KN6_ORYSJ
ID KN6_ORYSJ Reviewed; 919 AA.
AC Q6YU88; A0A0P0VDK0; B9F1N7;
DT 11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT 11-MAY-2016, sequence version 2.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Kinesin-like protein KIN-6 {ECO:0000305};
GN Name=KIN6 {ECO:0000305};
GN OrderedLocusNames=Os02g0101800 {ECO:0000312|EMBL:BAS76519.1},
GN LOC_Os02g01180 {ECO:0000305};
GN ORFNames=B1370C05.21 {ECO:0000312|EMBL:BAD08190.1},
GN OJ1435_F07.11 {ECO:0000312|EMBL:BAD07807.1},
GN OsJ_04995 {ECO:0000312|EMBL:EEE56125.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 18-919.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19106179; DOI=10.1093/aob/mcn248;
RA Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT monocots by mining the rice genome.";
RL Ann. Bot. 103:387-402(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-6 subfamily.
CC {ECO:0000303|PubMed:19106179}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD07807.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD08190.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF07506.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAS76519.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EEE56125.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP004187; BAD07807.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005873; BAD08190.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAF07506.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; BAS76519.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000139; EEE56125.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK102833; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015627349.1; XM_015771863.1.
DR AlphaFoldDB; Q6YU88; -.
DR SMR; Q6YU88; -.
DR STRING; 4530.OS02T0101800-01; -.
DR PaxDb; Q6YU88; -.
DR PRIDE; Q6YU88; -.
DR GeneID; 4327984; -.
DR KEGG; osa:4327984; -.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_001485_18_0_1; -.
DR InParanoid; Q6YU88; -.
DR OrthoDB; 604899at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; PTHR24115; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..919
FT /note="Kinesin-like protein KIN-6"
FT /id="PRO_0000436275"
FT DOMAIN 72..415
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..57
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 171..178
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT CONFLICT 132
FT /note="G -> D (in Ref. 5; AK102833)"
FT /evidence="ECO:0000305"
FT CONFLICT 144
FT /note="H -> N (in Ref. 5; AK102833)"
FT /evidence="ECO:0000305"
FT CONFLICT 527
FT /note="K -> E (in Ref. 5; AK102833)"
FT /evidence="ECO:0000305"
FT CONFLICT 734
FT /note="H -> R (in Ref. 5; AK102833)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 919 AA; 101155 MW; 9576E4B76C7753C1 CRC64;
MVRLSTKPPN PKVEMNLKEP PITGAGAGAA ASPPAPSTLR RNPPRSARPP PTPLPNSKPS
QISRLLEEAA ERLKVFLRIR PLPLPERKGK AKSPTNPKQV CLVANSPNSV ALTVPHSKLL
DPKRGRTEVF DGFSSVFSPD SSQHDVFSQV MNPLVDDLLL GGKSGLLVAM GPTGSGKTHT
VFGSPRNPGL VPLTLRRIFS PTTHEPFSKL RSFCFSMFEI LSEGKGERIL DLLSDATDLV
LQQSTIKGLK EVSVENFADA EALLFSGMLK RTTAATNANS KSSRSQCIIT IRAVHKSSDA
ESENSLNNAV LTIADLAGAE RERRTGNQGT RLLESNFINN TSMVFGLCLR SLLEHQKNKK
KPLEKHFKNS MLTRYLRDYL EGRKKMTLIL NVKPGDDDYL DTSFLLRQAS PYMKIKYTNL
EDSSGLVSQK RSSASLICQE NTKKRKIHKV AGKDDIDKDD GVTISEKDES QYKLLNSELR
RVSRNEEIMT NFARALWTVL KQYKQKLLES ENAVESTREL LRSKDIKIME LEKKLKVLSC
SCKKFPAVED TFVEQNNDVS SGQVAQSFVS LSSQTDLVSI DSALNKSLAV EEVSEESTGH
GPERSSDYDD KTGTGGSDVC DTSIIKLIAE EELCSGDCKP EKASSSDAFI PEHDVEKENI
GIVVQVLDKK LDRSESCSDG GGVTHSSSSL DHPSDQSFTD TCLQNESANL SPQFIGASKK
SPIEQSEEER EEIHNITTEG IQQNVHTRGV KHHSTPSCSQ EVNSGSLHVS SSQLQGMGAL
QQDPQSERCK PTVEITIVEY GCAQPPHVVD DHGGMYPCTL NGKSSPRKAP ISPTKDNQAE
KLTDKIEDLS ASKPCNRKNT RRRLQPVSAM MLKEFTGPDI FVDTRKEEKV KSSRDAMGRS
DKLIRLLTDH PPRARGRAQ
