1106L_ASFM2
ID 1106L_ASFM2 Reviewed; 118 AA.
AC P0C9H9;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 23.
DE RecName: Full=Protein MGF 110-6L;
DE Flags: Precursor;
GN OrderedLocusNames=Mal-011;
OS African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10500;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum lumen
CC {ECO:0000250|UniProtKB:P68744}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- PTM: N-glycosylated. {ECO:0000250|UniProtKB:P68744}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000000860; Genome.
DR GO; GO:0044166; C:host cell endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR InterPro; IPR004848; ASFV_fam_110.
DR Pfam; PF01639; v110; 1.
DR PROSITE; PS00014; ER_TARGET; 1.
PE 3: Inferred from homology;
KW Early protein; Host endoplasmic reticulum; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..118
FT /note="Protein MGF 110-6L"
FT /id="PRO_0000373201"
FT MOTIF 115..118
FT /note="Prevents secretion from ER"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10138"
SQ SEQUENCE 118 AA; 13791 MW; 2F0E5828D5695932 CRC64;
MLVTFLGILG LLASQVSSQL VGQLRPTEDP PEEELEYWCA YMESCQFCWD CQDGNCINKI
DGSVIYKNEY VRPCSVSRSM DKCMYDLNKG IYHSMSCSDP KAWNPYKYFR KEWKKDEL