ARAG_PARXL
ID ARAG_PARXL Reviewed; 516 AA.
AC Q13U53;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Arabinose import ATP-binding protein AraG {ECO:0000255|HAMAP-Rule:MF_01721};
DE EC=7.5.2.12 {ECO:0000255|HAMAP-Rule:MF_01721};
GN Name=araG {ECO:0000255|HAMAP-Rule:MF_01721}; OrderedLocusNames=Bxeno_A3848;
GN ORFNames=Bxe_A0547;
OS Paraburkholderia xenovorans (strain LB400).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=266265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LB400;
RX PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT shaped for versatility.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC -!- FUNCTION: Part of the ABC transporter complex AraFGH involved in
CC arabinose import. Responsible for energy coupling to the transport
CC system. {ECO:0000255|HAMAP-Rule:MF_01721}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + L-arabinose(out) = ADP + H(+) + L-arabinose(in) +
CC phosphate; Xref=Rhea:RHEA:30007, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17535, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.12;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01721};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (AraG),
CC two transmembrane proteins (AraH) and a solute-binding protein (AraF).
CC {ECO:0000255|HAMAP-Rule:MF_01721}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01721}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01721}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Arabinose
CC importer (TC 3.A.1.2.2) family. {ECO:0000255|HAMAP-Rule:MF_01721}.
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DR EMBL; CP000270; ABE32386.1; -; Genomic_DNA.
DR RefSeq; WP_011489864.1; NZ_CP008760.1.
DR AlphaFoldDB; Q13U53; -.
DR SMR; Q13U53; -.
DR STRING; 266265.Bxe_A0547; -.
DR EnsemblBacteria; ABE32386; ABE32386; Bxe_A0547.
DR KEGG; bxb:DR64_2722; -.
DR KEGG; bxe:Bxe_A0547; -.
DR PATRIC; fig|266265.5.peg.4067; -.
DR eggNOG; COG1129; Bacteria.
DR OMA; NVHLGHE; -.
DR OrthoDB; 551294at2; -.
DR Proteomes; UP000001817; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015612; F:ABC-type L-arabinose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042882; P:L-arabinose transmembrane transport; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017917; ABC_transptr_Ara_ATP-bd_AraG.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43790:SF6; PTHR43790:SF6; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51268; ARAG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW Translocase; Transport.
FT CHAIN 1..516
FT /note="Arabinose import ATP-binding protein AraG"
FT /id="PRO_0000270464"
FT DOMAIN 5..240
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT DOMAIN 240..497
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
SQ SEQUENCE 516 AA; 56634 MW; 0D28B191F00585D0 CRC64;
MSATLRFDNI GKVFPGVRAL DGVSFDVNVG QVHGLMGENG AGKSTLLKIL GGEYQPDSGR
VMIDGNEVRF TSAASSIAAG IAVIHQELQY VPDLTVAENL LLGQLPNSLG WVNKREAKRF
VRERLEAMGV ALDPNAKLRK LSIAQRQMVE ICKALLRNAR VIALDEPTSS LSHRETEVLF
KLVRDLRADN RAMIYISHRM DEIYELCDAC TIFRDGRKIA SHPTLEGVSR DTIVSEMVGR
EISDIYNYSA RPLGEVRFAA KAIEGHALAQ PASFEVRRGE IVGFFGLVGA GRSELMHLVY
GADRKKGGEL TLDGKPIKVR SAGEAIRHGI VLCPEDRKEE GIVAMASVSE NINISCRRHY
LRAGMFLDRK KEAETADRFI KLLKIKTPSR RQKIRFLSGG NQQKAILSRW LAEPDLKVVI
LDEPTRGIDV GAKHEIYNVI YQLAERGCAI VMISSELPEV LGVSDRIVVM RQGRISGELA
RQDATEQSVL SLALPQSSTA LPGTDAGTET AAQQAA