ID   KLC4_BOVIN              Reviewed;         616 AA.
AC   Q2HJJ0;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Kinesin light chain 4;
DE            Short=KLC 4;
DE   AltName: Full=Kinesin-like protein 8;
GN   Name=KLC4; Synonyms=KNSL8;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Kinesin is a microtubule-associated force-producing protein
CC       that may play a role in organelle transport. The light chain may
CC       function in coupling of cargo to the heavy chain or in the modulation
CC       of its ATPase activity (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Oligomeric complex composed of two heavy chains and two light
CC       chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the kinesin light chain family. {ECO:0000305}.
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DR   EMBL; BC105320; AAI05321.1; -; mRNA.
DR   RefSeq; XP_015315329.1; XM_015459843.1.
DR   AlphaFoldDB; Q2HJJ0; -.
DR   SMR; Q2HJJ0; -.
DR   STRING; 9913.ENSBTAP00000016955; -.
DR   PaxDb; Q2HJJ0; -.
DR   eggNOG; KOG1840; Eukaryota.
DR   InParanoid; Q2HJJ0; -.
DR   OrthoDB; 511880at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002151; Kinesin_light.
DR   InterPro; IPR015792; Kinesin_light_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PRINTS; PR00381; KINESINLIGHT.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; SSF48452; 2.
DR   PROSITE; PS01160; KINESIN_LIGHT; 2.
DR   PROSITE; PS50005; TPR; 6.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   2: Evidence at transcript level;
KW   Acetylation; Coiled coil; Cytoplasm; Cytoskeleton; Microtubule;
KW   Motor protein; Phosphoprotein; Reference proteome; Repeat; TPR repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NSK0"
FT   CHAIN           2..616
FT                   /note="Kinesin light chain 4"
FT                   /id="PRO_0000384581"
FT   REPEAT          55..88
FT                   /note="TPR 1"
FT   REPEAT          208..241
FT                   /note="TPR 2"
FT   REPEAT          250..283
FT                   /note="TPR 3"
FT   REPEAT          292..325
FT                   /note="TPR 4"
FT   REPEAT          334..367
FT                   /note="TPR 5"
FT   REPEAT          376..409
FT                   /note="TPR 6"
FT   REPEAT          461..494
FT                   /note="TPR 7"
FT   REGION          160..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          507..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          597..616
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          32..150
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        160..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NSK0"
FT   MOD_RES         174
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DBS5"
FT   MOD_RES         457
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NSK0"
FT   MOD_RES         516
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q07866"
FT   MOD_RES         562
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5PQM2"
FT   MOD_RES         563
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NSK0"
FT   MOD_RES         587
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NSK0"
SQ   SEQUENCE   616 AA;  68220 MW;  9000CEBF3380D9DB CRC64;
     MSGLVLGQRD EPAGHRLSQE EILGSTRLVS QGLEALHSEH QAVLQSLSQT IECLQQGGHE
     EGLVHEKARQ LRRSMENIEL GLSEAQVMLA LANHLSTVES EKQKLRAQVR RLCQENQWLR
     DELAGTQQRL QRSEQAVAQL EEEKKHLEFL GQLRQYDEDG HAAEEKEGDA SKDSLDDLFP
     NEEEEDPSNG LSRGQGAQHS GYEIPARLRT LHNLVIQYAA QGRYEVAVPL CKQALEDLER
     TSGRGHPVVA TMLNILALVY RGQNKYKEAA LLLNDALSIR ESTLGRDHPA VAATLNNLAV
     LYGKRGKYKE AEPLCQRALE IREKVLGTNH PDVAKQLNNL ALLCQNQGKY EAVERYYRRA
     LAIYEGQLGP DNPNVARTKN NLASCYLKQG KYAEAETLYK EILTRAHVQE FGSVDDDHKP
     IWMHAEEREE MSKIRHREGS TPYAEYGGWY KACKVSSPTV NTTLRNLGAL YRRQGKLEAA
     ETLEECALRS RKQGTDPISQ TKVAELLGEG DSGRTSQEGL GGSVKFEGGE DASVAVEWSG
     DGSGALQRSG SLGKIRDVLR RSSELLVRKL QGSEPRPSSS NMKRAASLNY LNQPSAAPLQ
     VSRGLSASSM DLSSSS