ID   KN14H_ORYSJ             Reviewed;         788 AA.
AC   Q0J9V3; A0A0P0WF75; Q7XN65;
DT   18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Kinesin-like protein KIN-14H {ECO:0000305};
GN   Name=KIN14H {ECO:0000305};
GN   OrderedLocusNames=Os04g0629700 {ECO:0000312|EMBL:BAS91157.1},
GN   LOC_Os04g53760 {ECO:0000305};
GN   ORFNames=OsJ_16274 {ECO:0000312|EMBL:EEE61745.1},
GN   OSJNBa0089N06.17 {ECO:0000312|EMBL:CAE04256.3};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19106179; DOI=10.1093/aob/mcn248;
RA   Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT   "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT   monocots by mining the rice genome.";
RL   Ann. Bot. 103:387-402(2009).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q0J9V3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q0J9V3-2; Sequence=VSP_058691;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-14 subfamily.
CC       {ECO:0000303|PubMed:19106179}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAE04256.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL662988; CAE04256.3; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008210; BAF15884.1; -; Genomic_DNA.
DR   EMBL; AP014960; BAS91157.1; -; Genomic_DNA.
DR   EMBL; AP014960; BAS91158.1; -; Genomic_DNA.
DR   EMBL; CM000141; EEE61745.1; -; Genomic_DNA.
DR   EMBL; AK064973; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK122184; BAH00835.1; -; mRNA.
DR   RefSeq; XP_015635978.1; XM_015780492.1. [Q0J9V3-2]
DR   RefSeq; XP_015635979.1; XM_015780493.1. [Q0J9V3-1]
DR   AlphaFoldDB; Q0J9V3; -.
DR   SMR; Q0J9V3; -.
DR   STRING; 4530.OS04T0629700-02; -.
DR   PRIDE; Q0J9V3; -.
DR   EnsemblPlants; Os04t0629700-01; Os04t0629700-01; Os04g0629700. [Q0J9V3-1]
DR   GeneID; 4337093; -.
DR   Gramene; Os04t0629700-01; Os04t0629700-01; Os04g0629700. [Q0J9V3-1]
DR   KEGG; osa:4337093; -.
DR   eggNOG; KOG0239; Eukaryota.
DR   HOGENOM; CLU_001485_12_2_1; -.
DR   InParanoid; Q0J9V3; -.
DR   OrthoDB; 364605at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000007752; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   ExpressionAtlas; Q0J9V3; baseline and differential.
DR   GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR   GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR   GO; GO:0051225; P:spindle assembly; IBA:GO_Central.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; ATP-binding; Coiled coil; Microtubule; Motor protein;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..788
FT                   /note="Kinesin-like protein KIN-14H"
FT                   /id="PRO_0000438634"
FT   DOMAIN          432..767
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..430
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        37..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         518..525
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   VAR_SEQ         353
FT                   /note="E -> EVSGFRLTKSILSVRNYLAHHYASAQ (in isoform 2)"
FT                   /id="VSP_058691"
FT   CONFLICT        1
FT                   /note="M -> V (in Ref. 6; AK064973)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   788 AA;  87590 MW;  76B1A44ED6070021 CRC64;
     MASSLTPRSP YPKKENLGNA RRGMGVKPGP RRNVLSAINN GGGTNSDTAS VDGGEGGAGP
     AAPVIEFTGR EDVERLLAEK MKGKSKTDYK GRTEQMSEYI KKLRACIRWY IELEDGYLVE
     QEKLRSTMDA ENAQHAKLEA QLSSDLEELK AAHLNLTRQC DSLEESFNKE KADRMLAVES
     YEKERQQRES AEASLDLLSV DLERVSHEAK RFSEQLKMVQ DTNKRLQEYN TSLQQYNSNL
     QADASKSGDI ISKLQKEKSA MMETMASLKD LNNSMKNHLD SSRTSQQEAI RMKEQLMKEV
     DCLRIELHQI REDRDQSVSQ VNTLSAELAN YKELAGKSTK DCESLSVKVS AFEETCSMQQ
     EQIQTLQKQL AVATNKLKLA DVTAIEAMTG YEEQKVIIKD LEERLASAEF QIVEADKLRK
     KLHNTILELK GNIRVFCRVR PLLQDNDSSG AEEALISYPT SVESAGRGID LMNQGQRFSF
     SYDKVFDHGA SQEDVFVEMS QLVQSALDGY KVCIFAYGQT GSGKTYTMMG PPGRDQKGII
     PRSLEQIFKT SQSLESQGWK YSMQASMLEI YNETIRDLLA PGRSNNFDLS TSKQYTIKHD
     PQGNTTVTDL TVADVFSSAD VTSLLAKASQ SRSVGRTQMN EQSSRSHFVF TLKISGSNEN
     TGQQVQGVLN LIDLAGSERL AKSGSTGDRL KETQAINKSL SALSDVIFAI AKGDDHVPFR
     NSKLTYLLQP CLGGDSKTLM FVNISPEASS VGETICSLRF ASRVNACEIG IPRRHTQARS
     FDSRLSYG