ID   ARAG_ALKHC              Reviewed;         517 AA.
AC   Q9K7C3;
DT   03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=L-arabinose transport ATP-binding protein AraG;
DE            EC=7.5.2.12;
GN   Name=araG; OrderedLocusNames=BH3441;
OS   Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for L-
CC       arabinose. Probably responsible for energy coupling to the transport
CC       system (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + L-arabinose(out) = ADP + H(+) + L-arabinose(in) +
CC         phosphate; Xref=Rhea:RHEA:30007, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17535, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.12;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; BA000004; BAB07160.1; -; Genomic_DNA.
DR   PIR; A84080; A84080.
DR   AlphaFoldDB; Q9K7C3; -.
DR   SMR; Q9K7C3; -.
DR   STRING; 272558.10176064; -.
DR   EnsemblBacteria; BAB07160; BAB07160; BAB07160.
DR   KEGG; bha:BH3441; -.
DR   eggNOG; COG1129; Bacteria.
DR   HOGENOM; CLU_000604_92_3_9; -.
DR   OMA; LPGGRMH; -.
DR   PRO; PR:Q9K7C3; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015612; F:ABC-type L-arabinose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Repeat; Sugar transport; Translocase; Transport.
FT   CHAIN           1..517
FT                   /note="L-arabinose transport ATP-binding protein AraG"
FT                   /id="PRO_0000091934"
FT   DOMAIN          8..245
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          264..510
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         40..47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         309..316
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   517 AA;  57148 MW;  B95DD8FE4027B1BC CRC64;
     MNMPNCLLEM RNITKAFPGV KALNNVNLKV EQGEIHALVG ENGAGKSTLM KVLSGVYPHG
     TYEGDILFEG RVCQFKDIKE SEQLGIVIIH QELALVPELS IAENIFLGNE QAKNGVIDWN
     QTITEAAKLL KKVGLSDSPR TLAMNIGVGK QQLVEIAKAL SKKVKLLILD EPTAALNEED
     SQNLLHLLLE FKKQGMTSII ISHKLNEISY VADHLTILRD GQSIETLSLQ SGEVTEDRII
     KGMVGRDLEN RFPPREPKIG DVILEVNHWH VDDPLHPDRS LIKDVNLYLK RGEIVGVAGL
     MGAGRTELAM SIFGKSYGKN IRGQLIKDGK EIKVHSVKDA IDHGLAYVTE DRKTYGLILI
     DDIKHNISLT SLEKLSKNGV VDKTREVKEA EDFRKKMNIR TPSIDQKTGN LSGGNQQKVV
     LSKWILSGPD ILILDEPTRG IDVGAKYEIY SVIHELAAQG KAVLVISSEL PELLGLSDRI
     YALCEGRITG EVTREEANQE ILMKYMTRTG GNGHEVS