ID   KN7O_ARATH              Reviewed;        1273 AA.
AC   F4J2K4; Q9SS29; Q9SS30;
DT   08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Kinesin-like protein KIN-7O {ECO:0000305};
GN   Name=KIN7O {ECO:0000305};
GN   OrderedLocusNames=At3g10180/At3g10170 {ECO:0000312|Araport:AT3G10180};
GN   ORFNames=F14P13.23/F14P13.22 {ECO:0000312|EMBL:AAF02823.1,
GN   ECO:0000312|EMBL:AAF02824.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=11472632; DOI=10.1186/1471-2164-2-2;
RA   Reddy A.S., Day I.S.;
RT   "Kinesins in the Arabidopsis genome: a comparative analysis among
RT   eukaryotes.";
RL   BMC Genomics 2:2-2(2001).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16448571; DOI=10.1186/1471-2164-7-18;
RA   Richardson D.N., Simmons M.P., Reddy A.S.;
RT   "Comprehensive comparative analysis of kinesins in photosynthetic
RT   eukaryotes.";
RL   BMC Genomics 7:18-18(2006).
RN   [5]
RP   REVIEW.
RX   PubMed=22038119; DOI=10.1007/s00709-011-0343-9;
RA   Zhu C., Dixit R.;
RT   "Functions of the Arabidopsis kinesin superfamily of microtubule-based
RT   motor proteins.";
RL   Protoplasma 249:887-899(2012).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. KIN-7 subfamily.
CC       {ECO:0000303|PubMed:16448571}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF02823.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At3g10170 and At3g10180.; Evidence={ECO:0000305};
CC       Sequence=AAF02824.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At3g10170 and At3g10180.; Evidence={ECO:0000305};
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DR   EMBL; AC009400; AAF02823.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC009400; AAF02824.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE74868.1; -; Genomic_DNA.
DR   RefSeq; NP_187629.3; NM_111853.4.
DR   AlphaFoldDB; F4J2K4; -.
DR   SMR; F4J2K4; -.
DR   IntAct; F4J2K4; 1.
DR   STRING; 3702.AT3G10180.1; -.
DR   iPTMnet; F4J2K4; -.
DR   PaxDb; F4J2K4; -.
DR   PRIDE; F4J2K4; -.
DR   ProteomicsDB; 250764; -.
DR   EnsemblPlants; AT3G10180.1; AT3G10180.1; AT3G10180.
DR   GeneID; 820180; -.
DR   Gramene; AT3G10180.1; AT3G10180.1; AT3G10180.
DR   KEGG; ath:AT3G10180; -.
DR   Araport; AT3G10180; -.
DR   TAIR; locus:2076294; AT3G10180.
DR   eggNOG; KOG0242; Eukaryota.
DR   HOGENOM; CLU_001485_25_0_1; -.
DR   InParanoid; F4J2K4; -.
DR   OrthoDB; 92916at2759; -.
DR   PRO; PR:F4J2K4; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; F4J2K4; baseline and differential.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..1273
FT                   /note="Kinesin-like protein KIN-7O"
FT                   /id="PRO_0000436473"
FT   DOMAIN          3..327
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT   REGION          452..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          333..408
FT                   /evidence="ECO:0000255"
FT   COILED          602..674
FT                   /evidence="ECO:0000255"
FT   COILED          751..1023
FT                   /evidence="ECO:0000255"
FT   BINDING         79..86
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1273 AA;  144758 MW;  0A965476A3C20261 CRC64;
     MERIHVSVRA RPLSSEDAKT SPWKISSDSI FMPNHSSLAF EFDRIFREDC KTVQVYEART
     KEIVSAAVRG FNGTVFAYGQ TNSGKTHTMR GSPIEPGVIP LAVHDLFDTI YQDASREFLL
     RMSYLEIYNE DINDLLAPEH RKLQIHENLE KGIFVAGLRE EIVASPQQVL EMMEFGESHR
     HIGETNMNLY SSRSHTIFRM IIESRQKMQD EGVGNSCDAV RVSVLNLVDL AGSERAAKTG
     AEGVRLKEGS HINKSLMTLG TVIKKLSEGV ETQGGHVPYR DSKLTRILQP ALGGNANTAI
     ICNITLAPIH ADETKSSLQF ASRALRVTNC AHVNEILTDA ALLKRQKKEI EELRSKLKTS
     HSDHSEEEIL NLRNTLLKSE LERERIALEL EEEKKAQAQR ERVLQEQAKK IKNLSSMVLL
     SNRDEKREQD HFKKGKRRDT WCIGKLSRDS TSEDQSNVLS RGSSLESARS ERETGPLLPF
     SELVNEPLYN INEEDEDSIE GTLEDSVLPD PCALVNVTSR KKPSIKQKNP VVVENELDRI
     QREYEALLLQ YETERIISEI QIECLKVKLG EDGLSGDAKC KQSEVVGNVH CEEHVVNLRD
     PEAILLIKQL QEKINMLELE KSSSNRNLDD LVMVATEQNI CAREKFAEIQ EEIHAAREEA
     QVAREQLVSK ESEVIDVINE NFNSLVNVAT EIEVLESEFQ KYKASVETIS SVMNEGLQDF
     AFFSPLIHDF TLFVRQSSEQ HDSLINSYQT VQSSLKKKVL DVENEKLLLQ EQCAGLQSQI
     EELNQEAQKH ETSLKMLSEH HESERSDLLS HIECLEKDIG SLSSSSLAKE KENLRKDFEK
     TKTKLKDTES KLKNSMQDKT KLEAEKASAE RELKRLHSQK ALLERDISKQ ESFAGKRRDS
     LLVERSANQS LQEEFKQLEV LAFEMETTIA SLEEELAAER GEKEEALCRN DGLGSEITDL
     TEKLEHSNTK LEHLQNDVTE LKTRLEVSSS DQQQLETNVK QLLEEKEELA MHLANSLLEM
     EEEKAIWSSK EKALTEAVEE KIRLYKNIQI ESLSKEMSEE KKELESCRLE CVTLADRLRC
     SEENAKQDKE SSLEKSLEID RLGDELRSAD AVSKQSQEVL KSDIDILKSE VQHACKMSDT
     FQREMDYVTS ERQGLLARIE ELSKELASSN RWQIENAKNP IQDLTLKISS QETNLHKDAA
     AENKEKAKLK MRLRGMQARL DAISLRYKQS VQESELMNRK FKEASAKLKE KLASKALEVL
     DLKKQLSASS RTM