ID   KN12F_ORYSJ             Reviewed;        2798 AA.
AC   B9GE13; A0A0P0YBR9; Q0IM79; Q2QMU6;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Kinesin-like protein KIN-12F {ECO:0000305};
GN   Name=KIN12F {ECO:0000305};
GN   OrderedLocusNames=Os12g0590500 {ECO:0000312|EMBL:BAT17878.1},
GN   LOC_Os12g39980 {ECO:0000312|EMBL:ABA99145.1};
GN   ORFNames=OsJ_36705 {ECO:0000312|EMBL:EEE53520.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19106179; DOI=10.1093/aob/mcn248;
RA   Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT   "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT   monocots by mining the rice genome.";
RL   Ann. Bot. 103:387-402(2009).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-12 subfamily.
CC       {ECO:0000303|PubMed:19106179}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA99145.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF30186.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAT17878.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DP000011; ABA99145.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008218; BAF30186.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014968; BAT17878.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CM000149; EEE53520.1; -; Genomic_DNA.
DR   SMR; B9GE13; -.
DR   STRING; 4530.OS12T0590500-00; -.
DR   PRIDE; B9GE13; -.
DR   eggNOG; ENOG502QR1R; Eukaryota.
DR   HOGENOM; CLU_000399_0_0_1; -.
DR   Proteomes; UP000000763; Chromosome 12.
DR   Proteomes; UP000007752; Chromosome 12.
DR   Proteomes; UP000059680; Chromosome 12.
DR   GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR   GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..2798
FT                   /note="Kinesin-like protein KIN-12F"
FT                   /id="PRO_5004214227"
FT   DOMAIN          210..547
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          1..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          600..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2338..2359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2772..2798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          792..835
FT                   /evidence="ECO:0000255"
FT   COILED          890..987
FT                   /evidence="ECO:0000255"
FT   COILED          1014..1108
FT                   /evidence="ECO:0000255"
FT   COILED          1281..1322
FT                   /evidence="ECO:0000255"
FT   COILED          2130..2333
FT                   /evidence="ECO:0000255"
FT   COILED          2361..2427
FT                   /evidence="ECO:0000255"
FT   COILED          2545..2758
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        12..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..160
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2338..2352
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         291..298
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   2798 AA;  317312 MW;  91F019EB45DDDC12 CRC64;
     MVRDLAAVRR TPARASTSSS ASEVGNDENA PVDASDAAVV EPEAAAARPP LLAIQPPQSG
     LKRKPESPAP TPSKLPFRTP EKAAARSRFG WVPPRGEEQP PPRVGGTPYS AVSTPGRHRG
     KSSAAAASEG GGGSTQSTPT KSVTKPAYSI GMSASRPPMS SGQRGAGLGL GFSMAARGTP
