ID   KN7F_ORYSJ              Reviewed;         945 AA.
AC   Q7X7H4; Q7FB17;
DT   06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 2.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Kinesin-like protein KIN-7F {ECO:0000305};
GN   Name=KIN7F {ECO:0000305}; Synonyms=K23 {ECO:0000303|PubMed:21278385};
GN   OrderedLocusNames=Os04g0538800 {ECO:0000312|EMBL:BAF15347.1},
GN   LOC_Os04g45580 {ECO:0000305};
GN   ORFNames=OsJ_15615 {ECO:0000312|EMBL:EEE61418.1},
GN   OSJNBa0011L07.1 {ECO:0000312|EMBL:CAE02777.2},
GN   OSJNBa0091D06.23 {ECO:0000312|EMBL:CAE03025.3},
GN   OSNPB_040538800 {ECO:0000312|EMBL:BAS90272.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19106179; DOI=10.1093/aob/mcn248;
RA   Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT   "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT   monocots by mining the rice genome.";
RL   Ann. Bot. 103:387-402(2009).
RN   [8]
RP   FUNCTION, ATP-BINDING, AND SUBUNIT.
RX   PubMed=21278385; DOI=10.1093/jb/mvr012;
RA   Umezu N., Hanzawa N., Yamada M.D., Kondo K., Mitsui T., Maruta S.;
RT   "Biochemical characterization of the novel rice kinesin K23 and its kinetic
RT   study using fluorescence resonance energy transfer between an intrinsic
RT   tryptophan residue and a fluorescent ATP analogue.";
RL   J. Biochem. 149:539-550(2011).
CC   -!- FUNCTION: Binds ATP/ADP in vitro. Possesses low ATPase activity but
CC       high affinity for microtubules. {ECO:0000269|PubMed:21278385}.
CC   -!- SUBUNIT: Binds microtubules. {ECO:0000269|PubMed:21278385}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-7 subfamily.
CC       {ECO:0000303|PubMed:19106179}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAE03025.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL606459; CAE03025.3; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL606587; CAE02777.2; -; Genomic_DNA.
DR   EMBL; AP008210; BAF15347.1; -; Genomic_DNA.
DR   EMBL; AP014960; BAS90272.1; -; Genomic_DNA.
DR   EMBL; CM000141; EEE61418.1; -; Genomic_DNA.
DR   EMBL; AK102262; BAG95469.1; -; mRNA.
DR   RefSeq; XP_015636528.1; XM_015781042.1.
DR   AlphaFoldDB; Q7X7H4; -.
DR   SMR; Q7X7H4; -.
DR   STRING; 4530.OS04T0538800-01; -.
DR   iPTMnet; Q7X7H4; -.
DR   PaxDb; Q7X7H4; -.
DR   PRIDE; Q7X7H4; -.
DR   EnsemblPlants; Os04t0538800-01; Os04t0538800-01; Os04g0538800.
DR   GeneID; 4336528; -.
DR   Gramene; Os04t0538800-01; Os04t0538800-01; Os04g0538800.
DR   KEGG; osa:4336528; -.
DR   eggNOG; KOG0242; Eukaryota.
DR   HOGENOM; CLU_013407_0_0_1; -.
DR   InParanoid; Q7X7H4; -.
DR   OMA; GRPQNCQ; -.
DR   OrthoDB; 185841at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000007752; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IDA:UniProtKB.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR021881; NACK_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF11995; DUF3490; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..945
FT                   /note="Kinesin-like protein KIN-7F"
FT                   /id="PRO_0000436627"
FT   DOMAIN          34..356
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          484..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          553..588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          365..437
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        493..512
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         120..127
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   945 AA;  105470 MW;  A00874A5FD5E44F6 CRC64;
     MGAIGGDEVV QWDKMDGGEV VNGGGGGGVG KLERILVSVR LRPLSDKEIA RGDPSEWECI
     NDTTIISRST FPDRPSAPTA YSFDRVFRSD CDTNEVYKQG AKEVALSVVS GINSSIFAYG
     QTSSGKTYTM TGITEYTVAD IYDYIGKHEE RAFVLKFSAI EIYNEVVRDL LSAENTPLRL
     WDDAEKGTYV ENLTEVVLRD WNHLKELISV CEAQRKTGET YLNENSSRSH QILKLTIESS
     AREFLGKDKS TTLVASVNFV DLAGSERASQ ALSAGARLKE GCHINRSLLT LGTVIRKLSK
     VRNGHIPYRD SKLTRILQPS LGGNARTAII CTMSPARSHM EQSRNTLLFA SCAKEVVTNA
     QVNVVMSDKA LVKQLQKELA RLESELRCPA SYSSLESLVK EKDNQIRKME KEIKELKLQR
     DLAQSRLQDL LQVVGDNHVH VSKQSSVSGR NFTFDVPQTC EDEQSTTESS EVVDSVQNFR
     FQGRRVAQRE HKPQQAENNV QFTTPSRYSV SSPPFSGMLP TNRSDHLSQI SNEDSDDICK
     EVRCIETNET GGNECLESSA VGSNSLQDPN AGSSMHINND SNSSMNSRLR DESPVTLEQH
     LENVRKPFAN IVKDLGSSTR NSSSSKVLGR SRSCRSLTGS SLFEDLEKDD CTPPNRSFID
     FAGRPQNCQR RGSALNYDAE SETLSRAGSM LSEITTTRDG LKANSSVAGD TEFTGIGEFV
     AELKEMAQVQ YQKQLGHSGN GDLAEGTIRS VGLDPITDAL QSPSRWPLEF EKKQQEIIDF
     WHACNVSLVH RTYFFLLFKG DPADSIYMEV ELRRLSFLKD TYSNGAIASI PNTSLVSSAK
     KLQREREMLC RQMQRRLSIE ERESMYTKWG VSLASKRRRL QVARCLWTET KDLEHVRESA
     SLVARLIGLL EPGKALREMF GLSFAPQQFT RRSYNSWRYG RSSLN