ARAG_RALSO
ID ARAG_RALSO Reviewed; 511 AA.
AC Q8XVS2;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Arabinose import ATP-binding protein AraG {ECO:0000255|HAMAP-Rule:MF_01721};
DE EC=7.5.2.12 {ECO:0000255|HAMAP-Rule:MF_01721};
GN Name=araG {ECO:0000255|HAMAP-Rule:MF_01721}; OrderedLocusNames=RSc2757;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- FUNCTION: Part of the ABC transporter complex AraFGH involved in
CC arabinose import. Responsible for energy coupling to the transport
CC system. {ECO:0000255|HAMAP-Rule:MF_01721}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + L-arabinose(out) = ADP + H(+) + L-arabinose(in) +
CC phosphate; Xref=Rhea:RHEA:30007, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17535, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.12;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01721};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (AraG),
CC two transmembrane proteins (AraH) and a solute-binding protein (AraF).
CC {ECO:0000255|HAMAP-Rule:MF_01721}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01721}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01721}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Arabinose
CC importer (TC 3.A.1.2.2) family. {ECO:0000255|HAMAP-Rule:MF_01721}.
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DR EMBL; AL646052; CAD16464.1; -; Genomic_DNA.
DR RefSeq; WP_011002664.1; NC_003295.1.
DR AlphaFoldDB; Q8XVS2; -.
DR SMR; Q8XVS2; -.
DR STRING; 267608.RSc2757; -.
DR EnsemblBacteria; CAD16464; CAD16464; RSc2757.
DR GeneID; 60502259; -.
DR KEGG; rso:RSc2757; -.
DR eggNOG; COG1129; Bacteria.
DR HOGENOM; CLU_000604_92_3_4; -.
DR OMA; NVHLGHE; -.
DR Proteomes; UP000001436; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015612; F:ABC-type L-arabinose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042882; P:L-arabinose transmembrane transport; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017917; ABC_transptr_Ara_ATP-bd_AraG.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43790:SF6; PTHR43790:SF6; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51268; ARAG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW Translocase; Transport.
FT CHAIN 1..511
FT /note="Arabinose import ATP-binding protein AraG"
FT /id="PRO_0000270474"
FT DOMAIN 5..240
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT DOMAIN 240..501
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01721"
SQ SEQUENCE 511 AA; 55936 MW; 8A865728F8FADC1C CRC64;
MSAFLEFRGI SKVFPGVRAL SEVSFGIECG RVHGLLGENG AGKSTLLKIL GGDYQPDGGQ
IAVEGRPVAF PNARAALAAG IAVIHQELQT VPELTVMDNL LLGHLPSRGG FIRQGEAMAW
TRAQLARIGV DLDPKARLKH LSIGQRQMVE ICKAILRDAR VIALDEPTSS LSVRETDILF
RLVKDLRAQG RALIYISHRL DEIFALCDGC TIFRDGRKVA DFRSMADVTR EQLVAQMVGR
QIDDIFGYRP RAPGDVRLRV EGLMGPKLAE PASFAVRRGE IVGLFGLVGA GRSELARLVY
GADRKTAGTV VLDGEPIRIR AVADAIRQGI VLCPEDRKEE GIIGCRSVSE NINISCRRNR
RPGWGGFNLF VDDRQEAKTA DHYIARLRIK TPHRDQPIRL LSGGNQQKAI LARWLAEDGM
RVLIIDEPTR GIDVGAKNEI YQVLYELAER GVAVLMISSE LPEILGVADR VLVMSEGRIA
GELPRAQATE HAVLNLALRP RRDPCVAAQA A