ARAH_SHIFL
ID ARAH_SHIFL Reviewed; 328 AA.
AC P0AE27; P08532; P76304; P76305;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=L-arabinose transport system permease protein AraH;
GN Name=araH; OrderedLocusNames=SF1945, S2038;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for L-
CC arabinose. Probably responsible for the translocation of the substrate
CC across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAN43497.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAP17327.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE005674; AAN43497.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE014073; AAP17327.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_707790.1; NC_004337.2.
DR RefSeq; WP_000100205.1; NZ_WPGW01000033.1.
DR AlphaFoldDB; P0AE27; -.
DR STRING; 198214.SF1945; -.
DR EnsemblBacteria; AAN43497; AAN43497; SF1945.
DR EnsemblBacteria; AAP17327; AAP17327; S2038.
DR GeneID; 1025166; -.
DR GeneID; 58389798; -.
DR KEGG; sfl:SF1945; -.
DR KEGG; sfx:S2038; -.
DR PATRIC; fig|198214.7.peg.2321; -.
DR HOGENOM; CLU_028880_4_1_6; -.
DR OMA; VFTTITN; -.
DR OrthoDB; 1254678at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..328
FT /note="L-arabinose transport system permease protein AraH"
FT /id="PRO_0000059952"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 328 AA; 34211 MW; 72B778D741FB6938 CRC64;
MSSVSTSGSG APKSSFSFGR IWDQYGMLVV FAVLFIACAI FVPNFATFIN MKGLGLAISM
SGMVACGMLF CLASGDFDLS VASVIACAGV TTAVVINLTE SLWIGVAAGL LLGVLCGLVN
GFVIAKLKIN ALITTLATMQ IVRGLAYIIS DGKAVGIEDE SFFALGYANW FGLPAPIWLT
VACLIIFGLL LNKTTFGRNT LAIGGNEEAA RLAGVPVVRT KIIIFVLSGL VSAIAGIILA
SRMTSGQPMT SIGYELIVIS ACVLGGVSLK GGIGKISYVV AGILILGTVE NAMNLLNISP
FAQYVVRGLI LLAAVIFDRY KQKAKRTV
