KN8A_ORYSJ
ID KN8A_ORYSJ Reviewed; 776 AA.
AC Q0JLE4; A0A0P0V508; A2ZV76;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 07-SEP-2016, sequence version 3.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Kinesin-like protein KIN-8A {ECO:0000305};
GN Name=KIN8A {ECO:0000305};
GN OrderedLocusNames=Os01g0605500 {ECO:0000312|EMBL:BAS73064.1},
GN LOC_Os01g42070 {ECO:0000305};
GN ORFNames=OsJ_02534 {ECO:0000312|EMBL:EAZ12623.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19106179; DOI=10.1093/aob/mcn248;
RA Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT monocots by mining the rice genome.";
RL Ann. Bot. 103:387-402(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-8 subfamily.
CC {ECO:0000303|PubMed:19106179}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF05434.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAZ12623.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP008207; BAF05434.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; BAS73064.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ12623.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015632112.1; XM_015776626.1.
DR AlphaFoldDB; Q0JLE4; -.
DR SMR; Q0JLE4; -.
DR STRING; 4530.OS01T0605500-00; -.
DR PRIDE; Q0JLE4; -.
DR EnsemblPlants; Os01t0605500-00; Os01t0605500-00; Os01g0605500.
DR GeneID; 4324211; -.
DR Gramene; Os01t0605500-00; Os01t0605500-00; Os01g0605500.
DR KEGG; osa:4324211; -.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_009927_0_0_1; -.
DR InParanoid; Q0JLE4; -.
DR OMA; RSCVKIV; -.
DR OrthoDB; 703086at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Microtubule; Motor protein; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..776
FT /note="Kinesin-like protein KIN-8A"
FT /id="PRO_0000437030"
FT DOMAIN 205..534
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 554..592
FT /evidence="ECO:0000255"
FT COILED 634..671
FT /evidence="ECO:0000255"
FT COMPBIAS 93..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..133
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 297..304
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 776 AA; 84419 MW; 373F43DFCE4C7E6A CRC64;
MPVSTRASAA GGQPWSSAAP APASAPGRGG ARREILTNHH HHGLKEKMRA LTLFYEQHKQ
QLASSQGGGA RGRRSIQYAV GEVGGDENGR NAEEEDDVGR KRHDAVPAAV LRENMAPPEE
RAPPPPPAPP PKSSHVVVFS RQADPTEKEN VSHGGIATMS CPIKKAAPAL PAPAARKLSL
GGGMAARLKT AGEAGAGNGD AAGSRIMVFV RLRPMSRKEK DAGSRSCVKI VNKKDVYLTE
FASETDYLRL KRVRGRHFCF DSSFPDTTTQ AEVYSTTTSD LVEGVLQGRN GTVFCYGATG
AGKTYTMLGT MESPGVMVLA IKDLFTKVRQ RSHDGNHSIQ LSYLEVYNET VRDLLSPGRP
LLLREDKQGT VAAGLTHYRA YSTDEVMKLL QQGNQNRTTE PTRVNETSSR SHAILQVIVE
YRSIDGGSIV TRVGKLSLID LAGSERALAT DQRTQRSIEG ANINRSLLAL SSCINALVEG
KKHIPYRNSK LTQLLKDSLG GSCNTVMIAN ISPSNLSFGE TQNTLHWADR AKEIKTKALT
TANEEVLRVT DSETDQAKLV LELQKENSEL RQQLARQQQK LLTVQAQTLA SNASPQQSPA
PSAQISTPCS TQRKVKRSIL AGNCFNTPDS KRPAAENAQV RDLQRKVKAM EAEIEKMKKE
HLLQLKQKDE FIRDLINRKT SNVPEAATCE RRVATRASVR KAQKDAAAAG ELRSPSHRFT
SPVPTAKKRT FWDIGGNSPS TLAVNGRKTR SHVAAETPKG TSMLLQPGFA RQRAIH
