KLH26_DANRE
ID KLH26_DANRE Reviewed; 605 AA.
AC Q5RGB8;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Kelch-like protein 26;
GN Name=klhl26; ORFNames=si:ch211-255d18.7;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX936438; CAI11912.1; -; Genomic_DNA.
DR RefSeq; XP_009304087.1; XM_009305812.2.
DR AlphaFoldDB; Q5RGB8; -.
DR SMR; Q5RGB8; -.
DR STRING; 7955.ENSDARP00000070477; -.
DR PaxDb; Q5RGB8; -.
DR Ensembl; ENSDART00000075998; ENSDARP00000070477; ENSDARG00000053876.
DR Ensembl; ENSDART00000144181; ENSDARP00000115562; ENSDARG00000053876.
DR ZFIN; ZDB-GENE-030131-5975; klhl26.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000159238; -.
DR HOGENOM; CLU_004253_14_3_1; -.
DR InParanoid; Q5RGB8; -.
DR OMA; CPKDNEW; -.
DR PhylomeDB; Q5RGB8; -.
DR TreeFam; TF328485; -.
DR PRO; PR:Q5RGB8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 11.
DR Bgee; ENSDARG00000053876; Expressed in testis and 23 other tissues.
DR ExpressionAtlas; Q5RGB8; baseline.
DR Gene3D; 2.120.10.80; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030588; KLHL26.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF13; PTHR45632:SF13; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..605
FT /note="Kelch-like protein 26"
FT /id="PRO_0000242690"
FT DOMAIN 53..120
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT DOMAIN 155..256
FT /note="BACK"
FT REPEAT 300..351
FT /note="Kelch 1"
FT REPEAT 352..403
FT /note="Kelch 2"
FT REPEAT 404..450
FT /note="Kelch 3"
FT REPEAT 452..498
FT /note="Kelch 4"
FT REPEAT 499..549
FT /note="Kelch 5"
FT REPEAT 551..598
FT /note="Kelch 6"
SQ SEQUENCE 605 AA; 68535 MW; 55AA538ADEA9699B CRC64;
MAESDGVEFF ANRAQSSMAD NKNSVLRCTF SAPSHSSTLL RGLSALRDQG QLLDVVLAID
NERFEVHKAV LASCSDYFRA MFTGGMKESN QNTIELIGLS ARGLKHIIDF AYSSEVTLDL
DCIQDVLGAA VFLQMVPVVE LCEEFLKSAM SVETCLNIGQ MATTFSLSSL KQSVDAYTFR
HFLQIAQEDD FLHIPMERLT FFLQSNKLKN CSEIDLFHAA IRWLQHDASR RTVASEVLCH
VRFPLMRSSE LVDSVQIVDI MVEDVQCRHF LLEAFNYQIL PFRQHEMQSP RTSIRSDITS
LITFGGTPYT DNDRTVSSKV YFLPDITVRQ FKELTEMEMG CSHACVSVLD NFVYVVGGQH
LQYRSGEGAV DICFRYDPHL NQWLRIQPMQ ESRIQFQLNV LDGQLYATGG RNRSGSLSSV
ECYCPKKNEW TNVDSLKRRI WGHAGATCGD KLYISGGYGV SVEDKKTLHC YDSALDQWDF
KCPMNEPRVL HAMISANNRI YALGGRMDHV DRCFDVLAVE YYIPETDQWT TVSPMRAGQS
EAGCCLLDKK IYIVGGYNWH LNNVTSIVQV YNTETDEWER DLHFPESFAG IACTPIILPQ
TTTQR
