KN8B_ORYSJ
ID KN8B_ORYSJ Reviewed; 735 AA.
AC Q10E64; A0A0P0W485; B9F5Y0; Q7XZX0;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Kinesin-like protein KIN-8B {ECO:0000305};
GN Name=KIN8B {ECO:0000305};
GN OrderedLocusNames=Os03g0773600 {ECO:0000312|EMBL:BAS86614.1},
GN LOC_Os03g56260 {ECO:0000312|EMBL:ABF99106.1};
GN ORFNames=OsJ_12760 {ECO:0000312|EMBL:EEE60013.1},
GN OSJNBb0094O03.14 {ECO:0000312|EMBL:AAP68884.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19106179; DOI=10.1093/aob/mcn248;
RA Guo L., Ho C.M., Kong Z., Lee Y.R., Qian Q., Liu B.;
RT "Evaluating the microtubule cytoskeleton and its interacting proteins in
RT monocots by mining the rice genome.";
RL Ann. Bot. 103:387-402(2009).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q10E64-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q10E64-2; Sequence=VSP_058483;
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-8 subfamily.
CC {ECO:0000303|PubMed:19106179}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAP68884.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAS86615.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC092781; AAP68884.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000009; ABF99106.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF13331.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS86614.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS86615.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000140; EEE60013.1; -; Genomic_DNA.
DR EMBL; AK059632; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK103310; BAG96008.1; -; mRNA.
DR RefSeq; XP_015628207.1; XM_015772721.1. [Q10E64-1]
DR RefSeq; XP_015628208.1; XM_015772722.1. [Q10E64-2]
DR AlphaFoldDB; Q10E64; -.
DR SMR; Q10E64; -.
DR STRING; 4530.OS03T0773600-01; -.
DR PaxDb; Q10E64; -.
DR PRIDE; Q10E64; -.
DR EnsemblPlants; Os03t0773600-01; Os03t0773600-01; Os03g0773600. [Q10E64-1]
DR GeneID; 4334272; -.
DR Gramene; Os03t0773600-01; Os03t0773600-01; Os03g0773600. [Q10E64-1]
DR KEGG; osa:4334272; -.
DR eggNOG; KOG0242; Eukaryota.
DR HOGENOM; CLU_001485_2_10_1; -.
DR InParanoid; Q10E64; -.
DR OMA; MMSECSP; -.
DR OrthoDB; 703086at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0008574; F:plus-end-directed microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; -; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115; PTHR24115; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Coiled coil; Microtubule; Motor protein;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1..735
FT /note="Kinesin-like protein KIN-8B"
FT /id="PRO_0000437031"
FT DOMAIN 14..349
FT /note="Kinesin motor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT REGION 664..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 354..395
FT /evidence="ECO:0000255"
FT COILED 424..454
FT /evidence="ECO:0000255"
FT BINDING 106..113
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00283"
FT VAR_SEQ 721..735
FT /note="VNSLPLYTKTMIGNL -> DSWYTEERQ (in isoform 2)"
FT /id="VSP_058483"
SQ SEQUENCE 735 AA; 82617 MW; A5EADB3A3440ADD6 CRC64;
MPSIRAPASK QTATLQVAVK CRPLTDSEQR RSRHIIQVID DKNVVVLDPD LSKDYLELIQ
NRTKERRYSF DHVYAPGCSN ADVYKNISST IAGVVQGLNA TVFAYGSTGS GKTYTMVGTH
SDPGLMVLSF RTIFDLVKKD DSKDTFEVSC SYLEVYNEVI YDLLEKSSGH LELREDPVHG
IMVAGLRSIK VHSADKILEL LNIGNSRRKT ESTEANSTSS RSHAVLEITV KRKQKGQYGS
QVLRGKLALV DLAGSERASE TNNFGQKLRD GANINRSLLA LANCINALGK QNKKGLAYVP
YRNSKLTRIL KDGLSGNSRT VMVATISPAD DQYHHTTNTL KYADRAKEIK THVHKNIGHL
DTHVEDYKRM IDNLQVEVSQ LKKELAEKEH QLSVKPTEKA ADNELSWLNI LSQETGENVQ
ERINLQKALF ELEETNKRNR MELQHLDDAI ARQQVKDKDS AVLQALTSRR QVILDNIRDN
DEAGAGYRKD IELNESRKRQ LQDMIEEATS NNGNRTYLHI LSQYRLLGMT NAELQIEMAM
RDQVIYNQRE SLRSLWNIIY GTGLNQKQIS KLAAKQGLTI EGCPLPVSSP DVTTPPSFSP
HGRLSPFMSF PSPQSQPYSP SACFVQHGFS TMSYLRNQHE TPTVCRQEHL SSYYMMSECS
PFDGDGKQKT NGRSMPYFST PGKPKEMYNF SPGTESERTP CSKEYPTSYS RNGDSLVQIK
VNSLPLYTKT MIGNL
