KNAT7_ARATH
ID KNAT7_ARATH Reviewed; 291 AA.
AC Q9FPQ8; Q8GXB5; Q8LG94; Q9LQ05;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Homeobox protein knotted-1-like 7;
DE AltName: Full=Protein IRREGULAR XYLEM 11;
DE AltName: Full=Protein KNAT7;
GN Name=KNAT7; Synonyms=IRX11; OrderedLocusNames=At1g62990;
GN ORFNames=F16P17.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11701881; DOI=10.2307/3871587;
RA Bellaoui M., Pidkowich M.S., Samach A., Kushalappa K., Kohalmi S.E.,
RA Modrusan Z., Crosby W.L., Haughn G.W.;
RT "The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through
RT a domain conserved between plants and animals.";
RL Plant Cell 13:2455-2470(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION.
RX PubMed=15980264; DOI=10.1105/tpc.105.031542;
RA Brown D.M., Zeef L.A.H., Ellis J., Goodacre R., Turner S.R.;
RT "Identification of novel genes in Arabidopsis involved in secondary cell
RT wall formation using expression profiling and reverse genetics.";
RL Plant Cell 17:2281-2295(2005).
RN [8]
RP INTERACTION WITH OFP1; OFP2; OFP3; OFP4 AND OFP6.
RX PubMed=15781858; DOI=10.1073/pnas.0501181102;
RA Hackbusch J., Richter K., Muller J., Salamini F., Uhrig J.F.;
RT "A central role of Arabidopsis thaliana ovate family proteins in networking
RT and subcellular localization of 3-aa loop extension homeodomain proteins.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:4908-4912(2005).
CC -!- FUNCTION: May be involved in secondary cell wall biosynthesis.
CC {ECO:0000269|PubMed:15980264}.
CC -!- SUBUNIT: May form heterodimeric complex with the TALE/BELL proteins (By
CC similarity). Interacts with OFP1, OFP2, OFP3, OFP4 and OFP6.
CC {ECO:0000250, ECO:0000269|PubMed:15781858}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC {ECO:0000255|PROSITE-ProRule:PRU00559}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF75812.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAM67281.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAC42940.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF308451; AAG40858.1; -; mRNA.
DR EMBL; AC011000; AAF75812.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE34034.1; -; Genomic_DNA.
DR EMBL; AK118326; BAC42940.1; ALT_INIT; mRNA.
DR EMBL; BT026059; ABG48415.1; -; mRNA.
DR EMBL; AY084398; AAM67281.1; ALT_INIT; mRNA.
DR PIR; A96655; A96655.
DR RefSeq; NP_564805.1; NM_104977.3.
DR AlphaFoldDB; Q9FPQ8; -.
DR SMR; Q9FPQ8; -.
DR BioGRID; 27823; 25.
DR IntAct; Q9FPQ8; 24.
DR STRING; 3702.AT1G62990.1; -.
DR PaxDb; Q9FPQ8; -.
DR PRIDE; Q9FPQ8; -.
DR ProteomicsDB; 238189; -.
DR EnsemblPlants; AT1G62990.1; AT1G62990.1; AT1G62990.
DR GeneID; 842602; -.
DR Gramene; AT1G62990.1; AT1G62990.1; AT1G62990.
DR KEGG; ath:AT1G62990; -.
DR Araport; AT1G62990; -.
DR TAIR; locus:2015554; AT1G62990.
DR eggNOG; KOG0773; Eukaryota.
DR HOGENOM; CLU_040111_1_0_1; -.
DR InParanoid; Q9FPQ8; -.
DR OMA; DISSMMI; -.
DR OrthoDB; 1070344at2759; -.
DR PhylomeDB; Q9FPQ8; -.
DR PRO; PR:Q9FPQ8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FPQ8; baseline and differential.
DR Genevisible; Q9FPQ8; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0010192; P:mucilage biosynthetic process; IMP:TAIR.
DR GO; GO:0080001; P:mucilage extrusion from seed coat; IMP:TAIR.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:2000652; P:regulation of secondary cell wall biogenesis; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0010214; P:seed coat development; IMP:TAIR.
DR GO; GO:0080112; P:seed growth; IMP:TAIR.
DR GO; GO:0010089; P:xylem development; IMP:TAIR.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR005540; KNOX1.
DR InterPro; IPR005541; KNOX2.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF03790; KNOX1; 1.
DR Pfam; PF03791; KNOX2; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM01255; KNOX1; 1.
DR SMART; SM01256; KNOX2; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51213; ELK; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..291
FT /note="Homeobox protein knotted-1-like 7"
FT /id="PRO_0000314775"
FT DOMAIN 194..214
FT /note="ELK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT DNA_BIND 215..278
FT /note="Homeobox; TALE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT CONFLICT 1
FT /note="M -> L (in Ref. 4; BAC42940)"
FT /evidence="ECO:0000305"
FT CONFLICT 12
FT /note="T -> S (in Ref. 6; AAM67281)"
FT /evidence="ECO:0000305"
FT CONFLICT 19
FT /note="T -> A (in Ref. 6; AAM67281)"
FT /evidence="ECO:0000305"
FT CONFLICT 185
FT /note="R -> K (in Ref. 6; AAM67281)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 291 AA; 32908 MW; 1F473BEEE07F2B62 CRC64;
MQEAALGMMG ATVGGDGDTA VVAEQNRQLK GEIATHPMYE QLLAAHVACL RVATPIDQLP
IIEAQLSQSH HLLRSYASTA VGYHHDRHEL DNFLAQYVMV LCSFKEQLQQ HVRVHAVEAV
MACREIENNL HSLTGATLGE GSGATMSEDE DDLPMDFSSD NSGVDFSGGH DMTGFGPLLP
TESERSLMER VRQELKLELK QGFKSRIEDV REEIMRKRRA GKLPGDTTTV LKNWWQQHCK
WPYPTEDDKA KLVEETGLQL KQINNWFINQ RKRNWHNNSH SLTSLKSKRK H