     MSFAPVTVVN TAEVPHFELR EDPSFWMENN VQVVIRVRPL NNTERNLHNY NRCLKQESAQ
     SITWIGQPES RFTFDHVACE AVNQEVLFRV AGLPMVENCM AGYNSCIFAY GQTGSGKTYT
     MLGEISELEV RPSQDRGMTP RIFEFLFARI RAEEESRRDE KLKYNCKCSF LEIYNEQITD
     LLDPSSTNLP LREDIRNGVY VENLTELEVG CVSDIIKLLM QGSANRKVAA TNMNRESSRS
     HSVFTCIIES RWEKDSASNL RFARLNLVDL AGSERQRTSG AAGERLKEAA NINKSLSTLG
     LVIMSLVDQA HGKQRHVPYR DSRLTFLLQD SLGGNSKTMI IANVSPSVCS ASETLSTLKF
     AQRARLIQNN AVVNEDASGD VLALQHQIRL LKEELAVLKR QRVPRSLSFT SDIFERSGVD
     VDDGTESMNM DEENDNDAHD RRSLQDLRIS NKQLRLLEET LAGAFRRESV AEATVKQLEA
     EIEQLNRMVY ERENDTRSAK MTLKFREDKI HQMEALVRDK LPAESYLLEE NNTLLKEIDL
     LRAKIDKNPE VTRFALENIR LSNKLKSYNQ FCNEGEREHL LNEVSILRNQ VLQILERRAE
     AEQPNNFPTN FELKRTSQEL ETCRGELQAC LEANKKLARE IADLQNELSN IHSSNREGHP
     NVVEKFSSAL NQYDSHAPEK KDQCFQEGFM INTDDILNLQ LELDIIKTIL AEERTTRAEV
     EKRITCLDDE LKAANIHILQ TCRQSETMQR ELSDARSVIE ALESQQIMLI NELDELKESN
     QQSLEHLKKR DLEISRLNNE LDVHRRQEFL AMEEPKVQLL KCFENDDSPL QTKLKRMQAS
     LEKARKLNTR YQRDQASHSS AQQEMDEVSR QVEVETAEVI MCLQEELISL QQQLDASSKN
     ELLANQRIDE ARLEREQLND RLLEVMKENE CFSALIEEKD KKIGMLTNDW DKLASDIGNF
     LLDGNAALDE ASDQVAFISE SISQRKWIED QVQKMCRGIS QRDELLKELQ SRLKEADDIR
     CDLDLKLRSL RGAMQAINDT HQQEKNDQEN AMSVLRSQES NERYVNQQQL QELQRIQLLL
     DESIESFVQK EVIEQSYISL QRAMEEVIHH LESQLDQSKR DLTQLLSETQ DKEQAFERLK
     NEENGVLLTV LSDVLKAKGV IHEFETGFNA IQSSFSVDPE EVVCQNSDLN LEDRVGCDPT
     GAFEAGEKHN GDVLCKLSKE MECVVYTMQM LQSQMVKLLQ EKENAKEYHF QSQRTIKDVS
     AKVLQLKSEI IDKEKGYEAR LKELEIKMQE KEKDTAESFI SWNKEREALE LEVSEAKSLA
     IQKSFEASTL ISKFEEAQAT ISDADTTVNA LVEANEKAKL QIQNFKENEA LFLSEKERLL
     TEISSLKMLL DVKDQTYEVM EKKFAASLLE ANDLALELED GIRHLQNLLL EKLEFVSSDV
     EWMKSKLQQF AELARTWLEE NWLEIIGKDC AVSVLHLCHM GILLERITGL NAENGFLQRG
     LCESNSLISK LREHNDRAKN ELEMCSVLKG KLLLDINHNF SRIAKKEQEA TELNSRLDAF
     EKKILHLQAQ EEAMLARSNS MYNELSILVE EIDATNKSAL ATESKEKEEL RHQLDEALLC
     NAMLKDIIQE DVDLPQVNNY MKGCSEFELC NRLADYHNEL VTTNIIAKDI ESFVLSSELV
     QQKAQLQKQE LMFIDALDGL TTEATLSRVD KDLGSAVIFS LLDDSNKIMI DFDNLKQNKD
     ELMENLHVLS EENLNLRSVV GSLESSIESL QTELDGKTKA LMELQYSHTT ILEEFKLKSK
     ATELGVSREN DLRSENNLLK HEYLDIVRKE QMMAELVANL DSEKLFVTIQ GRLEQVADQV
     QMYTSDQLNM VTKVSNEIDF IQMSIEGLIT HNGFLQSELI RKDELAKGLS FDLSLLQESA
     SVAKDQADEL IQLTEAIESL EPELDSKSNE LVDAVSGRQL LEAQILKSNQ KVSALEEQLA
     SKINELKEVS VEKDELTSKL NHIEGISYTM EDELADKSKA IERLEEELIE LRSLLDARTC
     FLQNLQNDFS KLLDEKKYCE TQVLILNEKL EMAQALAEES EAIATEAKQM AEERKTHAEE
     KDEEVKLLER SIEELETTVC ALENKVDIIK EEAERQRMHR EEIELELQKV RQQMLAVPSS
     GQATSSLEGG MGDFTDSSRH SREIKNELLA AQENIRILQK DVAEKETEIA QCKAHISELN
     IHAEAAAREY KQKFMELEAM AQQVKSDNTS ANACSTRPEK ISLKPRGSGS PFKCIGLGFV
     QQMNSEKDEE LSAAKQRIME LEGIAASRQR EIFMLNARLA TTESMTHDVI RDMLGVKMNM
     ATWAALVDNQ QQMDTQESAV TQAHESKEQS DELMKLRSQL DELIEERQSW LDEINQRQSE
     LGAARITIEK LRQKEHFMVA EIELLKAENA NGKAIIFNLE DEVKKLTRQQ NLQLRINHHE
     ENNLLKKQNE ELSAKLQKLG AVVARTKEEL ARYRVSDGKD PYEQMEEEEL LRNRLEESEQ
     DRSKLAENLS SLCATVLKIA GVRNHESDAS LLKALEALNQ IQLRIASMEA GVEDLKLKCK
     LLHEKARLSE LRSESSSLSS GRSRSPSVCR SPSISSFR