDTSLVNDLD
YPMFTDTYTA ERPVGQITAE WAERLGLPTT VILSGGAFDC HMGAVGAGAQ PYTLVKVIGT
STCDILIADD QRVGDRAIAG ICGQVEGSVL PGWIGMEAGQ SAFGDMYAWF SNLLSWPLHQ
AALTQPEWQP QLKQIESNLL ASLTRAWAQN PSLDHLPVVL DWFNGRRTPN ANQRLKGVIT
DLNLGTDAPT LFGGFIAATA FGARAIMECF EQQDIPIDNV LALGGIARKS PVIMQVCADV
MNRPLQIVAS DQCCALGAAI FAAVAAGAHD DVPTAQRHMA CNIERTLIPD PVQVVRYQQL
YQRYQQWCHT AEPHYAPVTK VIH
