ID   KLH30_XENLA             Reviewed;         589 AA.
AC   Q6INL2;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Kelch-like protein 30;
GN   Name=klhl30;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC072268; AAH72268.1; -; mRNA.
DR   RefSeq; NP_001085193.1; NM_001091724.1.
DR   AlphaFoldDB; Q6INL2; -.
DR   SMR; Q6INL2; -.
DR   DNASU; 432282; -.
DR   GeneID; 432282; -.
DR   KEGG; xla:432282; -.
DR   CTD; 432282; -.
DR   Xenbase; XB-GENE-1011189; klhl30.L.
DR   OMA; KAWAFLL; -.
DR   OrthoDB; 743142at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 432282; Expressed in heart and 5 other tissues.
DR   Gene3D; 2.120.10.80; -; 1.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR030582; KLHL30.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF398; PTHR24412:SF398; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 2.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 4.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..589
FT                   /note="Kelch-like protein 30"
FT                   /id="PRO_0000274596"
FT   DOMAIN          33..100
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          135..237
FT                   /note="BACK"
FT   REPEAT          274..335
FT                   /note="Kelch 1"
FT   REPEAT          336..386
FT                   /note="Kelch 2"
FT   REPEAT          387..431
FT                   /note="Kelch 3"
FT   REPEAT          433..480
FT                   /note="Kelch 4"
FT   REPEAT          482..522
FT                   /note="Kelch 5"
FT   REPEAT          523..572
FT                   /note="Kelch 6"
SQ   SEQUENCE   589 AA;  66442 MW;  3293ED8861705762 CRC64;
     MVRNIDDLEF CLPSHSDAIL SGLQTLRFNP RLSDVILVVQ GREFPCHRAV LALCSQYFHA
     MFTGDFQESI SAQVEIKEVD PEVMETLIDF SYTGRLTINQ GNVEGLIRTS NLLSFPAVRK
     VCSRYLQQQM DATNCLGIWE FGETHGCPEV AAKALSFLQE NFEAVSQEEE FLLLSPERML
     CYLGDPLLQV RDEQSRAKAA LHWVKQDKEC RAQCLPQLLS VAQLSSLTDQ YLQELMEVEP
     LISESEVCRT LIGKNLGQET RGLREQSPVF LQEVLVVVGG KVLEEEEEDE DEEDEETQRT
     SANFAYYNTK TKKWMAFPDF PDYNKWGFSI TSLSNDVYVT GGSRGSRDDS WSTRQGWRFV
     LNEGIWKPIT PMINPRTNHS SASLNGEIYV IGGTLQEAVE VECYDPYSGT WSLISPAQKY
     VSNFTAVGCS GKLYLIGSCA MKYNALTLQC YNPATDGWSV IASPFIPKYL SSPCCCTVGG
     SVYLIADNTK KVYMYLPEVN LWKKVQLLHT LHENGGMTSV GSCLYVTGGH WHGMARDYSV
     VMESYDCNTD VWTRQGPLPS PWLYHCTSTI FMDTSRWTEE FQGQPEAEL