ID   ARAG_BURMA              Reviewed;         503 AA.
AC   Q62GY9;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Arabinose import ATP-binding protein AraG {ECO:0000255|HAMAP-Rule:MF_01721};
DE            EC=7.5.2.12 {ECO:0000255|HAMAP-Rule:MF_01721};
GN   Name=araG {ECO:0000255|HAMAP-Rule:MF_01721}; OrderedLocusNames=BMA2485;
OS   Burkholderia mallei (strain ATCC 23344).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=243160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23344;
RX   PubMed=15377793; DOI=10.1073/pnas.0403306101;
RA   Nierman W.C., DeShazer D., Kim H.S., Tettelin H., Nelson K.E.,
RA   Feldblyum T.V., Ulrich R.L., Ronning C.M., Brinkac L.M., Daugherty S.C.,
RA   Davidsen T.D., DeBoy R.T., Dimitrov G., Dodson R.J., Durkin A.S.,
RA   Gwinn M.L., Haft D.H., Khouri H.M., Kolonay J.F., Madupu R., Mohammoud Y.,
RA   Nelson W.C., Radune D., Romero C.M., Sarria S., Selengut J., Shamblin C.,
RA   Sullivan S.A., White O., Yu Y., Zafar N., Zhou L., Fraser C.M.;
RT   "Structural flexibility in the Burkholderia mallei genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14246-14251(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex AraFGH involved in
CC       arabinose import. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01721}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + L-arabinose(out) = ADP + H(+) + L-arabinose(in) +
CC         phosphate; Xref=Rhea:RHEA:30007, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17535, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.12;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01721};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (AraG),
CC       two transmembrane proteins (AraH) and a solute-binding protein (AraF).
CC       {ECO:0000255|HAMAP-Rule:MF_01721}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01721}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01721}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Arabinose
CC       importer (TC 3.A.1.2.2) family. {ECO:0000255|HAMAP-Rule:MF_01721}.
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DR   EMBL; CP000010; AAU50164.1; -; Genomic_DNA.
DR   RefSeq; WP_004194122.1; NC_006348.1.
DR   RefSeq; YP_104031.1; NC_006348.1.
DR   AlphaFoldDB; Q62GY9; -.
DR   SMR; Q62GY9; -.
DR   STRING; 243160.BMA2485; -.
DR   EnsemblBacteria; AAU50164; AAU50164; BMA2485.
DR   GeneID; 56594216; -.
DR   KEGG; bma:BMA2485; -.
DR   PATRIC; fig|243160.12.peg.2563; -.
DR   eggNOG; COG1129; Bacteria.
DR   HOGENOM; CLU_000604_92_3_4; -.
DR   OMA; NVHLGHE; -.
DR   Proteomes; UP000006693; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015612; F:ABC-type L-arabinose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042882; P:L-arabinose transmembrane transport; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR017917; ABC_transptr_Ara_ATP-bd_AraG.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43790:SF6; PTHR43790:SF6; 1.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51268; ARAG; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT   CHAIN           1..503
FT                   /note="Arabinose import ATP-binding protein AraG"
FT                   /id="PRO_0000270457"
FT   DOMAIN          5..240
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT   DOMAIN          253..497
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT   BINDING         37..44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
SQ   SEQUENCE   503 AA;  55081 MW;  44559D136736052F CRC64;
     MAAALRFDNI GKVFPGVRAL DGISFDVQAG QVHGLMGENG AGKSTLLKIL GGEYQLDSGS
     VLVDGRAMRF PSAAASIAAG VAVIHQELQY VPDLTVAENL LLGRLPSALG WVRKRDAQRF
     VRERLAAMGV DLDAQAKLRR LSIAQRQMVE ICKALLRNAR VIALDEPTSS LSHRETEVLF
     KLVDDLRRDG RALIYISHRM DEIYRLCDAC TIFRDGRQVA SHASLANVPR ETLVRQMVGR
     EISDIYHYAP RALGDVRLSA RALEGDALRA GASFDVRAGE IVGFFGLVGA GRSELMRVIY
     GAQRRTGGAL MLDGEPLDIR STRDAIRRGI VLCPEDRKEE GIVAHASVAE NINISCRRHG
     LRAGLFLDRK REAETADRFI KLLKIKTPNR RQKIRFLSGG NQQKAILARW LAEPDLKVVI
     LDEPTRGIDV GAKHEIYGVI YELAKRGCAI VMVSSELPEV LGVSDRIVVM REGRIAGELA
     RGEANEEAVL NLALPQGATA HAA