ID   KLP_ARATH               Reviewed;         347 AA.
AC   F4KDD7;
DT   18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=KIN17-like protein KLP {ECO:0000305};
GN   Name=KLP {ECO:0000303|PubMed:24713636};
GN   OrderedLocusNames=At5g51795 {ECO:0000312|Araport:AT5G51795};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA   Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT   features of the regions of 1,456,315 bp covered by nineteen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:41-54(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=24713636; DOI=10.4161/psb.28634;
RA   Garcia-Molina A., Xing S., Huijser P.;
RT   "The Arabidopsis KIN17 and its homolog KLP mediate different aspects of
RT   plant growth and development.";
RL   Plant Signal. Behav. 9:E28634-E28634(2014).
CC   -!- FUNCTION: May act as repressor of root growth during copper excess and
CC       of hypocotyl growth in the dark. {ECO:0000269|PubMed:24713636}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:24713636}. Nucleus
CC       {ECO:0000269|PubMed:24713636}.
CC   -!- SIMILARITY: Belongs to the KIN17 family. {ECO:0000305}.
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DR   EMBL; AB010074; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED96127.1; -; Genomic_DNA.
DR   RefSeq; NP_680423.1; NM_148118.1.
DR   AlphaFoldDB; F4KDD7; -.
DR   SMR; F4KDD7; -.
DR   STRING; 3702.AT5G51795.1; -.
DR   PaxDb; F4KDD7; -.
DR   PRIDE; F4KDD7; -.
DR   EnsemblPlants; AT5G51795.1; AT5G51795.1; AT5G51795.
DR   GeneID; 835254; -.
DR   Gramene; AT5G51795.1; AT5G51795.1; AT5G51795.
DR   KEGG; ath:AT5G51795; -.
DR   Araport; AT5G51795; -.
DR   TAIR; locus:504954922; AT5G51795.
DR   eggNOG; KOG2837; Eukaryota.
DR   HOGENOM; CLU_030065_1_0_1; -.
DR   InParanoid; F4KDD7; -.
DR   OMA; SMFEKEF; -.
DR   OrthoDB; 1420569at2759; -.
DR   PhylomeDB; F4KDD7; -.
DR   PRO; PR:F4KDD7; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; F4KDD7; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IBA:GO_Central.
DR   CDD; cd13155; KOW_KIN17; 1.
DR   Gene3D; 1.10.10.2030; -; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   InterPro; IPR019447; DNA/RNA-bd_Kin17_WH-like_dom.
DR   InterPro; IPR037321; KIN17-like.
DR   InterPro; IPR038254; KIN17_WH-like_sf.
DR   InterPro; IPR041330; KN17_SH3.
DR   InterPro; IPR041995; KOW_KIN17.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   PANTHER; PTHR12805; PTHR12805; 2.
DR   Pfam; PF10357; Kin17_mid; 1.
DR   Pfam; PF18131; KN17_SH3; 1.
DR   SMART; SM01253; Kin17_mid; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..347
FT                   /note="KIN17-like protein KLP"
FT                   /id="PRO_0000438805"
FT   MOTIF           222..225
FT                   /note="Nuclear localization signal (NLS)"
FT                   /evidence="ECO:0000305|PubMed:24713636"
SQ   SEQUENCE   347 AA;  40102 MW;  B479A7E9D81FD6DF CRC64;
     MFVMSSSSIP NGIFIIDGQE RYVNPEGDVE SNKSERTSKA SMVFQMCEKQ CRDENGFKCH
     CMSESHQRQM QVLGQNPTRV VNGYSQEFEQ TFLDLMRRSH RFSRVAATVV YNEYINDRLH
     VHMNSTKWAT LTEFIKYLGK TAEEEKQERE IQKQIERASA GCEGKDVVVD DDDNDDDEKK
     KDEDFRLKKV GFALGLGVKE RGESSKLVFG DEENDKVERG DKRKRSALDE LMKEEEKKKE
     RMNRKDYWLF EGIIVKGVVK RVIDKYVGEI EMLESKHVLR VDQVELKTVL PQIGGMVKIV
     NGAYRGSNTR LLDLDTEKFC AKVQIEKGVY DGRVIKSIEY EDICKLA