ID   KLH23_PONAB             Reviewed;         558 AA.
AC   Q5RCQ9;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Kelch-like protein 23;
GN   Name=KLHL23;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CR858210; CAH90448.1; -; mRNA.
DR   RefSeq; NP_001125228.1; NM_001131756.1.
DR   AlphaFoldDB; Q5RCQ9; -.
DR   SMR; Q5RCQ9; -.
DR   STRING; 9601.ENSPPYP00000014417; -.
DR   GeneID; 100172121; -.
DR   KEGG; pon:100172121; -.
DR   CTD; 151230; -.
DR   eggNOG; KOG4441; Eukaryota.
DR   InParanoid; Q5RCQ9; -.
DR   Proteomes; UP000001595; Unplaced.
DR   Gene3D; 2.120.10.80; -; 2.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..558
FT                   /note="Kelch-like protein 23"
FT                   /id="PRO_0000242159"
FT   DOMAIN          36..104
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          139..240
FT                   /note="BACK"
FT   REPEAT          274..320
FT                   /note="Kelch 1"
FT   REPEAT          321..369
FT                   /note="Kelch 2"
FT   REPEAT          370..416
FT                   /note="Kelch 3"
FT   REPEAT          418..466
FT                   /note="Kelch 4"
FT   REPEAT          467..508
FT                   /note="Kelch 5"
FT   REPEAT          510..557
FT                   /note="Kelch 6"
SQ   SEQUENCE   558 AA;  63830 MW;  78D21B3029C8E2F9 CRC64;
     MALKGQEDYI YLFKDSTHPV DFLDAFRTFY LDGLFTDITL QCPSGIIFHC HRAVLAACSN
     YFKAMFTADM KEKFKNKIKL SGIHHDILEG LVNYAYTSQI EITERNVQSL LEAADLLQFL
     SVKKACERFL VRHLDIDNCI GMHSFAEFHV CPELEKESRR ILCSKFKEVW QQEEFLEISL
     EKFLFILSRK NLSVWKEEAI IEPVIKWTAH DVENRIECLC NLLSYINIDV DPVYLKTALG
     LQRSCLFTEN KIRSLIYNAL NPMHKEISQR STATMYIIGG YYWHPLSEVH IWDPLTNVWI
     QGAEIPDYTR ESYGVTCLGP NIYVTGGYRT DNIEALDTVW IYNSESDEWT EGLPTLNARY
     YHCAVTLGGC VYALGGYRKG APAEEAEFYD PLKEKWIPIA NMIKGVGNAT ACVLHDVIYV
     IGGHCGYRGS CTYDKVQSYN SDINEWSLIT SSPHPEYGLC SVPLENKLYL VGGQTTITEC
     YDPEQNEWRE IAPMMERRME CGAVIMNGCI YVTGGYPYSK GTYLQSIEKY DPDLNKWEIV
     GNLPSAMRSH GCVCVYNV