KN7H_ARATH
ID KN7H_ARATH Reviewed; 1063 AA.
AC F4JZ68; Q94JU6; Q9FH58;
DT 08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Kinesin-like protein KIN-7H {ECO:0000305};
GN Name=KIN7H {ECO:0000305};
GN OrderedLocusNames=At5g66310 {ECO:0000312|Araport:AT5G66310};
GN ORFNames=K1L20.9 {ECO:0000312|EMBL:BAB10710.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-425.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA Reddy A.S., Day I.S.;
RT "Kinesins in the Arabidopsis genome: a comparative analysis among
RT eukaryotes.";
RL BMC Genomics 2:2-2(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA Richardson D.N., Simmons M.P., Reddy A.S.;
RT "Comprehensive comparative analysis of kinesins in photosynthetic
RT eukaryotes.";
RL BMC Genomics 7:18-18(2006).
RN [6]
RP REVIEW.
RX PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA Zhu C., Dixit R.;
RT "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT motor proteins.";
RL Protoplasma 249:887-899(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-7 subfamily.
CC {ECO:0000303|PubMed:16448571}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10710.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB022211; BAB10710.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED98197.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68962.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68963.1; -; Genomic_DNA.
DR EMBL; AF372930; AAK50070.1; -; mRNA.
DR RefSeq; NP_001318888.1; NM_001345755.1.
DR RefSeq; NP_001330675.1; NM_001345756.1.
DR RefSeq; NP_201432.2; NM_126029.3.
DR AlphaFoldDB; F4JZ68; -.
DR SMR; F4JZ68; -.
DR IntAct; F4JZ68; 1.
DR STRING; 3702.AT5G66310.1; -.
DR iPTMnet; F4JZ68; -.
DR PaxDb; F4JZ68; -.
DR PRIDE; F4JZ68; -.
DR ProteomicsDB; 238207; -.
DR EnsemblPlants; AT5G66310.1; AT5G66310.1; AT5G66310.
DR EnsemblPlants; AT5G66310.2; AT5G66310.2; AT5G66310.
DR EnsemblPlants; AT5G66310.3; AT5G66310.3; AT5G66310.
DR GeneID; 836763; -.
DR Gramene; AT5G66310.1; AT5G66310.1; AT5G66310.
DR Gramene; AT5G66310.2; AT5G66310.2; AT5G66310.
DR Gramene; AT5G66310.3; AT5G66310.3; AT5G66310.
DR KEGG; ath:AT5G66310; -.
DR Araport; AT5G66310; -.
DR TAIR; locus:2155051; AT5G66310.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_013407_0_0_1; -.
DR InParanoid; F4JZ68; -.
DR OMA; CTRQVYE; -.
DR OrthoDB; 99288at2759; -.
DR PRO; PR:F4JZ68; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4JZ68; baseline and differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR021881; NACK_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF11995; DUF3490; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..1063
FT /note="Kinesin-like protein KIN-7H"
FT /id="PRO_0000436466"
FT DOMAIN 18..342
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 574..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 351..436
FT /evidence="ECO:0000255"
FT BINDING 106..113
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1063 AA; 121424 MW; 8F1443F6FBDFF736 CRC64;
MTTEDDDQML GPSGTQEKIY VSVRMRPLND KEKFRNDVPD WECINNTTII YRSHLSISER
SMYPSAYTFD RVFSPECCTR QVYEQGAKEV AFSVVSGVNA SVFAYGQTSS GKTYTMSGIT
DCALVDIYGY IDKHKEREFI LKFSAMEIYN ESVRDLLSTD TSPLRLLDDP EKGTVVEKLT
EETLRDWNHF KELLSVCKAQ RQIGETALNE VSSRSHQILR LTVESIAREF STNDKFSTLT
ATVNFIDLAG SERASQSLSA GTRLKEGCHI NRSLLTLGTV IRKLSKEKTG HIPFRDSKLT
RILQSSLGGN ARTAIICTMS PARIHVEQSR NTLLFASCAK EVTTNAQVNV VMSDKALVKH
LQRELAKLES ELRSPSQASI VSDTTALLTE KDLEVEKLKK EVFQLAQQLE QARSEIKDLR
RMVEEEKNQE KETLSTETEG LNVLMEHQYP KLRVRRTWDS ENTTPLSPIS AHRSSISPRS
TEYSYEENVF QLSDFRIDSA SSSPQQLAFV TPFLKVPLDD IHVTDTVDQS HVHKEEAIEE
PHVQEERFYE MAEHTDGNSE DNCREVRCIE TEKSDISIGP VENMPESSPD KYEAVTAEEP
VSVTEPKNLQ HPTEEAVCVT ETKNLQHPTE AENEEEEEEE RVKEVSGASP EPKQESNLTK
NPALCDLECS PDEFDTSMSN LSRISTPPAL ITPSPEKPFS WIMERDSQLF RGMKLTRSRS
CRPSLLSSPS SSWLEKDADT PPSWYDKEFI KTAERNLTMC DIKNQRLLQD EFSGRSMPTT
WFERSLSDTQ TVDAASHGVS NEMSPNESPF RPSDASVFEL QTSGRASISQ DRTEETAAQK
DKQIIHRSME EREQKFLASN STKSFKDAAM DPIQDYLDTA LNWPVEFKRL QREIIELWHV
CKVSMAHRSY FFLLFRGDQK DCLYLEVELR RLKYIRESFA QNSNDGNNMT LISCTRALTR
ERYKLSKLMQ RKLSKEEREN LFLRWGIGLN TNHRRVQLAR RLWSDYKDMG HVRESASLVG
KLNGFVDMKL TSTEMFGVNY AFRPPRPKKS SLWKRSVLSL SFL
