KN14T_ARATH
ID KN14T_ARATH Reviewed; 859 AA.
AC F4I1T9; Q9ZVV2;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Kinesin-like protein KIN-14T {ECO:0000305};
GN Name=KIN14T {ECO:0000305};
GN OrderedLocusNames=At1g55550 {ECO:0000312|Araport:AT1G55550};
GN ORFNames=T5A14.3 {ECO:0000312|EMBL:AAD10640.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA Reddy A.S., Day I.S.;
RT "Kinesins in the Arabidopsis genome: a comparative analysis among
RT eukaryotes.";
RL BMC Genomics 2:2-2(2001).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA Richardson D.N., Simmons M.P., Reddy A.S.;
RT "Comprehensive comparative analysis of kinesins in photosynthetic
RT eukaryotes.";
RL BMC Genomics 7:18-18(2006).
RN [5]
RP REVIEW.
RX PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA Zhu C., Dixit R.;
RT "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT motor proteins.";
RL Protoplasma 249:887-899(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-14 subfamily.
CC {ECO:0000303|PubMed:16448571}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD10640.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005223; AAD10640.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33265.1; -; Genomic_DNA.
DR PIR; B96598; B96598.
DR RefSeq; NP_564696.2; NM_104431.3.
DR AlphaFoldDB; F4I1T9; -.
DR SMR; F4I1T9; -.
DR STRING; 3702.AT1G55550.1; -.
DR iPTMnet; F4I1T9; -.
DR PaxDb; F4I1T9; -.
DR PRIDE; F4I1T9; -.
DR ProteomicsDB; 250694; -.
DR EnsemblPlants; AT1G55550.1; AT1G55550.1; AT1G55550.
DR GeneID; 842004; -.
DR Gramene; AT1G55550.1; AT1G55550.1; AT1G55550.
DR KEGG; ath:AT1G55550; -.
DR Araport; AT1G55550; -.
DR TAIR; locus:2193914; AT1G55550.
DR eggNOG; KOG0239; Eukaryota.
DR HOGENOM; CLU_013578_1_0_1; -.
DR InParanoid; F4I1T9; -.
DR OMA; EYRTEDT; -.
DR OrthoDB; 364605at2759; -.
DR PRO; PR:F4I1T9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I1T9; baseline and differential.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..859
FT /note="Kinesin-like protein KIN-14T"
FT /id="PRO_0000438053"
FT DOMAIN 91..411
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 511..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 422..463
FT /evidence="ECO:0000255"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 859 AA; 96715 MW; 5CB2ECFC9583DC41 CRC64;
MERTRSKPVR NLPETIHSLL GLKSHMTSDW VKSVCNIAKN TSSTSKKEED DFVSVDLQSI
RDQLSALTVQ VNDQNKLRRQ ILNEFLDLKG NIRVFCRVKP LGATEKLRPP VASDTRNVII
KLSETKRKTY NFDRVFQPDS SQDDVFLEIE PVIKSVIDGY NACIFAYGQT GTGKTYTMEG
LPNSPGIVPR AIKGLFKQVE ESNHMFTIHF SMLEIYMGNL KDLLLSEATK PISPIPPSLS
IHTDPNGEID IENLVKLKVD DFNEILRLYK VGCRSRATAS TNSNSVSSRS HCMIRVSVTS
LGAPERRRET NKIWLVDLGG SERVLKTRAT GRRFDEGKAI NLSLSALGDV INSLQRKNSH
IPYRNSKLTQ VLKDSLGQDS KTLMLVHISP KEDDLCETIC SLNFATRAKN IHLGQDESTE
EQAKKEAVMM NLQKMMEKIE QEREMSLRKM RNLNETLEKL TGKPHVIEEE EKDVVREVIH
VTPKKPRNKS RRASDVFPSF MRPTASSNRR LSGADFSVTP NSSSFKSRRN SMISVRAESA
CLPVKKKKNR FDSACDSSDR SVSKSTSIMR QNTADDATVY SQDISECDIK LVVSEHKPKP
LQMGPGSATK SRSNISNFEK DVMQKIGGTE FSRINSWLRS QSENRSYVLD KTQLPATHFL
ENLNRSLEKS PTQSFTTEKI TGNELEGIEE TKTNETVVNP TLMLKKLFEL QCLCSAEEED
QILSRFPIPG YEDDDESRYP PILENDGFSQ HIDNEWFGVN NYSADWERDS PATIPLLECE
PDLKQLLPEL GLDRSLKPRG LAVAEGAAPP LLRAQETLGE RGKGPTFMQK LQALCFRILL
GLGFMDVGFG NDFFNGLTK
