ID   KNOP1_BOVIN             Reviewed;         452 AA.
AC   A5D7J3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Lysine-rich nucleolar protein 1;
DE   AltName: Full=Testis-specific gene 118 protein;
GN   Name=KNOP1; Synonyms=TSG118;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal muscle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with ZNF106. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI40579.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC140578; AAI40579.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001160078.1; NM_001166606.2.
DR   AlphaFoldDB; A5D7J3; -.
DR   SMR; A5D7J3; -.
DR   STRING; 9913.ENSBTAP00000037276; -.
DR   PaxDb; A5D7J3; -.
DR   PRIDE; A5D7J3; -.
DR   GeneID; 511442; -.
DR   KEGG; bta:511442; -.
DR   CTD; 400506; -.
DR   eggNOG; ENOG502S1WB; Eukaryota.
DR   HOGENOM; CLU_048750_0_0_1; -.
DR   InParanoid; A5D7J3; -.
DR   OrthoDB; 1055972at2759; -.
DR   TreeFam; TF336149; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028124; SMAP_dom.
DR   Pfam; PF15477; SMAP; 1.
PE   2: Evidence at transcript level;
KW   Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Reference proteome;
KW   Ubl conjugation.
FT   CHAIN           1..452
FT                   /note="Lysine-rich nucleolar protein 1"
FT                   /id="PRO_0000321937"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          55..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          300..452
FT                   /note="Interaction with ZNF106"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        76..97
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..127
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..280
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         112
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   MOD_RES         128
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   MOD_RES         258
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   MOD_RES         304
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   MOD_RES         424
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        7
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        126
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        280
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        313
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        347
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        367
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        369
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        401
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
FT   CROSSLNK        436
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q1ED39"
SQ   SEQUENCE   452 AA;  51046 MW;  2FA1676901CC5DA1 CRC64;
     MITKAHKGEV GLGLPEKKKK KKKVVKEPKT QYSVLNSDNY FAEVCPRATP PLKGVIQEQA
     PRMPLVKKKK KKKGHSTICE EHLEPEITLR AGRTERSHSP RTQALGLSKS LSAEKRKSMS
     PGSRVKTSPD PRQDEEVTRV GKKLKKHKKE KKAKEATAFS GRDPWFCEAG NTVYTHSVGK
     DGVREQAALG QKQKQGSPRE HSVKMKKKKK IHWEGDPPLG HPECSWSLES SPTKGSKKKP
     VRVEAPEYIP IGDGSRASVK KKVKSKKRVE QADTEEPALK RKKKKKKRQQ SEVAEEPWEE
     EPDTDLEVVL EKKGNMDEAH IDQVRRKALQ EEIDRESGKT EAYDTKKWTG TQFGQWDTAG
     FENEEQKLKF LKLMGGFKNL PPSFSRPSPT VARPSMALSK KAADTLQRNL QQDYDRALSW
     KYSRGAGLGF STAPAKVFYI DRNASKSIKF ED