KLCR2_ARATH
ID KLCR2_ARATH Reviewed; 663 AA.
AC Q9LII8; Q7XA91;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Protein KINESIN LIGHT CHAIN-RELATED 2 {ECO:0000303|PubMed:23204523};
DE AltName: Full=Kinesin light chain-like protein 1 {ECO:0000303|Ref.1};
DE Short=AtKLC1 {ECO:0000303|Ref.1};
GN Name=KLCR2 {ECO:0000303|PubMed:23204523};
GN Synonyms=KLC1 {ECO:0000303|Ref.1};
GN OrderedLocusNames=At3g27960 {ECO:0000312|Araport:AT3G27960};
GN ORFNames=K24A2.5 {ECO:0000312|EMBL:BAB01483.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Leivar P., Boronat A., Campos N.;
RT "Kinesin light chain-like protein from Arabidopsis thaliana.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=23204523; DOI=10.1074/jbc.m112.396200;
RA Buerstenbinder K., Savchenko T., Mueller J., Adamson A.W., Stamm G.,
RA Kwong R., Zipp B.J., Dinesh D.C., Abel S.;
RT "Arabidopsis calmodulin-binding protein IQ67-domain 1 localizes to
RT microtubules and interacts with kinesin light chain-related protein-1.";
RL J. Biol. Chem. 288:1871-1882(2013).
CC -!- SIMILARITY: Belongs to the kinesin light chain family. {ECO:0000305}.
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DR EMBL; AY462123; AAS44558.1; -; mRNA.
DR EMBL; AP001302; BAB01483.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77386.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM63950.1; -; Genomic_DNA.
DR EMBL; BT010128; AAQ22597.1; -; mRNA.
DR EMBL; AK227461; BAE99464.1; -; mRNA.
DR RefSeq; NP_001326010.1; NM_001338927.1.
DR RefSeq; NP_189435.1; NM_113713.4.
DR AlphaFoldDB; Q9LII8; -.
DR SMR; Q9LII8; -.
DR IntAct; Q9LII8; 74.
DR STRING; 3702.AT3G27960.1; -.
DR iPTMnet; Q9LII8; -.
DR PaxDb; Q9LII8; -.
DR PRIDE; Q9LII8; -.
DR ProteomicsDB; 230372; -.
DR EnsemblPlants; AT3G27960.1; AT3G27960.1; AT3G27960.
DR EnsemblPlants; AT3G27960.3; AT3G27960.3; AT3G27960.
DR GeneID; 822420; -.
DR Gramene; AT3G27960.1; AT3G27960.1; AT3G27960.
DR Gramene; AT3G27960.3; AT3G27960.3; AT3G27960.
DR KEGG; ath:AT3G27960; -.
DR Araport; AT3G27960; -.
DR TAIR; locus:2086834; AT3G27960.
DR eggNOG; KOG1840; Eukaryota.
DR HOGENOM; CLU_021284_1_0_1; -.
DR InParanoid; Q9LII8; -.
DR OMA; IGQIENS; -.
DR OrthoDB; 320145at2759; -.
DR PhylomeDB; Q9LII8; -.
DR PRO; PR:Q9LII8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LII8; baseline and differential.
DR GO; GO:0009860; P:pollen tube growth; IEP:TAIR.
DR GO; GO:0031347; P:regulation of defense response; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR041617; TPR_MalT.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF17874; TPR_MalT; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50005; TPR; 8.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..663
FT /note="Protein KINESIN LIGHT CHAIN-RELATED 2"
FT /id="PRO_0000438248"
FT REPEAT 147..181
FT /note="TPR 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 200..233
FT /note="TPR 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 243..276
FT /note="TPR 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 285..318
FT /note="TPR 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 329..363
FT /note="TPR 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 369..402
FT /note="TPR 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 411..444
FT /note="TPR 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 454..487
FT /note="TPR 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 495..528
FT /note="TPR 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 537..570
FT /note="TPR 10"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 579..612
FT /note="TPR 11"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 19
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT CONFLICT 224
FT /note="E -> G (in Ref. 4; AAQ22597 and 5; BAE99464)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 663 AA; 72515 MW; 146BE6A373E66B8D CRC64;
MDVGESNERV KDDSALQASP RSPLSSIDLA IDGAMNASIE QLYHNVCEME SSDDQSPSRA
SFISYGAESR IDLELRHLVG DVGEEGESKK EIILEKKEES NGEGSLSQKK PLSNGKKVAK
TSPNNPKMPG SRISSRKSPD LGKVSVDEES PELGVVLLKQ ARELVSSGEN LNKALDLALR
AVKVFEKCGE GEKQLGLNLV MSLHILAAIY AGLGRYNDAV PVLERSIEIP MIEDGEDHAL
AKFAGCMQLG DMYGLMGQVE NSIMLYTAGL EIQRQVLGES DARVGETCRY LAEAHVQAMQ
FEEASRLCQM ALDIHKENGA AATASIEEAA DRKLMGLICD AKGDYEVALE HYVLASMAMS
SQNHREDVAA VDCSIGDAYM SLARFDEAIF AYQKALAVFK QGKGETHSSV ALVYVRLADL
YNKIGKTRDS KSYCENALKI YLKPTPGTPM EEVATGFIEI SAIYQSMNEL DQALKLLRRA
LKIYANAPGQ QNTIAGIEAQ MGVVTYMMGN YSESYDIFKS AISKFRNSGE KKTALFGIAL
NQMGLACVQR YAINEAADLF EEAKTILEKE CGPYHPDTLA VYSNLAGTYD AMGRLDDAIE
ILEYVVGTRE EKLGTANPEV EDEKQRLAAL LKEAGRGRSK RNRALLTLLD NNPEIANGQR
PVY
