KN12C_ORYSJ
ID KN12C_ORYSJ Reviewed; 1129 AA.
AC Q5W6L9; B9F9H5; Q6F2U4;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Kinesin-like protein KIN-12C {ECO:0000305};
GN Name=KIN12C {ECO:0000305};
GN OrderedLocusNames=Os03g0587200 {ECO:0000312|EMBL:BAS85105.1},
GN LOC_Os03g39020 {ECO:0000312|EMBL:ABF97362.1};
GN ORFNames=OsJ_11583 {ECO:0000312|EMBL:EEE59423.1},
GN OSJNBa0010D22.30 {ECO:0000312|EMBL:AAT76328.1},
GN OSJNBb0085A04.1 {ECO:0000312|EMBL:AAV35794.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19106179; DOI=10.1093/aob/mcn248;
RA Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT monocots by mining the rice genome.";
RL Ann. Bot. 103:387-402(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-12 subfamily.
CC {ECO:0000303|PubMed:19106179}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK121995; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=EEE59423.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC133003; AAT76328.1; -; Genomic_DNA.
DR EMBL; AC135502; AAV35794.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF97362.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF12490.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS85105.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE59423.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK121995; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015631781.1; XM_015776295.1.
DR AlphaFoldDB; Q5W6L9; -.
DR SMR; Q5W6L9; -.
DR STRING; 4530.OS03T0587200-01; -.
DR PaxDb; Q5W6L9; -.
DR PRIDE; Q5W6L9; -.
DR EnsemblPlants; Os03t0587200-01; Os03t0587200-01; Os03g0587200.
DR GeneID; 4333349; -.
DR Gramene; Os03t0587200-01; Os03t0587200-01; Os03g0587200.
DR KEGG; osa:4333349; -.
DR eggNOG; KOG4280; Eukaryota.
DR HOGENOM; CLU_009194_0_0_1; -.
DR InParanoid; Q5W6L9; -.
DR OMA; IVESWCK; -.
DR OrthoDB; 130600at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; PTHR24115; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..1129
FT /note="Kinesin-like protein KIN-12C"
FT /id="PRO_0000437196"
FT DOMAIN 97..434
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 623..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 994..1083
FT /evidence="ECO:0000255"
FT COMPBIAS 51..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1105..1119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 174..181
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT CONFLICT 18
FT /note="Missing (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 206
FT /note="R -> H (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 279
FT /note="D -> G (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 299
FT /note="N -> S (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 464
FT /note="R -> Q (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 568
FT /note="D -> G (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
FT CONFLICT 740
FT /note="D -> G (in Ref. 6; AK121995)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1129 AA; 124697 MW; 4E42D95F8F54D3C4 CRC64;
MEMLRRNLKR QASRSLSAFA VSSPRAGAVA AADADQENLH PNLAAASPPM SPAAKNSSAA
PGASPRSSKP VPTSAAPPSK AAAEGEQASA PANEAPAVKV VVRVRPTVSR PVDGKDLFFV
RKTSPCSVAV GDRSFAVDGF LDDRASQADA FDLIGVPMIE SALAGFNSSL VCYGQSGTGK
TYTMFGALAA MVDSSSDHAD RGVVPRVFQN LFAQIQGRQE SSPEKQTSYQ CRCSFLEVHN
EQINDLLDPS QRNLQIRENA GNGIHVENLT DEYVSTVEDV NQILMKGLSN RKVGTTSMNL
KSSRSHVIFS CVIEAWSKGF SNGFSSSRTS RITFVDLAGP DNDELDGGNK HCTREERYVK
KSLSKLGKLV NILSEAPETQ KDDSPHKQSC LTHVLKDTLG GNSRVTFLCS ISSEHRCRTT
TLSTLRFGER AKLMSNKAVV NEISEDDVNG LSDQIRQLKD ELIRTKSGDT EPCKNGYFSA
QNARESLHNL RVSLNRSLIL PHIEVDSEEE MDVDEEDVQE LRDQIRKLHS SSEDTFDDFM
DAESGDDTPC SKGNPKTSEE DDQPVIDDCE DPIQEEHEVL SSTKVDQDLV SDRKSFLSVS
ASPHLSPMQD PTLCSSPKIH NKARKSITSP GLSPSKLSVS DCPGDEVSRK SAVRSSLQSS
KLSPTDSLAA SLQRGLHIME YHEQNQGPRK SFVGLSFDHF ALNPRQSVAK VSSGVLASPE
RKGATSSALC SSCKKAIDTD GNQKDNINAE KQIVIATSVV PEVKDDITAS TIASKRQTEL
EALCEEQADK IKELSNLVDQ YKKCSEDAQN SDGTEPTKEL VDEAKVGEQH GELNVNDREE
LLSEIQRLKD QLKQQAGEST NVSLLEHLRN GSTDQEYELD REREKWMESE SKWICLTEEL
RVDLESNRML AEKTEMELSN EKKCTAELDD ALQRAIYGHA RIIEHYAELQ EMYNDLLERH
RRVMEGISEV KRAAAKAGRK GCGTAFAAAL AAELSTVRID REKERAQLKE QNRRLRIQLR
DTAEAVHAAG ELLVRLREAE EASTQEKERS AAMQQENDKL KKQLEKMKKK HEMEMETMKH
FLADSRLPES ALGGFYRQES EDVPEYNNHA TSTCDDDQSW RAAFTSAYE
