ID   KN12E_ORYSJ             Reviewed;        1892 AA.
AC   B9FUF9; A0A0P0X9F0; Q0D4A4; Q69R12;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 2.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Kinesin-like protein KIN-12E {ECO:0000305};
GN   Name=KIN12E {ECO:0000305};
GN   OrderedLocusNames=Os07g0638000 {ECO:0000312|EMBL:BAT02836.1},
GN   LOC_Os07g44400 {ECO:0000305};
GN   ORFNames=OJ1340_C08.103 {ECO:0000312|EMBL:BAD31261.1},
GN   OsJ_25289 {ECO:0000312|EMBL:EEE67666.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1492-1892.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19106179; DOI=10.1093/aob/mcn248;
RA   Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT   "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT   monocots by mining the rice genome.";
RL   Ann. Bot. 103:387-402(2009).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-12 subfamily.
CC       {ECO:0000303|PubMed:19106179}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD31261.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF22319.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAG87394.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAT02836.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EEE67666.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP005292; BAD31261.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008213; BAF22319.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014963; BAT02836.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CM000144; EEE67666.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AK060298; BAG87394.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; B9FUF9; -.
DR   SMR; B9FUF9; -.
DR   STRING; 4530.OS07T0638000-01; -.
DR   PRIDE; B9FUF9; -.
DR   eggNOG; ENOG502QR1R; Eukaryota.
DR   HOGENOM; CLU_024288_0_0_1; -.
DR   Proteomes; UP000000763; Chromosome 7.
DR   Proteomes; UP000007752; Chromosome 7.
DR   Proteomes; UP000059680; Chromosome 7.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..1892
FT                   /note="Kinesin-like protein KIN-12E"
FT                   /id="PRO_0000437197"
FT   DOMAIN          64..401
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1633..1656
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1870..1892
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          406..438
FT                   /evidence="ECO:0000255"
FT   COILED          486..526
FT                   /evidence="ECO:0000255"
FT   COILED          1066..1139
FT                   /evidence="ECO:0000255"
FT   COILED          1303..1357
FT                   /evidence="ECO:0000255"
FT   COILED          1396..1528
FT                   /evidence="ECO:0000255"
FT   COILED          1780..1841
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1633..1649
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         145..152
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1892 AA;  214446 MW;  33062625AD6323A3 CRC64;
     MAGHGAGGRR ASTSRAAARR VEAETNENDD LAAAAARDLA AAEVPAEVPH FELDEDPAFW
     KDRNVQVLIR IRPINAAEST ANGQRRCLVQ DSSKTLSWTG HPDTMFTFDH VACETISQEK
     LFGVVGLPMV ENCMSGYNGC LFAYGQTGSG KTYTMMGELS KLDNELSKDS GLTPRIFEYL
     FARIKEEEER RREDKLKYIC KCSFLEIYNE QITDLLEPSS TNLQIREDIK KGVYVENLME
     CYVSSVKDVM MLLLQGVANR KMAATNMNSE SSRSHSVFTC VIESRWERDS MTHLRFGRLN
     LVDLAGSERQ KSSGAEGERL KEAANINRSL STLGLVIMTL VDVANGKNRH VPYRDSRLTF
     LLQDSLGGNS KTTIVANVSP SICSSSETLS TLKFAQRAKL IQNNAKVNED ASGDVMSLQR
     QIEDLKDQLT CLKKQQNMPG SPSFKLLKSG YGNEFNSLHG VDDQSACDLE LLKQKVIHLE
     DVLVGSLRRE KSAETEIRKL ECEIKSLNRL VNLMESDTRH LRTTVKLRDE KIRRLELLAD
     NQISSDGYLM DENAAMFQEI QLLQEQINDN SQLTQFALEN KRLIEQVRML EKFSKQGERE
     MLLTEISLLR NHFLHILEQK YARPPKNMEA QGDVTIKELE TCRKELDACL ENNVLLAREV
     NKLRCELKQY QKCGTGQVAP EVVESSVIPG INQKQHDQAG WCGSYLASID VERQFVDVGI
     TTDITESLEL TPPSEIYSEN QDSPSRLHFS DPEICDLKNS TKVLEYNSSR NLLDKGIILS
     GQLENECGLN SVQNDEISLV KENAEKMYGH DEISVYRQNE ILHSSEQLLQ DELTHIKSLN
     EGLKEKLIIM AEESTKLSEI IVAKDVEIAT LSEEWESAIV DLTSFLTDGC SSLDDAYQNI
     DNMISSFPYN NHSVSEHVEK AMKVSIEKEK IISRLQIELQ AAQRMGREVK EKLHILRGAT
     LAITEAQLLD NDESQEALKL LDLMRQKDCT VQELNDNVKQ KSCLFAEATE GYSRHECHLP
     DNVGTVAEIS HNRDGSEVNQ ANTHYQAKLE DVLHLVEDKS NKVLALFSNF EEAQETMEEA
     ETMLSSLLKA NEELKLEKDS CRQAVELLFA ERTSLINDLQ ELEASNSFTA QRYDKLHEQV
     NGCVAEMTNL ATIIKESFHQ VQRVTTVELF AFCSEVISFG QDLRKWIYES RSYLVNMGAL
     LEEQGNSYAE QNRRTNSSTY AGVSQQVESC SRQLGGMNGD IFPGTYMVVD GKEKASVHVV
     PFGSNAELED TNVERTFDMD YASLRREFDR KSDVAEGLSF DLKLLQESTS QAKDMKDKAD
     EISDALVSVQ RELEKKTSAM ESILKQQKVL EEELAENGAA LLILRSELEH SESLSSELFK
     ENNNLKVMLE EEAMMISETK AMLEDKSKVI EGLEHEILLL NSSEEGRLMS QIKELNDNLK
     IISIDKGNLE EEILKLTDKL EMAVALAEEN EAASIEARQA AEISKVYAEE KEEEVRILER
     SVEELESTIT VLEEEVCNLK EEVRSYQIYK KSEAEQAQEM FIVDSTSKCD ATEQLCPGRC
     QLEKRLKAEI IAHQDARRKI ECLTMEASCK DEEVRQYKEH IAELVLHSEA QSLLFQEKYQ
     EMEHMISKQK FGLHESNSDT GHTKFEKPSG RTRGSGSPFR CISSIVQQMN SEKDQEISVA
     RQRIEELEGL VCNKQKEICM LTSRLAAVDS MTHDIIRELL GVKLDMTNYA NMLDQEELQK
     LLMASQQQIE QSKAKDVELD MLKEQFDHLI QERDSLFDDM DQRKADLLES QLLIEQLEQR
     EQMLEAQNGI LQMEKDNLQQ RIMEMDEEIQ LLVGSNQAIA ETTFQMGSNH RSANSEFSRR
     LAQSDMLLSH ARHEHSRLQA AKSSRTRRGS HQ