ID   KN5B_ORYSJ              Reviewed;        1038 AA.
AC   B9F7C8;
DT   11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT   11-MAY-2016, sequence version 2.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Kinesin-like protein KIN-5B {ECO:0000305};
GN   Name=KIN5B {ECO:0000305};
GN   OrderedLocusNames=Os03g0279832 {ECO:0000305}, LOC_Os03g17164 {ECO:0000305};
GN   ORFNames=OsJ_10359 {ECO:0000312|EMBL:EEE58808.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [4]
RP   REVIEW.
RX   PubMed=16530461; DOI=10.1016/j.tplants.2006.02.004;
RA   Vanstraelen M., Inze D., Geelen D.;
RT   "Mitosis-specific kinesins in Arabidopsis.";
RL   Trends Plant Sci. 11:167-175(2006).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19106179; DOI=10.1093/aob/mcn248;
RA   Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT   "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT   monocots by mining the rice genome.";
RL   Ann. Bot. 103:387-402(2009).
CC   -!- FUNCTION: Responsible for microtubule translocation. May be important
CC       for the organization of phragmoplast-specific arrays of microtubules
CC       (By similarity). Plays an essential role in stabilizing the mitotic
CC       spindle. Required during mitotic cytokinesis (By similarity).
CC       {ECO:0000250|UniProtKB:F4IIS5, ECO:0000250|UniProtKB:O23826}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:F4IIS5}. Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000250|UniProtKB:F4IIS5}. Note=Microtubule-associated.
CC       {ECO:0000250|UniProtKB:F4IIS5}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-5/BimC subfamily.
CC       {ECO:0000303|PubMed:19106179}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEE58808.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000140; EEE58808.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015628923.1; XM_015773437.1.
DR   AlphaFoldDB; B9F7C8; -.
DR   SMR; B9F7C8; -.
DR   STRING; 39947.B9F7C8; -.
DR   PaxDb; B9F7C8; -.
DR   PRIDE; B9F7C8; -.
DR   GeneID; 107278712; -.
DR   KEGG; osa:107278712; -.
DR   OrthoDB; 179272at2759; -.
DR   Proteomes; UP000007752; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072686; C:mitotic spindle; IBA:GO_Central.
DR   GO; GO:0005876; C:spindle microtubule; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IBA:GO_Central.
DR   GO; GO:0090307; P:mitotic spindle assembly; IBA:GO_Central.
DR   GO; GO:0051231; P:spindle elongation; IBA:GO_Central.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50096; IQ; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Cytoplasm; Cytoskeleton; Microtubule;
KW   Motor protein; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..1038
FT                   /note="Kinesin-like protein KIN-5B"
FT                   /id="PRO_0000436272"
FT   DOMAIN          69..410
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1013..1038
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          453..502
FT                   /evidence="ECO:0000255"
FT   BINDING         154..161
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1038 AA;  116605 MW;  0B2E8A3A93A87CF5 CRC64;
     MAQTPNPSRR SLVGPPPHPF LTPRPERRQL ELRWADGGSQ SSARRSGVGL TGGGGGGGGG
     SEMKDCEANV QVVLRCRPLS EEEQRANVQS AISCDDLKRE VTVLHSLFKQ ADKTFTFDKV
     FGPKAQQRSI YDRAVKPIVK DVLEGYNCTV FAFGQTGTGK TYTMEGEMRQ KASELSATAG
     VIPRAVRDIF DILEERKADY SMKVTFLELY NEEITDLLAL EDQSRFPEDR QKRAISLMED
     RKGGAVIRGL EEVVVYSASE IYNLLEHGSA RRRTADTALN KQSSRSHSVF SIYIHVKETT
     VGNQELLKCG RLNLVDLAGS ENIARSGARE GRAREAGEMN KSLLTLGRVI TALVEHSVHV
     PYRDSKLTRL LRESLGGKAK TCIIATVSPS IHCLEETVVT LDYAYRAKSI KNKPEANQKV
     CKSVILKDLY QEMERMKQDV KAAREKNGIY IPQERFALEE AEKKTMRDKI EYLETQNKEL
     KMNIESCKKE YLDLEEAHSR ANISLKEKEF IISNLLHAEQ SIVERAKDIR GALENASGDI
     SALVDKLGRQ SNTEAENKGL LFDFRSQLDH GLDLLHDTVV GCVCEQRQFL ESMNEQNKIY
     FSAKSESTSQ LERRIAKAKD IYASGVQCMN QLANTLHQRS IAHSEQMGLN ILSHATRAAN
     FLAVMVSEAE QVSNDVFKSI SELKELLAFS ADQQEVMFKR DLVSAQVMSK TSIDFFEDIR
     GHASRLIEHM EQSQAESSSQ LLKFEEDFKE LSVREEQAAL DKIAGILAGL TAKKSTMVLD
     CVGQLNGKCR EEQKHLKLQI SNLQKVSDSG GKEAAAYAAK VESQFSEDKL SHCKIKDQME
     DILQQSLKKT VHSVSYWSHT ETSLEHLNKI SVVEADDFIE ETRKENESIL QKMLIVSTQN
     DAKFAAITSD MLTAVKDSHL RDSESRMRIE TVFATSSDHL EMLDTKHSQG TESIRSMTAK
     CLERDYKANS PVRRRPGELM TNAYSLESIE QLRTPVPDLV VKFRSENNLD EVDKGKRYVD
     QGTRTPRSPL MPVNHYNK