KN12B_ORYSJ
ID KN12B_ORYSJ Reviewed; 1114 AA.
AC Q6K765; A0A0P0VJ40; B9F023; C7IYS1;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 07-SEP-2016, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Kinesin-like protein KIN-12B {ECO:0000305};
DE Short=OsKinesin-12B {ECO:0000303|PubMed:19106179};
GN Name=KIN12B {ECO:0000305};
GN OrderedLocusNames=Os02g0489800 {ECO:0000312|EMBL:BAS78735.1},
GN LOC_Os02g28850 {ECO:0000305};
GN ORFNames=OsJ_06785 {ECO:0000312|EMBL:EEE57014.1},
GN OSJNBa0048K16.12 {ECO:0000312|EMBL:BAD21882.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19106179; DOI=10.1093/aob/mcn248;
RA Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT monocots by mining the rice genome.";
RL Ann. Bot. 103:387-402(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-12 subfamily.
CC {ECO:0000303|PubMed:19106179}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD21882.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAH91696.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAS78735.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EEE57014.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP004864; BAD21882.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAH91696.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; BAS78735.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000139; EEE57014.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015623659.1; XM_015768173.1.
DR AlphaFoldDB; Q6K765; -.
DR SMR; Q6K765; -.
DR STRING; 4530.OS02T0489800-00; -.
DR PRIDE; Q6K765; -.
DR GeneID; 9270703; -.
DR KEGG; osa:9270703; -.
DR eggNOG; KOG4280; Eukaryota.
DR HOGENOM; CLU_009194_1_0_1; -.
DR InParanoid; Q6K765; -.
DR OrthoDB; 130600at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; PTHR24115; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..1114
FT /note="Kinesin-like protein KIN-12B"
FT /id="PRO_0000437195"
FT DOMAIN 117..459
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 772..810
FT /evidence="ECO:0000255"
FT COILED 999..1043
FT /evidence="ECO:0000255"
FT COMPBIAS 65..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 197..204
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1114 AA; 123912 MW; BEF292AB2E0ACBFE CRC64;
MRSLFSSKLS RAPASPPPPP PHAAAGGGGD AHTPSSHGHR HRRFPKENVD PSPSPGPYDH
HSAYRSPSGK QQQQQPLAAK NRSLPPRPPL KRKLLDVSAA SPAPEGAPSG GGGGDSGVQV
VVRVRPPSRA EEEDEGAGKE VCVRKTGPGS VEIHGQGFTF DSVADEASTQ EDIFQLVGRP
LVENCLDGFN SSIFAYGQTG SGKTYTMWGP LSALSDDTVS KERGLTPRVF ELLFSRIKEE
QAKHSNKQLV YHCCCSFLEI YNEQITDLLD PVQRNLQIRE DVGTSSVYVE SLTKESVFTI
NDVTQLLEKG LANRRTEATT ANAESSRSHC VFTCFIKSES KNMEDGSNFT RTSRINLVDL
AGSERQKLTN AAGDRLKEAG NINRSLSQLG NLINILAEVS QSGKQRHHIP YRDSKLTFLL
QESLGGNAKL AMICAVSPSQ NCKSETLSTL RFAHRAKDIK NNAVVNEQRE DDVNVLREQI
RQLKEELQHV RSNGSLPGSN GSPSTGWNSQ NSFLLKMSLS RPTAFPTIKD DSDEEMEIDD
NDVEKPCNLE NKSSFPHGDV ETSRCKSNLA ASIQKGLQVI ESHRNSVTWR RSSLGLNTRL
MDAHLSVPVC KVDVAIQTDP EESEPRQNTM ALIPSNQPEA TTDGNREISD CINLQLVTVD
GSIPSNDLKQ QEQVFKAVEK VLAGAIRREM LRDEQCAKQA AEIQQLKRLV QQYKHERECN
AAIAQIREEK IARLETLVDG ILPTEELMHA ENLSLQDENK ILHQKYENHP EVLSAKIELE
RIQEELERYR NFKDEKEVLL EEIQHLKNQL HYMLSSSMAL CRPPVELVQA ISTVSDRPTI
SALEEAGDDG HSIVDAAESR WITLTEELRV ELEKSKSLSE RLQLEVESEK QCSEELKGAL
EMAMQGHARI LEQYCELQEK HASLLSMCRT INDGIEDVKK EAAKAGVRGA ESKFINALAR
QVSILRAERE KERRFWMDEN KGLQQQLSDT AEAVQAAGEL LVRLNDAEEA ASLAQKRAEL
AEQEMNKAFA EIDNLKRDHD QEVLVLNQRL AESKLPSNVV QSPEPSETGP ARYDTGGSFG
DEQWREEFKP FQSVEVSKSS DPSSWFYGYD KCNI
