ID   KMCP1_XENTR             Reviewed;         291 AA.
AC   Q5XGI1; Q6P4X8;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Kidney mitochondrial carrier protein 1;
DE   AltName: Full=Solute carrier family 25 member 30;
GN   Name=slc25a30; Synonyms=kmcp1; ORFNames=TGas086a12.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH63207.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR848156; CAJ82748.1; -; mRNA.
DR   EMBL; BC084458; AAH84458.1; -; mRNA.
DR   EMBL; BC063207; AAH63207.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001165746.1; NM_001172275.1.
DR   RefSeq; XP_012812119.1; XM_012956665.2.
DR   AlphaFoldDB; Q5XGI1; -.
DR   SMR; Q5XGI1; -.
DR   STRING; 8364.ENSXETP00000014720; -.
DR   PaxDb; Q5XGI1; -.
DR   Ensembl; ENSXETT00000066458; ENSXETP00000060775; ENSXETG00000014651.
DR   GeneID; 394840; -.
DR   KEGG; xtr:394840; -.
DR   CTD; 253512; -.
DR   Xenbase; XB-GENE-995074; slc25a30.
DR   eggNOG; KOG0753; Eukaryota.
DR   HOGENOM; CLU_015166_14_2_1; -.
DR   InParanoid; Q5XGI1; -.
DR   OrthoDB; 1126848at2759; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000014651; Expressed in heart and 17 other tissues.
DR   ExpressionAtlas; Q5XGI1; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR   GO; GO:0015140; F:malate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015131; F:oxaloacetate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015117; F:thiosulfate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0071423; P:malate transmembrane transport; IBA:GO_Central.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0015729; P:oxaloacetate transport; IBA:GO_Central.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0071422; P:succinate transmembrane transport; IBA:GO_Central.
DR   GO; GO:0008272; P:sulfate transport; IBA:GO_Central.
DR   GO; GO:0015709; P:thiosulfate transport; IBA:GO_Central.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR002030; Mit_uncoupling_UCP-like.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00784; MTUNCOUPLING.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..291
FT                   /note="Kidney mitochondrial carrier protein 1"
FT                   /id="PRO_0000288921"
FT   TRANSMEM        9..26
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..89
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..124
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..183
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..283
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          7..96
FT                   /note="Solcar 1"
FT   REPEAT          104..189
FT                   /note="Solcar 2"
FT   REPEAT          198..289
FT                   /note="Solcar 3"
SQ   SEQUENCE   291 AA;  32453 MW;  A9C9979265FA731F CRC64;
     MTALNWKPFI YGGLASITAE CGTFPIDLTK TRLQVQGQAN DAKYKEIRYR GMLHAIVRIW
     KEEGVKALYS GIAPAMLRQA SYGTIKIGTY QSLKRLFVDC PEDETLVINV FCGVLSGVVS
     SCIANPTDVL KIRMQAQGSL IQGGMIGNFI NIYQQEGTRG LWKGVSLTAQ RAAIVVGVEL
     PVYDITKKHL ILSGLMGDTV YTHFLASFTC GLAGALASNP VDVVRTRMMN QRSIRNVSNS
     SYKGTLDCLL QTWKNEGFFA LYKGFWPNWL RLGPWNIIFF ITYEQLKKLN L