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KNOS2_ORYSJ
ID   KNOS2_ORYSJ             Reviewed;         313 AA.
AC   Q0E3C3; B7FAA7; Q94LW5; Q9SXM9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Homeobox protein knotted-1-like 2;
DE   AltName: Full=Homeobox protein HOS58;
GN   Name=HOS58; OrderedLocusNames=Os02g0182800, LOC_Os02g08544;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [MRNA] OF
RP   102-313 (ISOFORM 1), AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12034492; DOI=10.1016/s0378-1119(02)00460-2;
RA   Ito Y., Hirochika H., Kurata N.;
RT   "Organ-specific alternative transcripts of KNOX family class 2 homeobox
RT   genes of rice.";
RL   Gene 288:41-47(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Nipponbare;
RG   The rice full-length cDNA consortium;
RT   "Oryza sativa full length cDNA.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18430022; DOI=10.1111/j.1742-4658.2008.06424.x;
RA   Jain M., Tyagi A.K., Khurana J.P.;
RT   "Genome-wide identification, classification, evolutionary expansion and
RT   expression analyses of homeobox genes in rice.";
RL   FEBS J. 275:2845-2861(2008).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108,
CC       ECO:0000255|PROSITE-ProRule:PRU00559}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q0E3C3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q0E3C3-2; Sequence=VSP_036176;
CC       Name=3;
CC         IsoId=Q0E3C3-3; Sequence=VSP_036177;
CC   -!- TISSUE SPECIFICITY: Isoform 1 is expressed in roots, leaf blades, leaf
CC       sheaths and flowers. Isoform 2 is expressed in leaf blades, leaf
CC       sheaths and flowers. {ECO:0000269|PubMed:12034492}.
CC   -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00559}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF08015.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB061817; BAB55658.1; -; mRNA.
DR   EMBL; AB007627; BAA77821.2; -; mRNA.
DR   EMBL; AP008208; BAF08015.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014958; BAS77320.1; -; Genomic_DNA.
DR   EMBL; AK243352; BAH01555.1; -; mRNA.
DR   RefSeq; XP_015626237.1; XM_015770751.1. [Q0E3C3-1]
DR   RefSeq; XP_015626238.1; XM_015770752.1. [Q0E3C3-3]
DR   AlphaFoldDB; Q0E3C3; -.
DR   SMR; Q0E3C3; -.
DR   STRING; 4530.OS02T0182800-01; -.
DR   PaxDb; Q0E3C3; -.
DR   PRIDE; Q0E3C3; -.
DR   EnsemblPlants; Os02t0182800-01; Os02t0182800-01; Os02g0182800. [Q0E3C3-1]
DR   GeneID; 4328520; -.
DR   Gramene; Os02t0182800-01; Os02t0182800-01; Os02g0182800. [Q0E3C3-1]
DR   KEGG; osa:4328520; -.
DR   eggNOG; KOG0773; Eukaryota.
DR   HOGENOM; CLU_040111_1_0_1; -.
DR   InParanoid; Q0E3C3; -.
DR   OMA; GGAEQSW; -.
DR   OrthoDB; 1070344at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q0E3C3; OS.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR005539; ELK_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR005540; KNOX1.
DR   InterPro; IPR005541; KNOX2.
DR   Pfam; PF03789; ELK; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF03790; KNOX1; 1.
DR   Pfam; PF03791; KNOX2; 1.
DR   SMART; SM01188; ELK; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM01255; KNOX1; 1.
DR   SMART; SM01256; KNOX2; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51213; ELK; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Homeobox protein knotted-1-like 2"
FT                   /id="PRO_0000360005"
FT   DOMAIN          205..225
FT                   /note="ELK"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT   DNA_BIND        226..289
FT                   /note="Homeobox; TALE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          13..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          282..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..130
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12034492"
FT                   /id="VSP_036176"
FT   VAR_SEQ         302..313
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_036177"
SQ   SEQUENCE   313 AA;  33876 MW;  7A857C58196CA75D CRC64;
     MAFHYPDHGL AMDPSSAAAS SPNPSFSPGG GGGGGVGGGE REKAAVAAHP LYERLLEAHV
     ACLRVATPVD QLPRIDAQIA ARPPPLAAAS AAAAAGGPSG GEELDLFMTH YVLLLCSFKE
     QLQQHVRVHA MEAVMGCWEL EQSLQSLTGA SPGEGTGATM SDDEDNQVDS EANMFDGNDG
     SDGMGFGPLM LTEGERSLVE RVRHELKNEL KQGYKEKLVD IREEILRKRR AGKLPGDTAS
     ILKAWWQAHS KWPYPTEDDK ARLVQETGLQ LKQINNWFIN QRKRNWHSNP ASSGEKTKKK
     RNVTGDGGAE QSW
 
 
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