KN7E_ARATH
ID KN7E_ARATH Reviewed; 862 AA.
AC F4IGL2; Q56YQ6; Q9SJU7;
DT 08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Kinesin-like protein KIN-7E {ECO:0000305};
GN Name=KIN7E {ECO:0000305};
GN OrderedLocusNames=At2g21300 {ECO:0000312|Araport:AT2G21300};
GN ORFNames=F3K23.6 {ECO:0000312|EMBL:AAD23678.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA Reddy A.S., Day I.S.;
RT "Kinesins in the Arabidopsis genome: a comparative analysis among
RT eukaryotes.";
RL BMC Genomics 2:2-2(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA Richardson D.N., Simmons M.P., Reddy A.S.;
RT "Comprehensive comparative analysis of kinesins in photosynthetic
RT eukaryotes.";
RL BMC Genomics 7:18-18(2006).
RN [6]
RP REVIEW.
RX PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA Zhu C., Dixit R.;
RT "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT motor proteins.";
RL Protoplasma 249:887-899(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-7 subfamily.
CC {ECO:0000303|PubMed:16448571}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD23678.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD93933.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC006841; AAD23678.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC07157.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07158.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62417.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62418.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62419.1; -; Genomic_DNA.
DR EMBL; AK221265; BAD93933.1; ALT_FRAME; mRNA.
DR PIR; F84599; F84599.
DR RefSeq; NP_001031385.1; NM_001036308.2.
DR RefSeq; NP_001324575.1; NM_001335743.1.
DR RefSeq; NP_001324576.1; NM_001335742.1.
DR RefSeq; NP_001324577.1; NM_001335741.1.
DR RefSeq; NP_179726.2; NM_127702.4.
DR AlphaFoldDB; F4IGL2; -.
DR SMR; F4IGL2; -.
DR STRING; 3702.AT2G21300.1; -.
DR iPTMnet; F4IGL2; -.
DR PaxDb; F4IGL2; -.
DR PRIDE; F4IGL2; -.
DR ProteomicsDB; 238204; -.
DR EnsemblPlants; AT2G21300.1; AT2G21300.1; AT2G21300.
DR EnsemblPlants; AT2G21300.2; AT2G21300.2; AT2G21300.
DR EnsemblPlants; AT2G21300.3; AT2G21300.3; AT2G21300.
DR EnsemblPlants; AT2G21300.4; AT2G21300.4; AT2G21300.
DR EnsemblPlants; AT2G21300.5; AT2G21300.5; AT2G21300.
DR GeneID; 816669; -.
DR Gramene; AT2G21300.1; AT2G21300.1; AT2G21300.
DR Gramene; AT2G21300.2; AT2G21300.2; AT2G21300.
DR Gramene; AT2G21300.3; AT2G21300.3; AT2G21300.
DR Gramene; AT2G21300.4; AT2G21300.4; AT2G21300.
DR Gramene; AT2G21300.5; AT2G21300.5; AT2G21300.
DR KEGG; ath:AT2G21300; -.
DR Araport; AT2G21300; -.
DR TAIR; locus:2050115; AT2G21300.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_013407_1_0_1; -.
DR InParanoid; F4IGL2; -.
DR OMA; WETCYIS; -.
DR OrthoDB; 185841at2759; -.
DR PRO; PR:F4IGL2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4IGL2; baseline and differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR021881; NACK_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF11995; DUF3490; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Isopeptide bond; Microtubule; Motor protein;
KW Nucleotide-binding; Reference proteome; Ubl conjugation.
FT CHAIN 1..862
FT /note="Kinesin-like protein KIN-7E"
FT /id="PRO_0000436463"
FT DOMAIN 24..346
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 463..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 355..428
FT /evidence="ECO:0000255"
FT COMPBIAS 465..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 110..117
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT CROSSLNK 734
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in ubiquitin)"
FT /evidence="ECO:0000250|UniProtKB:F4JQ51"
SQ SEQUENCE 862 AA; 96671 MW; 9A12AD6EF154A8D8 CRC64;
MGAIAGEELK KMEKTQVHVA REEKILVLVR LRPLNEKEIL ANEAADWECI NDTTVLYRNT
LREGSTFPSA YSFDRVYRGE CPTRQVYEDG PKEVALSVVK GINSSIFAYG QTSSGKTYTM
SGITEFAVAD IFDYIFKHED RAFVVKFSAI EIYNEAIRDL LSPDSTPLRL RDDPEKGAAV
EKATEETLRD WNHLKELISV CEAQRKIGET SLNERSSRSH QIIKLTVESS AREFLGKENS
TTLMASVNFI DLAGSERASQ ALSAGARLKE GCHINRSLLT LGTVIRKLSN GRQGHINYRD
SKLTRILQPC LGGNARTAIV CTLSPARSHV EQTRNTLLFA CCAKEVTTKA QINVVMSDKA
LVKQLQRELA RLESELRNPA PATSSCDCGV TLRKKDLQIQ KMEKQLAEMT KQRDIAQSRL
EDFMKMVEHD ASSKAGTPHF RNRTNKWEDG SVSEISGVVD PDRTSFISDG TSTPLSTARA
HVRSHSDDDL EEEMSPRHSG DQSEEYCKEV QCIEMEESTR DINNDSEERT DAETLLGHNA
EANGETGSAQ HRIPSSVRSV RRRKSWSRGD TMTGTSTPPD ALETDYRGRP EGHGFAFPDL
EFGSGGKLLR NDSMTSRGSD STEAHSIGTP LVGEEGGITS IRSFVEGLKE MVSDPENSGK
MRKDIGVDAM EEEVSGTMTN WSEEFERQRE QILGLWQTCH VSLVHRTYFF LLFTGDQADS
IYIGVELRRL SFMKESFSQG NHAFERGQTL TIASSLKALH RERRMLSKLV GKRFTGEERK
RLYQKFGIAV NSKRRRLQLA NQLWSKPNDI THAVESAAVV AKLVRFVEQG RAMKEMFGLS
FTPPLPTTRR SLNWRKSMAT LF
