KMCP1_XENLA
ID KMCP1_XENLA Reviewed; 291 AA.
AC Q6GQ22;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Kidney mitochondrial carrier protein 1;
DE AltName: Full=Solute carrier family 25 member 30;
GN Name=slc25a30; Synonyms=kmcp1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; BC072926; AAH72926.1; -; mRNA.
DR AlphaFoldDB; Q6GQ22; -.
DR SMR; Q6GQ22; -.
DR Proteomes; UP000186698; Genome assembly.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002030; Mit_uncoupling_UCP-like.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00784; MTUNCOUPLING.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..291
FT /note="Kidney mitochondrial carrier protein 1"
FT /id="PRO_0000288920"
FT TRANSMEM 9..26
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..89
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..124
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..183
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..283
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 7..96
FT /note="Solcar 1"
FT REPEAT 104..189
FT /note="Solcar 2"
FT REPEAT 198..289
FT /note="Solcar 3"
SQ SEQUENCE 291 AA; 32559 MW; 00529E2BAAE5AACE CRC64;
MTALNWKPFI YGGLASITAE CGTFPIDLTK TRLQVQGQPN DAKYKEIRYR GMMHAIVRIW
REEGVKALYS GIAPAMLRQA SYGTIKIGTY QSLKRLFVDC PEDETLVLNA FCGVLSGVVS
SCIANPTDVL KIRMQAQGNV MQGGMIVNFI NIYQQEGTRG LWKGVSLTAQ RAAIVVGVEL
PVYDITKKHL ILSGLMGDTV YTHFLSSFTC GLAGALASNP VDVVRTRMMN QRSIRDASNS
SYKGTLDCLL QTWKNEGFFA LYKGFWPNWL RLGPWNIIFF ITYEQLKKLN L