KN14K_ARATH
ID KN14K_ARATH Reviewed; 975 AA.
AC F4JX00; Q9FHD2;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2016, sequence version 2.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Kinesin-like protein KIN-14K {ECO:0000305};
GN Name=KIN14K {ECO:0000305};
GN OrderedLocusNames=At5g41310 {ECO:0000312|Araport:AT5G41310};
GN ORFNames=K1O13.11 {ECO:0000312|EMBL:BAB11107.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RX PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA Reddy A.S., Day I.S.;
RT "Kinesins in the Arabidopsis genome: a comparative analysis among
RT eukaryotes.";
RL BMC Genomics 2:2-2(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA Richardson D.N., Simmons M.P., Reddy A.S.;
RT "Comprehensive comparative analysis of kinesins in photosynthetic
RT eukaryotes.";
RL BMC Genomics 7:18-18(2006).
RN [6]
RP REVIEW.
RX PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA Zhu C., Dixit R.;
RT "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT motor proteins.";
RL Protoplasma 249:887-899(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-14 subfamily.
CC {ECO:0000303|PubMed:16448571}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AED94663.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAB11107.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB019225; BAB11107.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AB006707; BAB11107.1; JOINED; Genomic_DNA.
DR EMBL; CP002688; AED94663.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; NP_198947.1; NM_123496.2.
DR AlphaFoldDB; F4JX00; -.
DR SMR; F4JX00; -.
DR STRING; 3702.AT5G41310.1; -.
DR PaxDb; F4JX00; -.
DR PeptideAtlas; F4JX00; -.
DR PRIDE; F4JX00; -.
DR GeneID; 834132; -.
DR KEGG; ath:AT5G41310; -.
DR Araport; AT5G41310; -.
DR TAIR; locus:2155095; AT5G41310.
DR eggNOG; KOG0239; Eukaryota.
DR HOGENOM; CLU_001485_1_1_1; -.
DR InParanoid; F4JX00; -.
DR OrthoDB; 364605at2759; -.
DR PRO; PR:F4JX00; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4JX00; baseline and differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0007017; P:microtubule-based process; IBA:GO_Central.
DR Gene3D; 1.10.418.10; -; 1.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR001715; CH-domain.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00033; CH; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF47576; SSF47576; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..975
FT /note="Kinesin-like protein KIN-14K"
FT /id="PRO_0000438046"
FT DOMAIN 40..143
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00044"
FT DOMAIN 436..746
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 289..345
FT /evidence="ECO:0000255"
FT COILED 757..788
FT /evidence="ECO:0000255"
FT COMPBIAS 15..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 520..527
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 975 AA; 109700 MW; 4A86B3D3096B63D8 CRC64;
MKNRIKKGSS MIGVYGRSDG SSSIQSSNGS ESRESIDDNK QGHQSLVEWL NETLPYLNLP
WEASEEELRA CLVDGTVLCN LLNQLSPGSM RMGGSFEPGC VNIERFLAAM DEMTLPRFEV
SDLEQGDMIR VIQSLKALKA SFSDDGYDKN TLSARRRWSL PADHSKGVDS NFNDGGSQFI
EASEINTSHH SLQNTSTRSL FDMLDRLLDE SSQKMNVSHV YVSILRGIVQ VVEQRISNQA
ENLKNQNILF RVREEKYRSR INVLETLASG TTDENEVRRK RCAPNRKGKE RSNAELSKLK
QELEIVKETH EKQFLELKLN AQKAKVELER QVKNSELRVV EAKELEKLCE TKTKRWEKKE
QTYKRFINHQ TEALQELKAT SMSLKHDVLK IGENYFLDLT YYGIKLRGVA HAAKNYQIII
EENRRLYNEV QELKGNIRVY CRIRPFLQGQ NKKQTSIEYT GENGELVVAN PLKQGKDTYR
LFKFNKVFGP ESTQEEVFLD TRPMIRSILD GYNVCIFAYG QTGSGKTYTM SGPSITSEED
RGVNYRALND LFHLTQSRQN SVMYEVGVQM VEIYNEQVRD LLSQDVPDAS MHSVRSTEDV
LELMNIGLMN RTVGATTLNE KSSRSHSVLS VHVRGVDVKT ESVLRGSLHL VDLAGSERVG
RSEVTGERLK EAQHINKSLS ALGDVIFALA HKNPHVPYRN SKLTQVLQNS LGGQAKTLMF
VQINPDEDSY AETVSTLKFA ERVSGVELGA ARSYKEGRDV RQLMEQVSNL KDMIAKKDEE
LQKFQNINGI QKRGLSKLRI VSPPRRHSLG GALTNSPRRR QGPGLLGRTT SDIHRHQNES
RSSSKFSGGA KDNNIFEDTE LLGFEESNNE ERLSDISDSC LSMGTETDGS ISSGAMELTL
FPETSNPPEM FEQSEQNDKA HVGVGPSKPL KHTPKPDISK PSRLSISTTS SKALTSSKRP
VTGISSSVKP LNRKR
