ID   KLP2_BOMMO              Reviewed;         378 AA.
AC   P46874;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Kinesin-like protein KLP2;
DE   Flags: Fragment;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=C108; TISSUE=Ovary;
RX   PubMed=7704303; DOI=10.1111/j.1365-2583.1994.tb00167.x;
RA   Okano K., Takada N., Kobayashi M., Maekawa H.;
RT   "cDNA structure and characterization of a kinesin-like protein from the
RT   silkworm Bombyx mori.";
RL   Insect Mol. Biol. 3:195-200(1994).
CC   -!- FUNCTION: May be related to mitotic segregation.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Testis and ovary.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. BimC subfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00283}.
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DR   EMBL; D21206; BAA04748.1; -; mRNA.
DR   AlphaFoldDB; P46874; -.
DR   SMR; P46874; -.
DR   STRING; 7091.BGIBMGA008726-TA; -.
DR   eggNOG; KOG0243; Eukaryota.
DR   HOGENOM; CLU_001485_33_4_1; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cell cycle; Cell division; Cytoplasm; Cytoskeleton;
KW   Microtubule; Mitosis; Motor protein; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           <1..378
FT                   /note="Kinesin-like protein KLP2"
FT                   /id="PRO_0000125375"
FT   DOMAIN          13..354
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   BINDING         97..104
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   NON_TER         1
SQ   SEQUENCE   378 AA;  43036 MW;  72CD5FFE0AA4FDC5 CRC64;
     RSEKGCRKEK NQNIQVFVRL RPLNQRERDL KSLGVVEVHN NKEVVVRISQ QNSITKKFTF
     DRAFAPYANQ VEVYQEVVSP LIEEVLAGYN CTVFAYGQTG TGKTHTMVGE NTGDETTWQK
     DPLAGIIPRA LSQLFDELRI SNTEYTVRVS YLELYNEELF DLLATSEDNS KLRIYEDVTR
     KGSNIVNGLE EITVYNKKEV FRIMAQGQER KKVASTLMNA QSSRSHTVFT IVVHMKENSL
     PEGEELVKIG KLNLVDLAGS ENISKAGSDN PAKRERAREC VNINQSLLTL GRVITALVER
     HPHVPYRESK LTRILQESLG GRTKTSIIAT ISPGHKDLEE TMSTLEYLTE QRTFRTSLRS
     TRKYKESYIE RISEEIAD