ID   KLH38_RAT               Reviewed;         580 AA.
AC   Q5BK60;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Kelch-like protein 38;
GN   Name=Klhl38;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC091195; AAH91195.1; -; mRNA.
DR   RefSeq; NP_001020179.1; NM_001025008.1.
DR   RefSeq; XP_008763731.1; XM_008765509.1.
DR   AlphaFoldDB; Q5BK60; -.
DR   SMR; Q5BK60; -.
DR   STRING; 10116.ENSRNOP00000010484; -.
DR   PaxDb; Q5BK60; -.
DR   PRIDE; Q5BK60; -.
DR   Ensembl; ENSRNOT00000010484; ENSRNOP00000010484; ENSRNOG00000007896.
DR   GeneID; 314996; -.
DR   KEGG; rno:314996; -.
DR   UCSC; RGD:1564169; rat.
DR   CTD; 340359; -.
DR   RGD; 1564169; Klhl38.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000157647; -.
DR   InParanoid; Q5BK60; -.
DR   OMA; CLTLQCV; -.
DR   OrthoDB; 292812at2759; -.
DR   PhylomeDB; Q5BK60; -.
DR   TreeFam; TF329218; -.
DR   PRO; PR:Q5BK60; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000007896; Expressed in skeletal muscle tissue and 10 other tissues.
DR   Genevisible; Q5BK60; RN.
DR   Gene3D; 2.120.10.80; -; 2.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR030568; KLHL38.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF462; PTHR24412:SF462; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 4.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 5.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..580
FT                   /note="Kelch-like protein 38"
FT                   /id="PRO_0000325811"
FT   DOMAIN          34..101
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          136..237
FT                   /note="BACK"
FT   REPEAT          284..331
FT                   /note="Kelch 1"
FT   REPEAT          333..382
FT                   /note="Kelch 2"
FT   REPEAT          383..430
FT                   /note="Kelch 3"
FT   REPEAT          432..478
FT                   /note="Kelch 4"
FT   REPEAT          479..520
FT                   /note="Kelch 5"
FT   REPEAT          522..572
FT                   /note="Kelch 6"
SQ   SEQUENCE   580 AA;  65672 MW;  20E6268EE7059E44 CRC64;
     MDEELPDAVV FKDQNFSSDL LRQLNGLRQS KILTDVSICS GACEVPCHRN VLASSSPYFR
     AMFCSHFRES REAKVQLKGI SSTTLEQVIA YVYTGEVHIS AANVLPLMEA AAMLQYPRMF
     EACSSYLQSQ LAPSNCLGLV RLAEILSCDS LKKKAREVAL TYFPEVAASA DLKELCVMEL
     RDYLGDDKLC GEEEKVFEAL MAWVKHDLQA RWRYMQELLQ QVRLQYIHPA FFHHFIASDA
     LLQSSPACQA ILEMAKKQIF SLYGPSAQDC KLWHTPPRSS YQDFLLLLGG RKDNQQTTRD
     VLLYSIQTGQ WQSLAKLPTR LYKASAVTLH RSVYVLGGMA VREGKGLISC SVYIFSMKLN
     QWRMGEPMLA ARYSHRSTTH RNFIFSIGGT GEGQELLGSM ERYDSIRDVW ESMADMPMAV
     LHPAVAVKDQ RLYLFGGEDI MQNPVRLIQV YHISRNTWYK METRMIKNVC APAVVLGEKI
     IIVGGYTRRI LAYDPQSNKF VKCADMKDRR MHHGATVMGN KLYVTGGRRL TTDCNIEDSA
     SFDCYDPETD TWTSQGQLPH TLFDHACLTL QCIPHMTSLS