KN7N_ARATH
ID KN7N_ARATH Reviewed; 823 AA.
AC Q9S7P3; Q94HV9; Q9LQ62;
DT 08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Kinesin-like protein KIN-7N {ECO:0000305};
GN Name=KIN7N {ECO:0000305}; Synonyms=ZCF125 {ECO:0000312|EMBL:BAA88114.1};
GN OrderedLocusNames=At1g59540 {ECO:0000312|Araport:AT1G59540};
GN ORFNames=T30E16.9 {ECO:0000312|EMBL:AAF79747.1},
GN T4M14.11 {ECO:0000312|EMBL:AAK62792.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10548732; DOI=10.1016/s0378-1119(99)00403-5;
RA Kato A., Suzuki M., Kuwahara A., Ooe H., Higano-Inaba K., Komeda Y.;
RT "Isolation and analysis of cDNA within a 300 kb Arabidopsis thaliana
RT genomic region located around the 100 map unit of chromosome 1.";
RL Gene 239:309-316(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RX PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA Reddy A.S., Day I.S.;
RT "Kinesins in the Arabidopsis genome: a comparative analysis among
RT eukaryotes.";
RL BMC Genomics 2:2-2(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA Richardson D.N., Simmons M.P., Reddy A.S.;
RT "Comprehensive comparative analysis of kinesins in photosynthetic
RT eukaryotes.";
RL BMC Genomics 7:18-18(2006).
RN [6]
RP REVIEW.
RX PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA Zhu C., Dixit R.;
RT "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT motor proteins.";
RL Protoplasma 249:887-899(2012).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9S7P3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-7 subfamily.
CC {ECO:0000303|PubMed:16448571}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79747.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAK62792.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB028468; BAA88112.1; -; mRNA.
DR EMBL; AB028470; BAA88114.1; -; Genomic_DNA.
DR EMBL; AC009317; AAF79747.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC027036; AAK62792.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33586.1; -; Genomic_DNA.
DR PIR; D96619; D96619.
DR PIR; T52425; T52425.
DR RefSeq; NP_564744.1; NM_104648.4. [Q9S7P3-1]
DR AlphaFoldDB; Q9S7P3; -.
DR SMR; Q9S7P3; -.
DR STRING; 3702.AT1G59540.1; -.
DR PaxDb; Q9S7P3; -.
DR PRIDE; Q9S7P3; -.
DR ProteomicsDB; 237141; -. [Q9S7P3-1]
DR EnsemblPlants; AT1G59540.1; AT1G59540.1; AT1G59540. [Q9S7P3-1]
DR GeneID; 842245; -.
DR Gramene; AT1G59540.1; AT1G59540.1; AT1G59540. [Q9S7P3-1]
DR KEGG; ath:AT1G59540; -.
DR Araport; AT1G59540; -.
DR TAIR; locus:2202862; AT1G59540.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_001485_25_1_1; -.
DR InParanoid; Q9S7P3; -.
DR OMA; ACWKEKL; -.
DR OrthoDB; 92916at2759; -.
DR PhylomeDB; Q9S7P3; -.
DR PRO; PR:Q9S7P3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9S7P3; baseline and differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Coiled coil; Microtubule; Motor protein;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1..823
FT /note="Kinesin-like protein KIN-7N"
FT /id="PRO_0000436472"
FT DOMAIN 3..325
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT COILED 341..414
FT /evidence="ECO:0000255"
FT COILED 527..557
FT /evidence="ECO:0000255"
FT COILED 696..786
FT /evidence="ECO:0000255"
FT BINDING 83..90
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 823 AA; 93149 MW; 6AFB1C622E4632C9 CRC64;
MEKICVAVRV RPPAPENGAS LWKVEDNRIS LHKSLDTPIT TASHAFDHVF DESSTNASVY
ELLTKDIIHA AVEGFNGTAF AYGQTSSGKT FTMTGSETDP GIIRRSVRDV FERIHMISDR
EFLIRVSYME IYNEEINDLL AVENQRLQIH EHLERGVFVA GLKEEIVSDA EQILKLIDSG
EVNRHFGETN MNVHSSRSHT IFRMVIESRG KDNSSSDAIR VSVLNLVDLA GSERIAKTGA
GGVRLQEGKY INKSLMILGN VINKLSDSTK LRAHIPYRDS KLTRILQPAL GGNAKTCIIC
TIAPEEHHIE ESKGTLQFAS RAKRITNCAQ VNEILTDAAL LKRQKLEIEE LRMKLQGSHA
EVLEQEILNL SNQMLKYELE CERLKTQLEE EKRKQKEQEN CIKEQQMKIE NLNNFVTNSD
FKRNQSEDFI ISRKTPDGLC NVNDTSDVPG TPCFKSASRS FVVARSNNYS GLSDFSPMVH
SLGDVADEDT WMKLNKGFVA DLDQIQFTPA VKCQPTPLSI ATTECPRENH SEVEDLKSRI
QLLTNENDSL QVKFNEQVLL SNNLMQEMSE LKQETLTVKE IPNRLSESVA NCKDVYKDVI
VTMKSLITDK ESPTANLLLG TTEITTSLLA TLETQFSMIM DGQKTGSSID HPLSDHWETL
RVNLKNTTTL LLSDAQAKDE FLNSHNKGQE TAALEEKKLK SELIIIKERY NELEKELCLD
KQLLEASRES HEKLIKEVQF LKEERDSLDR KISQSTQRLR VIASDKENAL KDLNVEVKRR
KDMEEEIKHI SIAFATRHKS FVSFHSEIKS KMQKLTTQNS KAP
