KMCP1_MACFA
ID KMCP1_MACFA Reviewed; 291 AA.
AC Q8HXE3;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Kidney mitochondrial carrier protein 1;
DE AltName: Full=Solute carrier family 25 member 30;
GN Name=SLC25A30; Synonyms=KMCP1; ORFNames=QflA-20343;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Frontal cortex;
RA Hashimoto K., Osada N., Hida M., Kusuda J., Sugano S.;
RL Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with VDAC1. {ECO:0000250|UniProtKB:Q5SVS4}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; AB093647; BAC21621.1; -; mRNA.
DR AlphaFoldDB; Q8HXE3; -.
DR SMR; Q8HXE3; -.
DR STRING; 9541.XP_005585837.1; -.
DR eggNOG; KOG0753; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002030; Mit_uncoupling_UCP-like.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00784; MTUNCOUPLING.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Acetylation; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q5SVS4"
FT CHAIN 2..291
FT /note="Kidney mitochondrial carrier protein 1"
FT /id="PRO_0000288917"
FT TRANSMEM 9..26
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..89
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..124
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..183
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..221
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..283
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 7..96
FT /note="Solcar 1"
FT REPEAT 104..189
FT /note="Solcar 2"
FT REPEAT 198..289
FT /note="Solcar 3"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000250|UniProtKB:Q5SVS4"
SQ SEQUENCE 291 AA; 32404 MW; D87C15342ACCA5DC CRC64;
MSALNWKPFV YGGLASITAE CGTFPIDLTK TRLQIQGQTN DAKFKEIRYR GMLHALVRIG
REEGLKALYS GIAPAMLRQS SYGTIKIGTY QSLKRLFVER PEDETLLINV ICGILSGVIS
STIANPTDVL KIRMQAQSST IQGGMIGNFM NIYQQEGTRG LWKGVSLTAQ RAAIVVGVEL
PVYDITKKHL ILSGLMGDTV YTHFLSSFTC GLAGALASNP VDVVRTRMMN QRVLQDGRCS
GYTGTLDCLL QTWKNEGFFA LYKGFWPNWL RLGPWNIILF VTYEQLKKLD L
